Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT00153166 · ClinicalTrials.gov registry record · Phase 2
ARREST PAD (Peripheral Arterial Disease)
A Phase 2 study, sponsored by Brigham and Women's Hospital.
- Completed
- Registry status
- Phase 2
- Development phase
- 76
- Enrollment target
NCT00153166: Completed Phase 2 study, sponsored by Brigham and Women's Hospital.
NCT00153166 is a Phase 2 study that has completed, run by Brigham and Women's Hospital. The registered enrollment target is 76 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (43% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00153166, a Phase 2 study, has completed, sponsored by Brigham and Women's Hospital.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 76 participants
- Enrollment target
Study Summary
This trial will test the hypothesis that inflammation and insulin resistance contribute to reduced walking distance in subjects with intermittent claudication by impairing vascular reactivity and skeletal muscle metabolic function.
Primary Outcome
Net calf skeletal muscle glucose uptake determined by Patlak modeling.
Interventions
- DRUG atorvastatin and pioglitazone
- DRUG atorvastatin/placebo
- DRUG pioglitazone/placebo
- DRUG placebo/placebo
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 76 participants |
| Start Date | 2004-01 |
| Est. Completion | 2011-12 |
| Phase | Phase 2 |
What the finished NCT00153166 record still lists
NCT00153166 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 76 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (43% lower).
The record links to 0 conditions, and to 4 interventions - of which atorvastatin and pioglitazone is the first listed.
NCT00153166 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00153166 about?
NCT00153166 is a clinical study titled "ARREST PAD (Peripheral Arterial Disease)". This trial will test the hypothesis that inflammation and insulin resistance contribute to reduced walking distance in subjects with intermittent claudication by impairing vascular reactivity and skeletal muscle metabolic function.
What is the current status of trial NCT00153166?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 76 participants. The study started on 2004-01. Estimated completion is 2011-12.
What interventions are being tested in trial NCT00153166?
The interventions under investigation include: atorvastatin and pioglitazone (DRUG), atorvastatin/placebo (DRUG), pioglitazone/placebo (DRUG), placebo/placebo (DRUG).
Who is sponsoring clinical trial NCT00153166?
This trial is sponsored by Brigham and Women's Hospital, which has 937 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00153166's enrollment target sits among peer trials
76 893rd of 2000 higher than 1,101 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT02615184 · 76 participants · Phase 2
A Study to Check the Safety of Dexlansoprazole and Learn If it Can Heal Erosive Esophagitis (EE) and Keep it Healed in Children 2 to 11 Years Old
- NCT02821741 · 76 participants · NA
Effects of External Ear Stimulation on Pain Perception and Mood
- NCT03019757 · 76 participants
Distinguishing Between Alzheimer's Disease, Lewy Body Dementia, and Parkinson's Disease
- NCT03353584 · 76 participants · NA
Effect of Virtual Reality Technology for Pain Management of Vaso-Occlusive Crisis in Patients With Sickle Cell Disease
Similar registry start date
- NCT05988463 · started 2027-01-01 · Phase 1
Dose-Escalation Study of Artesunate Patients With IPF
- NCT07219706 · started 2026-12-10 · NA
Dietary Fiber and Time Restricted Eating
- NCT02831335 · started 2026-12-01
Technical Development of Multi-Parametric Renocerebral MRI
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia