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NCT05565118 · ClinicalTrials.gov registry record · Phase 1
Prospective Surgical Study on the Pattern of Electrical Activity in High Grade Glioma as a Predictor of Progression
A Phase 1 study of Glioblastoma and High Grade Glioma, sponsored by Case Comprehensive Cancer Center.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 10
- Enrollment target
- 1
- Study location
NCT05565118: Recruiting Phase 1 study of Glioblastoma and High Grade Glioma, sponsored by Case Comprehensive Cancer Center.
NCT05565118 is a Phase 1 study of Glioblastoma and High Grade Glioma that is actively recruiting participants, run by Case Comprehensive Cancer Center. The registered enrollment target is 10 participants, below the 109-participant average among 199 other Glioblastoma trials with a reported enrollment target (91% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05565118, a Phase 1 study of Glioblastoma and High Grade Glioma, is actively recruiting participants, sponsored by Case Comprehensive Cancer Center.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 10 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to test the safety and feasibility of recording brain activity within and around high-grade glioma tumors at the time of surgery. A small biopsy will be taken at the sites of the recordings.
Primary Outcome
To describe the pattern of electrical activity (neuronal hyperexcitability) in brain surrounding the enhancing tumor during open surgery in patients with high grade gliomas and its correlation with progression
Conditions Studied
Interventions
- PROCEDURE Standard Surgical Treatment
- PROCEDURE Intraoperative Electrocorticography
Study Locations (1)
Ohio
- Cleveland Clinic Taussig Cancer Institute, Case Comprehensive Cancer Center - Cleveland
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 10 participants |
| Start Date | 2024-04-09 |
| Est. Completion | 2026-12 |
| Phase | Phase 1 |
What NCT05565118 shows while recruiting
NCT05565118 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 10 participants, a relatively small participant target, below the 109-participant average among 199 other Glioblastoma trials with a reported enrollment target (91% lower).
The record links to 2 conditions, with Glioblastoma appearing as the primary indexed condition, and to 2 interventions - of which Standard Surgical Treatment is the first listed.
NCT05565118 reports a single indexed study location in Ohio.
Frequently Asked Questions
What is clinical trial NCT05565118 about?
NCT05565118 is a clinical study titled "Prospective Surgical Study on the Pattern of Electrical Activity in High Grade Glioma as a Predictor of Progression". The purpose of this study is to test the safety and feasibility of recording brain activity within and around high-grade glioma tumors at the time of surgery. A small biopsy will be taken at the sites of the recordings.
What is the current status of trial NCT05565118?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 10 participants. The study started on 2024-04-09. Estimated completion is 2026-12.
What conditions does trial NCT05565118 study?
This clinical trial studies the following conditions: Glioblastoma, High Grade Glioma.
What interventions are being tested in trial NCT05565118?
The interventions under investigation include: Standard Surgical Treatment (PROCEDURE), Intraoperative Electrocorticography (PROCEDURE).
Who is sponsoring clinical trial NCT05565118?
This trial is sponsored by Case Comprehensive Cancer Center, which has 407 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05565118 being conducted?
This trial has 1 study location across Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Glioblastoma
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05565118's enrollment target sits among peer trials
10 189th of 199 higher than 6 of 199 other Glioblastoma trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Glioblastoma trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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