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NCT04443517 · ClinicalTrials.gov registry record · NA
EEG-Guided Analgesic Titration During General Anesthesia to Improve Early Neurocognitive Recovery in Older Patients
A NA study, sponsored by Columbia University.
- Not yet
- Registry status
- NA
- Development phase
- 600
- Enrollment target
NCT04443517: Clinical Trial NA study, sponsored by Columbia University.
NCT04443517 is a NA study that has not yet begun recruiting, run by Columbia University. The registered enrollment target is 600 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (57% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04443517, a NA study, has not yet begun recruiting, sponsored by Columbia University.
- NOT YET RECRUITING
- Registry status
- NA
- Development phase
- 600 participants
- Enrollment target
Study Summary
The investigators intend to recruit 600 participants to see if alpha power during anesthesia is influenced by analgesic medication and associated with a reduction of delirium following surgery.
Primary Outcome
The EEG data collected during the study duration will be processed using a customized script. Frontal alpha power (i.e., the cumulative power in the EEG alpha range) will be extracted from the EEGs and analyzed to compare the groups for the differences in the frontal alpha power.
Interventions
- PROCEDURE Alpha Optimization
- BEHAVIORAL Emergence from anesthesia with Dexmedetomidine
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 600 participants |
| Start Date | 2026-04-01 |
| Est. Completion | 2031-03-31 |
| Phase | NA |
What is known before NCT04443517 opens enrollment
NCT04443517 is an interventional study that assigns participants to a tested intervention. The registered 600 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (57% lower).
The record links to 0 conditions, and to 2 interventions - of which Alpha Optimization is the first listed.
NCT04443517 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04443517 about?
NCT04443517 is a clinical study titled "EEG-Guided Analgesic Titration During General Anesthesia to Improve Early Neurocognitive Recovery in Older Patients". The investigators intend to recruit 600 participants to see if alpha power during anesthesia is influenced by analgesic medication and associated with a reduction of delirium following surgery.
What is the current status of trial NCT04443517?
This trial is currently not yet recruiting. It is a NA study. The enrollment target is 600 participants. The study started on 2026-04-01. Estimated completion is 2031-03-31.
What interventions are being tested in trial NCT04443517?
The interventions under investigation include: Alpha Optimization (PROCEDURE), Emergence from anesthesia with Dexmedetomidine (BEHAVIORAL).
Who is sponsoring clinical trial NCT04443517?
This trial is sponsored by Columbia University, which has 958 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04443517's enrollment target sits among peer trials
600 162nd of 2000 higher than 1,827 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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