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NCT04125862 · ClinicalTrials.gov registry record · NA
Pain in Fibrous Dysplasia
A NA study, sponsored by Boston Children's Hospital.
- Completed
- Registry status
- NA
- Development phase
- 37
- Enrollment target
NCT04125862: Completed NA study, sponsored by Boston Children's Hospital.
NCT04125862 is a NA study that has completed, run by Boston Children's Hospital. The registered enrollment target is 37 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04125862, a NA study, has completed, sponsored by Boston Children's Hospital.
- COMPLETED
- Registry status
- NA
- Development phase
- 37 participants
- Enrollment target
Study Summary
Pain remains a common and frequently debilitating symptom, particularly during adulthood of Fibrous Dysplasia/McCune-Albright Syndrome (FD/MAS). For many FD/MAS patients, the amount of pain perceived is not commensurate with the level of detectable musculoskeletal pathology. Using a combination of clinical and biological assessments, this investigation aims to understand what drives pain in FD/MAS.
Primary Outcome
• % signal difference within striatal and limbic network structures during evoked-heat pain fMRI between FD/MAS patients with pain, FD/MAS patients without pain and matched, healthy volunteers.
Interventions
- DIAGNOSTIC_TEST MRI-based Neuroimaging
- DIAGNOSTIC_TEST Non-contrast MRI
- DIAGNOSTIC_TEST 18F-FDG-PET/CT
- DIAGNOSTIC_TEST 18F-NaF-PET/CT
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 37 participants |
| Start Date | 2021-01-05 |
| Est. Completion | 2025-12-01 |
| Phase | NA |
What the finished NCT04125862 record still lists
NCT04125862 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 37 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower).
The record links to 0 conditions, and to 4 interventions - of which MRI-based Neuroimaging is the first listed.
NCT04125862 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04125862 about?
NCT04125862 is a clinical study titled "Pain in Fibrous Dysplasia". Pain remains a common and frequently debilitating symptom, particularly during adulthood of Fibrous Dysplasia/McCune-Albright Syndrome (FD/MAS). For many FD/MAS patients, the amount of pain perceived is not commensurate with the level of detectable musculoskeletal pathology. Using a combination of c...
What is the current status of trial NCT04125862?
This trial is currently completed. It is a NA study. The enrollment target is 37 participants. The study started on 2021-01-05. Estimated completion is 2025-12-01.
What interventions are being tested in trial NCT04125862?
The interventions under investigation include: MRI-based Neuroimaging (DIAGNOSTIC_TEST), Non-contrast MRI (DIAGNOSTIC_TEST), 18F-FDG-PET/CT (DIAGNOSTIC_TEST), 18F-NaF-PET/CT (DIAGNOSTIC_TEST).
Who is sponsoring clinical trial NCT04125862?
This trial is sponsored by Boston Children's Hospital, which has 462 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04125862's enrollment target sits among peer trials
37 1540th of 2000 higher than 460 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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