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NCT07582211 · ClinicalTrials.gov registry record · NA
Bilevel Positive Airway Pressure (BPAP) for Severe Asthma
A NA study, sponsored by Columbia University.
- Not yet
- Registry status
- NA
- Development phase
- 36
- Enrollment target
NCT07582211: Clinical Trial NA study, sponsored by Columbia University.
NCT07582211 is a NA study that has not yet begun recruiting, run by Columbia University. The registered enrollment target is 36 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07582211, a NA study, has not yet begun recruiting, sponsored by Columbia University.
- NOT YET RECRUITING
- Registry status
- NA
- Development phase
- 36 participants
- Enrollment target
Study Summary
The goal of this clinical trial is to assess the feasibility of early initiation of bilevel positive airway pressure (BPAP) in the emergency department (ED) for children with severe asthma exacerbations. It will also collect preliminary data on the safety and potential effectiveness of this approach. The main questions it aims to answer are: 1. Can eligible patients be successfully enrolled and complete study procedures across multiple sites? 2. What safety events occur with early BPAP use in this population? 3. How do clinical outcomes (such as symptom improvement and need for intensive care) compare between early BPAP and standard care? Researchers will compare early initiation of BPAP plus standard asthma therapy to standard asthma therapy alone to determine whether early BPAP is a feasible and potentially beneficial treatment strategy. Participants will 1) receive standard asthma therapy with or without early BPAP in the ED, 2) be monitored closely during the ED visit and hospitalization, and 3) have clinical data collected from routine care, including asthma severity scores, treatments, and outcomes. The study will enroll approximately 36 participants (about 12 per site) across three sites over one year to inform a future multicenter randomized controlled trial.
Primary Outcome
Proportion of approached, eligible patients who provide consent.
Interventions
- DEVICE Bilevel positive airway pressure ventilation
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 36 participants |
| Start Date | 2026-06 |
| Est. Completion | 2027-08 |
| Phase | NA |
What is known before NCT07582211 opens enrollment
NCT07582211 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 36 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower).
The record links to 0 conditions, and to 1 intervention - of which Bilevel positive airway pressure ventilation is the first listed.
NCT07582211 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07582211 about?
NCT07582211 is a clinical study titled "Bilevel Positive Airway Pressure (BPAP) for Severe Asthma". The goal of this clinical trial is to assess the feasibility of early initiation of bilevel positive airway pressure (BPAP) in the emergency department (ED) for children with severe asthma exacerbations. It will also collect preliminary data on the safety and potential effectiveness of this approach...
What is the current status of trial NCT07582211?
This trial is currently not yet recruiting. It is a NA study. The enrollment target is 36 participants. The study started on 2026-06. Estimated completion is 2027-08.
What interventions are being tested in trial NCT07582211?
The interventions under investigation include: Bilevel positive airway pressure ventilation (DEVICE).
Who is sponsoring clinical trial NCT07582211?
This trial is sponsored by Columbia University, which has 958 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT07582211's enrollment target sits among peer trials
36 1541st of 2000 higher than 437 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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