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NCT05579509 · ClinicalTrials.gov registry record · Early Phase 1
Personalizing Preprocedural Sedation for Regional Anesthesia
A Early Phase 1 study, sponsored by Brigham and Women's Hospital.
- Completed
- Registry status
- Early Phase 1
- Development phase
- 82
- Enrollment target
NCT05579509: Completed Early Phase 1 study, sponsored by Brigham and Women's Hospital.
NCT05579509 is a Early Phase 1 study that has completed, run by Brigham and Women's Hospital. The registered enrollment target is 82 participants, above the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (55% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05579509, a Early Phase 1 study, has completed, sponsored by Brigham and Women's Hospital.
- COMPLETED
- Registry status
- Early Phase 1
- Development phase
- 82 participants
- Enrollment target
Study Summary
This is a prospective, randomized study in patients who receive a nerve block prior to surgery. The aim is to investigate whether individual differences in psychosocial and pain profiles may play a role in how patients experience sedation for regional anesthesia. The study will utilize a mixed-methods approach, including a randomized controlled intervention and semi-structured interviews, in order to systematically investigate the relationship between an individual patient's level of catastrophizing and efficacy of procedural sedation, while exploring patient satisfaction with the preoperative nerve block experience.
Primary Outcome
Procedural pain rating during the nerve block procedure on a 0 (no pain) to 10 (severe pain) Likert scale. Higher scores represent a worse outcome.
Interventions
- DRUG Midazolam and Fentanyl
- BEHAVIORAL Educational Reassurance
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 82 participants |
| Start Date | 2022-10-22 |
| Est. Completion | 2024-05-24 |
| Phase | Early Phase 1 |
What the finished NCT05579509 record still lists
NCT05579509 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 82 participants, a relatively small participant target, above the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (55% higher).
The record links to 0 conditions, and to 2 interventions - of which Midazolam and Fentanyl is the first listed.
NCT05579509 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05579509 about?
NCT05579509 is a clinical study titled "Personalizing Preprocedural Sedation for Regional Anesthesia". This is a prospective, randomized study in patients who receive a nerve block prior to surgery. The aim is to investigate whether individual differences in psychosocial and pain profiles may play a role in how patients experience sedation for regional anesthesia. The study will utilize a mixed-metho...
What is the current status of trial NCT05579509?
This trial is currently completed. It is a Early Phase 1 study. The enrollment target is 82 participants. The study started on 2022-10-22. Estimated completion is 2024-05-24.
What interventions are being tested in trial NCT05579509?
The interventions under investigation include: Midazolam and Fentanyl (DRUG), Educational Reassurance (BEHAVIORAL).
Who is sponsoring clinical trial NCT05579509?
This trial is sponsored by Brigham and Women's Hospital, which has 937 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05579509's enrollment target sits among peer trials
82 266th of 2000 higher than 1,733 of 2,000 other Early Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Early Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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