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NCT07567495 · ClinicalTrials.gov registry record · Phase 4
Adding Dexmedetomidine or Clonidine to Spinal Anesthesia for Cesarean Delivery
A Phase 4 study, sponsored by Columbia University.
- Not yet
- Registry status
- Phase 4
- Development phase
- 150
- Enrollment target
NCT07567495: Clinical Trial Phase 4 study, sponsored by Columbia University.
NCT07567495 is a Phase 4 study that has not yet begun recruiting, run by Columbia University. The registered enrollment target is 150 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (71% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07567495, a Phase 4 study, has not yet begun recruiting, sponsored by Columbia University.
- NOT YET RECRUITING
- Registry status
- Phase 4
- Development phase
- 150 participants
- Enrollment target
Study Summary
This study will examine whether addition of dexmedetomidine or clonidine (two alpha-2 adrenergic agonists) will improve the comfort of patients during spinal anesthesia for cesarean delivery. When added to standard spinal anesthesia consisting of bupivacaine (a local anesthetic) and fentanyl and morphine (two opioids), these medications may decrease some of the pulling/tugging/pressure sensations that patients sometimes feel during cesarean delivery, may prolong the anesthetic time, and may decrease postoperative pain.
Primary Outcome
The primary outcome of this study is the incidence of self-reported intraoperative discomfort, defined as pain or uncomfortable pressure, tugging, pulling feeling during cesarean delivery. At specific timepoints during cesarean delivery surgery, the patient will be asked "Do you feel uncomfortable sensations (pain, pressure, pulling, tugging)?" If the answer is "yes, " she will be asked "Do you want medication to treat it?" The timepoints specified will be: 1. Foley (urinary) catheter placeme
Interventions
- DRUG Dexmedetomidine
- DRUG Clonidine
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 150 participants |
| Start Date | 2026-06 |
| Est. Completion | 2028-05 |
| Phase | Phase 4 |
What is known before NCT07567495 opens enrollment
NCT07567495 is an interventional study that assigns participants to a tested intervention. The registered 150 participants enrollment target is mid-sized for trials with a published cap, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (71% lower).
The record links to 0 conditions, and to 2 interventions - of which Dexmedetomidine is the first listed.
NCT07567495 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07567495 about?
NCT07567495 is a clinical study titled "Adding Dexmedetomidine or Clonidine to Spinal Anesthesia for Cesarean Delivery". This study will examine whether addition of dexmedetomidine or clonidine (two alpha-2 adrenergic agonists) will improve the comfort of patients during spinal anesthesia for cesarean delivery. When added to standard spinal anesthesia consisting of bupivacaine (a local anesthetic) and fentanyl and mor...
What is the current status of trial NCT07567495?
This trial is currently not yet recruiting. It is a Phase 4 study. The enrollment target is 150 participants. The study started on 2026-06. Estimated completion is 2028-05.
What interventions are being tested in trial NCT07567495?
The interventions under investigation include: Dexmedetomidine (DRUG), Clonidine (DRUG).
Who is sponsoring clinical trial NCT07567495?
This trial is sponsored by Columbia University, which has 958 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT07567495's enrollment target sits among peer trials
150 533rd of 2000 higher than 1,436 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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