Brigham and Women's Hospital

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Brigham and Women's Hospital sits in the top decile of US sponsors by registered trial count (#35 of 15,742 sponsors by registered trial count).

937 total trials 145 currently recruiting 608 completed early-phase tilt top decile by trial count

Brigham and Women's Hospital: 937 sponsored US clinical trials, 145 recruiting.

Brigham and Women's Hospital sponsors 937 registered US clinical trials on ClinicalTrials.gov, 145 of them currently recruiting, and 608 completed. 124 of these trials are in Phase 3-4 (later-stage) and 197 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Type 2 Diabetes, with 13 trials.

Top-decile sponsor footprint

Brigham and Women's Hospital ranks in the top decile of sponsors by registered trial count (#35 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

D 64/100

608 of 677 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (89.8%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

937 total, page 19 of 19

COMPLETED NA

The Effects of Modafinil to Counteract the Adverse Metabolic Consequences of Sleep Restriction

NCT00895570

COMPLETED Phase 3

Rho Kinase in Patients With Atherosclerosis

NCT00115830

COMPLETED Phase 4

Testosterone Replacement in Older Men and Atherosclerosis Progression

NCT00287586

TERMINATED Phase 4

Erythropoietin in Radiocontrast Induced Nephropathy (ERIN) Trial

NCT00476619

COMPLETED NA

Hypoglycemia and Autonomic Nervous System Function

NCT01816893

COMPLETED Phase 3

Acupuncture Analgesia in Relation to Psychiatric Comorbidity

NCT00307788

COMPLETED

Ventricular-Vascular Coupling in Heart Failure

NCT00207220

COMPLETED Phase 2

ARREST PAD (Peripheral Arterial Disease)

NCT00153166

COMPLETED Phase 1

Patient- and Physician-Based Osteoporosis Education

NCT00073190

COMPLETED NA

Preventing Obesity Using Novel Dietary Strategies

NCT00072995

COMPLETED NA

Aldosterone and Vascular Disease in Diabetes Mellitus

NCT00214825

COMPLETED Phase 4

Comparison of Crinone 8% Intravaginal Gel and IM Progesterone Supplementation for In Vitro Fertilization (IVF)

NCT00656201

COMPLETED

Impact of Sleep Disruption on the Menstrual Cycle

NCT00456222

COMPLETED NA

The Impact of Pharmacist Recommendations on Quality of Care in Diabetic Patients

NCT00122421

COMPLETED Phase 2

Clinical Neuropharmacology of Pain in Spinal Cord Injury- Dextromethorphan/Lidocaine Combination Clinical Trial

NCT02218203

COMPLETED Phase 2

Nesiritide Infusion for the Treatment of Decompensated Heart Failure and Renal Dysfunction

NCT00119691

COMPLETED Phase 3

Predicting the Response to Montelukast by Genetic Variation in Asthmatics

NCT00116324

COMPLETED Phase 2

Clinical Neuropharmacology of Pain in Spinal Cord Injury- Dextromethorphan Dose Response Clinical Trial

NCT01435798

COMPLETED Phase 2

Prevention of Atherosclerosis and Heart Disease in Patients With Systemic Lupus Erythematosis (SLE)

NCT00054938

COMPLETED Phase 1

A Randomized, Double-Blind, Placebo-Controlled Trial of Simvastatin on Subarachnoid Hemorrhage-Induced Vasospasm

NCT00235963

COMPLETED Phase 2

Impact of Literacy Level on Patient Education and Health Among People With Arthritis

NCT00023205

COMPLETED Phase 2

The Effect of Fasudil on Vascular Function in Humans

NCT00120718

COMPLETED Phase 2

The Role of Mineralocorticoid Receptors in Vascular Function

NCT00759525

COMPLETED NA

Neurosurgical Use of Interstitial Laser Therapy (ILT)

NCT00207350

COMPLETED Phase 4

Relaxation Response Training for the Treatment of Rheumatoid Arthritis

NCT00056667

COMPLETED Phase 2

Study to Evaluate the Efficacy of Dronabinol (Marinol) as Add-On Therapy for Patients on Opioids for Chronic Pain

NCT00153192

COMPLETED NA

Imaging of Plaque With Magnetic Resonance Imaging (MRI)

NCT00115856

COMPLETED Phase 4

Soy Isoflavone Tablets: Effects on Sleep, Quality of Life, Symptoms and Cognitive Function in Menopausal Women

NCT01401946

TERMINATED

Vascular Dysfunction in Diabetes: Genes and Hormones

NCT01511042

TERMINATED

Genetic Mechanisms in Human Hypertension

NCT01456208

COMPLETED Phase 2

Signaling Mechanisms and Vascular Function in Patients With Diabetes Mellitus

NCT00762671

COMPLETED Phase 2

The Role of Endothelin in Pulmonary Hypertension

NCT00759408

COMPLETED NA

The Contribution of Endothelin to Vasomotor Function in Diseased Coronary Arteries

NCT00115583

COMPLETED Phase 3

Lyme Disease Prevention Program

NCT00000432

COMPLETED Phase 2

Psychoeducational Approach to Improve Health in Lupus

NCT00000417

COMPLETED

Evaluating the Relationship Between Fatty Acids and Heart Disease

NCT00404872

COMPLETED Phase 3

The Effects of a Results Management System on Physician Awareness of Post-Discharge Test Results

NCT00146354

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Phase Distribution

PhaseTrial count
Phase 1 90
Phase 2 107
Phase 3 47
Phase 4 77

What is open in the Brigham and Women's Hospital pipeline

145 recruiting of 937 indexed (15% open); 608 completed (65%).

Phase mix: 124 late (III/IV) vs 197 early (I/II) (early-phase heavy).

Top condition: Type 2 Diabetes (13 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Brigham and Women's Hospital: open-pipeline peers nationwide

Peers matched on 937 registered trials and 15% open enrollment, not the therapeutic-area sidebar.

Brigham and Women's Hospital sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 05001,0001,500 5%10%15%20% Total trials Recruiting share Brigham and Women's HospitalColumbia UniversityHoffmann-La RocheUniversity of MinnesotaUniversity of California, Los AngelesIncyte CorporationNorthwestern UniversityNationwide Children's HospitalUniversity of Michigan Rogel Cancer Center
Brigham and Women's Hospital sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Brigham and Women's Hospital sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 937 trials (± recruiting share)

Sponsors near 15% open enrollment (± trial volume)

What to do with this Brigham and Women's Hospital page

937 registered trials is a research-attention snapshot, not an endorsement of Brigham and Women's Hospital or any single study.

  • 145 of Brigham and Women's Hospital's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Type 2 Diabetes is the condition Brigham and Women's Hospital studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Type 2 Diabetes trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Brigham and Women's Hospital pipeline card: 937 registered trials from official public datasets.Report a data error.