Biogen

334 total trials 21 currently recruiting 237 completed

Biogen sponsors 334 registered US clinical trials on ClinicalTrials.gov, 21 of them currently recruiting, and 237 completed. 84 of these trials are in Phase 3-4 (later-stage) and 198 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Multiple Sclerosis, with 13 trials.

Trial Pipeline

334 total, page 6 of 7

COMPLETED Phase 1

BIIB033 Single Ascending Dose Study in Healthy Volunteer Subjects

NCT01052506

COMPLETED Phase 1

BIIB014 Cardiovascular Monitoring Study

NCT01035515

COMPLETED Phase 2

Hormone Receptor Positive Metastatic Breast Cancer (HR+ mBC) BIIB021 Plus Aromasin Schedule Finding

NCT01004081

COMPLETED Phase 1

Effect of Food and Antacid on BIIB021 With Advanced Solid Tumors

NCT01017198

COMPLETED Phase 1

A Study of BIIB022 in Combination With Paclitaxel and Carboplatin in Subjects With Non-Small Cell Lung Cancer

NCT00970580

COMPLETED Phase 1

Sorafenib With BIIB022 in Hepatocellular Carcinoma (HCC)

NCT00956436

COMPLETED Phase 1

Study to Investigate the Effect of GSK1014802 on Ambulatory Blood Pressure

NCT00955396

COMPLETED Phase 3

Efficacy and Safety Study of Peginterferon Beta-1a in Participants With Relapsing Multiple Sclerosis

NCT00906399

COMPLETED Phase 2

Trial to Determine the Effects of Bardoxolone Methyl on eGFR in Patients With Type 2 Diabetes and Chronic Kidney Disease

NCT00811889

COMPLETED Phase 1

BG9928 in Subjects With Hepatic Impairment

NCT00858156

COMPLETED Phase 3

BG00012 Monotherapy Safety and Efficacy Extension Study in Multiple Sclerosis (MS)

NCT00835770

TERMINATED Phase 2

Oral Tonapofylline (BG9928) in Patients With Heart Failure and Renal Insufficiency

NCT00745316

COMPLETED Phase 3

Evaluate the Safe and Effective Use of the Avonex® Single-Use Autoinjector in Multiple Sclerosis Subjects

NCT00828204

TERMINATED Phase 1

Study to Explore the Effect of Mefloquine in Participants With Progressive Multifocal Leukoencephalopathy (PML)

NCT00746941

COMPLETED Phase 4

A Pharmacokinetic (PK) Study of Natalizumab (Tysabri) at Steady State

NCT00744679

COMPLETED Phase 1

BIIB023 (Anti-TWEAK) in Subjects With Rheumatoid Arthritis

NCT00771329

TERMINATED Phase 3

Immunogenicity and Safety of Subcutaneously-administered Avonex (Interferon Beta-1a) in Multiple Sclerosis (MS) Patients

NCT00784836

TERMINATED Phase 1

Study of Natalizumab in Relapsed/Refractory Multiple Myeloma

NCT00675428

TERMINATED Phase 1

Mechanism of Action of Galiximab in Subjects With Previously Untreated Follicular Non-Hodgkin's Lymphoma

NCT00651443

COMPLETED Phase 3

Study to Assess the Safety and Tolerability of IV Tonapofylline in Subjects With Acute Decompensated Heart Failure (ADHF) and Renal Insufficiency

NCT00709865

TERMINATED

CD INFORM: Investigating Natalizumab Through Further Observational Research and Monitoring

NCT00707512

COMPLETED Phase 1

Administration of BIIB028 to Subjects With Solid Tumors

NCT00725933

COMPLETED Phase 1

A Phase I Study of BIIB015 in Relapsed/Refractory Solid Tumors

NCT00674947

COMPLETED Phase 2

A Phase 2 Study of Interferon Beta-1a (Avonex®) in Ulcerative Colitis

NCT00616434

COMPLETED Phase 2

Phase IIa Trial to Determine the Effects of Bardoxolone Methyl on Renal Function in Patients With Diabetic Nephropathy

NCT00664027

COMPLETED Phase 1

A Multiple Dose Safety Study of PEG-IFN in Healthy Volunteers

NCT02125578

COMPLETED

ATP Expression in Lymphocytes of MS Patients by Means of "ImmuKnow®" Assay.

NCT00618267

COMPLETED Phase 2

An Open-Label, 18FDG-PET Pharmacodynamic Assessment of the Effect of BIIB021 in Subjects With Gastrointestinal Stromal Tumors (GIST)

NCT00618319

COMPLETED Phase 1

Once or Twice Daily Administration of BIIB021 to Subjects With Advanced Solid Tumors

NCT00618735

TERMINATED Phase 2

Evaluation of Safety and Efficacy of Fludarabine, Cyclophosphamide, and Rituximab (FCR) +/- Lumiliximab in Subjects With Previously Untreated Chronic Lymphocytic Leukemia (CLL)

NCT00801060

COMPLETED Phase 4

The Effects of Tysabri Treatment on Vaccination Response and Lymphocyte Subsets in Subjects With Relapsing Forms of Multiple Sclerosis

NCT00536120

COMPLETED Phase 1

Phase 1 Study of BIIB022 (Anti-IGF-1R Monoclonal Antibody) in Relapsed/Refractory Solid Tumors

NCT00555724

COMPLETED Phase 1

CNF2024 (BIIB021) HER2- (QD) HER2+ (BIW w/Herceptin) PK/PD Study

NCT00412412

TERMINATED Phase 2

RTA 744 in Breast Cancer Patients With Progression of Previously Irradiated Brain Metastases

NCT00538343

COMPLETED Phase 1

Safety Study of Natalizumab to Treat Multiple Sclerosis (MS)

NCT00559702

TERMINATED Phase 1

Study With Gemcitabine and RTA 402 for Patients With Unresectable Pancreatic Cancer

NCT00529113

COMPLETED

Evaluation of Natalizumab for thE Relief of MS Associated FatiGue

NCT00464074

TERMINATED Phase 2

BG9924 in Combination With Methotrexate Extension of Study 104RA203 (NCT 00458861)

NCT00523328

COMPLETED Phase 3

Efficacy and Safety Study of Oral BG00012 With Active Reference in Relapsing-Remitting Multiple Sclerosis

NCT00451451

TERMINATED Phase 1

Study to Assess the Safety, Tolerability, and Pharmacodynamics of RTA 402 in Patients With Hepatic Dysfunction

NCT00550849

COMPLETED

Avonex 15 Year Long Term Follow-up Study

NCT00525343

TERMINATED Phase 2

BG9924 in Combination With Methotrexate for Participants With Active Rheumatoid Arthritis

NCT00458861

COMPLETED Phase 3

Efficacy and Safety of Oral BG00012 in Relapsing-Remitting Multiple Sclerosis

NCT00420212

COMPLETED

Pregnancy Exposure Registry for Tysabri®

NCT00472992

COMPLETED

TYSABRI Global Observational Program in Safety

NCT00477113

COMPLETED Early Phase 1

A Multicenter Study to Assess the Effect of Plasma Exchange in Accelerating the Clearance of Natalizumab in Subjects With Multiple Sclerosis (MS)

NCT00424788

TERMINATED Phase 2

Lumiliximab With Fludarabine, Cyclophosphamide, and Rituximab (FCR) Versus FCR Alone in Subjects With Relapsed Chronic Lymphocytic Leukemia (CLL)

NCT00391066

TERMINATED Phase 1

A Safety Study of RTA 744 in Recurrent, Progressive or Refractory Neoplastic Meningitis

NCT00527410

COMPLETED Phase 2

Natalizumab High Titer Immunogenicity and Safety

NCT00516893

TERMINATED Phase 2

Safety and Tolerability of Rituxan With Methotrexate and Etanercept or Methotrexate and Adalimumab in Patients With Active Rheumatoid Arthritis

NCT00298272

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What the Pipeline for Biogen Shows

According to the ClinicalTrials.gov registry, Biogen is linked to 334 US clinical trials across every stage of research activity. Of those, 21 studies are currently recruiting, about 6% of the sponsor's indexed portfolio, and 237 are already marked complete, representing roughly 71% of the total.

The phase mix for Biogen reports 84 late-stage studies (Phase 3 and Phase 4 combined) and 198 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for Biogen is Multiple Sclerosis with 13 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.