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NCT07374640 · ClinicalTrials.gov registry record · Early Phase 1

Virtual Reality and Biofeedback for Adolescents With Chronic Dizziness

A Early Phase 1 study, sponsored by Boston Children's Hospital.

Not yet
Registry status
Early Phase 1
Development phase
12
Enrollment target

NCT07374640: Clinical Trial Early Phase 1 study, sponsored by Boston Children's Hospital.

NCT07374640 is a Early Phase 1 study that has not yet begun recruiting, run by Boston Children's Hospital. The registered enrollment target is 12 participants, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (77% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT07374640, a Early Phase 1 study, has not yet begun recruiting, sponsored by Boston Children's Hospital.

NOT YET RECRUITING
Registry status
Early Phase 1
Development phase
12 participants
Enrollment target

Study Summary

Both persistent postural-perceptual dizziness (PPPD) and vestibular migraine (VM) are common diagnoses in patients presenting to physicians for evaluation of vestibular symptoms such as dizziness and vertigo. Although they are most often described in the adult population, they are also common in children and adolescents with dizziness. Chronic dizziness profoundly affects quality of life, often keeping children out of school and inhibiting their participation in the normal activities of childhood and adolescence. Overall, chronic dizziness is suspected to be due in large part to a "rewiring" of the brain that alters how cues related to balance and orientation are processed, with overreliance on visual inputs to maintain balance and equilibrium being a common development. Thus, chronic dizziness, especially that which is due to PPPD, is often caused by visual triggers. A multi-modal approach is often taken to treat chronic dizziness, attempting to recalibrate this maladaptive "rewiring" and return the sensory system to normal function. Given the role that visual inputs play in developing and perpetuating chronic dizziness, habituation to visual stimuli should be a significant component to treatment. Treatments often include cognitive behavioral therapy (CBT), systematic desensitization exposure response prevention (SDERP), and biofeedback therapy (BFB). However, these visually provoked symptoms are often resistant to treatment. One reason for this may be that visual stimuli are difficult to replicate in the clinic or office. One way to address this gap in treatment is through virtual reality (VR) technology, which immerses patients in realistic visual environments. VR has not been explicitly described in the treatment of PPPD or chronic dizziness, but it has been piloted, and shown to be effective, in the rehabilitation of peripheral vestibular dysfunction. This study aims to integrate VR into the current PPPD/chronic dizziness techniques of CBT, SDERP, and BFB. Th

Primary Outcome

A 25-item self-assessment that quantifies the impact of dizziness on daily functioning. The DHI measures self-perceived handicap due to dizziness in the functional, emotional, and physical domains. Higher score corresponds to a greater perceived handicap due to dizziness.

Interventions

  • DEVICE Virtual Reality

Trial Details

FieldValue
Enrollment Target 12 participants
Start Date 2026-03
Est. Completion 2027-05
Phase Early Phase 1
Boston Children's Hospital

462 total trials

What is known before NCT07374640 opens enrollment

NCT07374640 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 12 participants, a relatively small participant target, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (77% lower).

The record links to 0 conditions, and to 1 intervention - of which Virtual Reality is the first listed.

NCT07374640 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT07374640 about?

NCT07374640 is a clinical study titled "Virtual Reality and Biofeedback for Adolescents With Chronic Dizziness". Both persistent postural-perceptual dizziness (PPPD) and vestibular migraine (VM) are common diagnoses in patients presenting to physicians for evaluation of vestibular symptoms such as dizziness and vertigo. Although they are most often described in the adult population, they are also common in chi...

What is the current status of trial NCT07374640?

This trial is currently not yet recruiting. It is a Early Phase 1 study. The enrollment target is 12 participants. The study started on 2026-03. Estimated completion is 2027-05.

What interventions are being tested in trial NCT07374640?

The interventions under investigation include: Virtual Reality (DEVICE).

Who is sponsoring clinical trial NCT07374640?

This trial is sponsored by Boston Children's Hospital, which has 462 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT07374640's enrollment target sits among peer trials

12 1529th of 2000 higher than 401 of 2,000 other Early Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Early Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT07374640, the US trial registry maintained by the National Library of Medicine. NCT07374640 (small enrollment · none site footprint · not yet recruiting) retrieved and formatted by PlainTrial, see methodology.