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NCT03429712 · ClinicalTrials.gov registry record · NA
Patient- and Task-specific Radiation Dose Optimization for Pediatric Abdominopelvic CT Applications
A NA study, sponsored by Duke University.
- Terminated
- Registry status
- NA
- Development phase
- 19
- Enrollment target
NCT03429712: Clinical Trial NA study, sponsored by Duke University.
NCT03429712 is a NA study that was terminated before completion, run by Duke University. The registered enrollment target is 19 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03429712, a NA study, was terminated before completion, sponsored by Duke University.
- TERMINATED
- Registry status
- NA
- Development phase
- 19 participants
- Enrollment target
Study Summary
Radiation dose reduction has been a primary driver of technology development in multi-detector computed tomography (MDCT). The optimization of radiation dose for patient and task specific computed tomography (CT) applications continues to be an ongoing challenge, especially in pediatric patients where the desire to reduce radiation dose to lowest possible levels leads to both positive and negative effects. A novel research tool on the Siemens dual source (Flash® and Force ®) CT scanners allows one to assess multiple tube current levels from a single CT acquisition without incurring additional dose to the patient. Tube current is a primary contributor to radiation dose and image noise, which are inversely related. This is achieved by independently adjusting the current of each tube, while maintaining same kV in each x-ray tube. Moreover, Duke's medical physics team has developed a method based on mathematical expressions that allows the creation of incremental dose levels from the acquired image data sets. This innovative and powerful tool can be used to compare diagnostic accuracy, detectability, and many more relevant clinical features amongst multiple tube current levels with the attainment of a single CT acquisition.
Interventions
- DEVICE Dual-source multi-detector computed tomography (DSSE)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 19 participants |
| Start Date | 2018-09-15 |
| Est. Completion | 2019-04-12 |
| Phase | NA |
Why NCT03429712 stopped before completion
NCT03429712 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 19 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).
The record links to 0 conditions, and to 1 intervention - of which Dual-source multi-detector computed tomography (DSSE) is the first listed.
NCT03429712 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03429712 about?
NCT03429712 is a clinical study titled "Patient- and Task-specific Radiation Dose Optimization for Pediatric Abdominopelvic CT Applications". Radiation dose reduction has been a primary driver of technology development in multi-detector computed tomography (MDCT). The optimization of radiation dose for patient and task specific computed tomography (CT) applications continues to be an ongoing challenge, especially in pediatric patients whe...
What is the current status of trial NCT03429712?
This trial is currently terminated. It is a NA study. The enrollment target is 19 participants. The study started on 2018-09-15. Estimated completion is 2019-04-12.
What interventions are being tested in trial NCT03429712?
The interventions under investigation include: Dual-source multi-detector computed tomography (DSSE) (DEVICE).
Who is sponsoring clinical trial NCT03429712?
This trial is sponsored by Duke University, which has 1,725 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03429712's enrollment target sits among peer trials
19 1861st of 2000 higher than 138 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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