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NCT07241585 · ClinicalTrials.gov registry record · NA
Vitamin D Effects on Immune Microenvironment of Nonmelanoma Skin Cancer After Photodynamic Therapy (PDT)
A NA study, sponsored by Case Comprehensive Cancer Center.
- Recruiting
- Registry status
- NA
- Development phase
- 54
- Enrollment target
NCT07241585 is a NA study that is actively recruiting participants, run by Case Comprehensive Cancer Center. The registered enrollment target is 54 participants.
The verdict
NCT07241585, a NA study, is actively recruiting participants, sponsored by Case Comprehensive Cancer Center.
- RECRUITING
- Registry status
- NA
- Development phase
- 54 participants
- Enrollment target
Study Summary
This research study is for people who have been diagnosed with a nonmelanoma skin cancer (either basal cell carcinoma or squamous cell carcinoma) and are planning to receive either Mohs surgery or ED\&C (electrodessication \& curettage) as part of clinical care. The purpose of this study is to understand how photodynamic therapy (PDT) with or without Vitamin D can promote an immune response to skin cancer. For this study, participants will be randomized (randomly assigned) and asked to take Vitamin D or placebo for 6 days and come to the clinic for a single PDT treatment 1-14 days prior to their surgery. At this visit, photographs of participant's skin cancer will be taken, and participants will undergo PDT treatment. The study team will also take photos on the day of Mohs surgery or ED\&C. There will be up to two blood draws for research. If participants do not want to come in for a PDT treatment prior to their Mohs surgery or ED\&C, they will have the option to participate by only allowing the study team to collect data about their skin cancer and their tissue from Mohs surgery or ED\&C.
Interventions
- OTHER Placebo
- DIETARY_SUPPLEMENT Vitamin D (VitD)
- OTHER Photodynamic therapy (PDT)
- PROCEDURE Mohs surgery or electrodessication & curettage (ED&C) (standard of care)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 54 participants |
| Start Date | 2026-02-25 |
| Est. Completion | 2027-08 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07241585
The ClinicalTrials.gov registry entry for NCT07241585 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 54 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Case Comprehensive Cancer Center, which has 407 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 4 interventions - of which Placebo is the first listed.
NCT07241585 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT07241585 about?
NCT07241585 is a clinical study titled "Vitamin D Effects on Immune Microenvironment of Nonmelanoma Skin Cancer After Photodynamic Therapy (PDT)". This research study is for people who have been diagnosed with a nonmelanoma skin cancer (either basal cell carcinoma or squamous cell carcinoma) and are planning to receive either Mohs surgery or ED\&C (electrodessication \& curettage) as part of clinical care. The purpose of this study is to under...
What is the current status of trial NCT07241585?
This trial is currently recruiting. It is a NA study. The enrollment target is 54 participants. The study started on 2026-02-25. Estimated completion is 2027-08.
What interventions are being tested in trial NCT07241585?
The interventions under investigation include: Placebo (OTHER), Vitamin D (VitD) (DIETARY_SUPPLEMENT), Photodynamic therapy (PDT) (OTHER), Mohs surgery or electrodessication & curettage (ED&C) (standard of care) (PROCEDURE).
Who is sponsoring clinical trial NCT07241585?
This trial is sponsored by Case Comprehensive Cancer Center, which has 407 total clinical trials registered on ClinicalTrials.gov.
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