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NCT07060261 · ClinicalTrials.gov registry record · NA

Pre-Op MRI on Margin Status for Transoral Robotic Surgery for HPV+ Tonsillar Squamous Cell Carcinoma

A NA study, sponsored by Case Comprehensive Cancer Center.

Recruiting
Registry status
NA
Development phase
30
Enrollment target

NCT07060261: Recruiting NA study, sponsored by Case Comprehensive Cancer Center.

NCT07060261 is a NA study that is actively recruiting participants, run by Case Comprehensive Cancer Center. The registered enrollment target is 30 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT07060261, a NA study, is actively recruiting participants, sponsored by Case Comprehensive Cancer Center.

RECRUITING
Registry status
NA
Development phase
30 participants
Enrollment target

Study Summary

This prospective research study aims to see if pre-operative MRI can predict the margin status after transoral robotic surgery (TORS) for human papillomavirus positive (HPV+) tonsillar squamous cell carcinoma (SCC). The pre-operative MRI will have a standard MR neck without and with contrast, with added axial T2 weighted sequence and T2 SPACE sequence through the tonsils. Three neuroradiologists will grade the thickness of the pharyngeal constrictor muscle (the muscle that surrounds the tonsils) on a five-point scale. The study will determine if the pre-operative MRI grading will correlate with positive, insecure (\<1mm), or secure (\>1mm) margin during TORS surgery for your HPV+ tonsillar SCC.

Primary Outcome

Accuracy will be summarized using the area under the receiver operating characteristics curve (AUC)

Interventions

  • PROCEDURE Transoral robotic surgery+MRI

Trial Details

FieldValue
Enrollment Target 30 participants
Start Date 2025-11-26
Est. Completion 2026-09
Phase NA
Case Comprehensive Cancer Center

407 total trials

What NCT07060261 shows while recruiting

NCT07060261 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower).

The record links to 0 conditions, and to 1 intervention - of which Transoral robotic surgery+MRI is the first listed.

NCT07060261 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT07060261 about?

NCT07060261 is a clinical study titled "Pre-Op MRI on Margin Status for Transoral Robotic Surgery for HPV+ Tonsillar Squamous Cell Carcinoma". This prospective research study aims to see if pre-operative MRI can predict the margin status after transoral robotic surgery (TORS) for human papillomavirus positive (HPV+) tonsillar squamous cell carcinoma (SCC). The pre-operative MRI will have a standard MR neck without and with contrast, with a...

What is the current status of trial NCT07060261?

This trial is currently recruiting. It is a NA study. The enrollment target is 30 participants. The study started on 2025-11-26. Estimated completion is 2026-09.

What interventions are being tested in trial NCT07060261?

The interventions under investigation include: Transoral robotic surgery+MRI (PROCEDURE).

Who is sponsoring clinical trial NCT07060261?

This trial is sponsored by Case Comprehensive Cancer Center, which has 407 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT07060261's enrollment target sits among peer trials

30 1593rd of 2000 higher than 299 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT07060261, the US trial registry maintained by the National Library of Medicine. NCT07060261 (small enrollment · none site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.