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NCT03070119 · ClinicalTrials.gov registry record · Phase 3

Long-Term Evaluation of BIIB067 (Tofersen)

A Phase 3 study, sponsored by Biogen.

Completed
Registry status
Phase 3
Development phase
139
Enrollment target

NCT03070119 is a Phase 3 study that has completed, run by Biogen. The registered enrollment target is 139 participants.

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The verdict

NCT03070119, a Phase 3 study, has completed, sponsored by Biogen.

COMPLETED
Registry status
Phase 3
Development phase
139 participants
Enrollment target

Study Summary

The primary objective of the study is to evaluate the long-term safety and tolerability of BIIB067 (tofersen) in participants with amyotrophic lateral sclerosis (ALS) and confirmed superoxide dismutase 1 (SOD1) mutation. The secondary objectives are to evaluate the pharmacokinetic (PK), pharmacodynamic (PD), biomarker effects, and efficacy of BIIB067 administered to participants with ALS and a confirmed SOD1 mutation.

Interventions

  • DRUG Tofersen

Trial Details

FieldValue
Enrollment Target 139 participants
Start Date 2017-03-08
Est. Completion 2024-08-12
Phase Phase 3

Sponsor

Biogen

334 total trials

What the Registry Record Tells You About NCT03070119

The ClinicalTrials.gov registry entry for NCT03070119 describes a study currently listed as completed, categorized as Phase 3. The registered enrollment target is 139 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Biogen, which has 334 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which Tofersen is the first listed.

NCT03070119 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT03070119 about?

NCT03070119 is a clinical study titled "Long-Term Evaluation of BIIB067 (Tofersen)". The primary objective of the study is to evaluate the long-term safety and tolerability of BIIB067 (tofersen) in participants with amyotrophic lateral sclerosis (ALS) and confirmed superoxide dismutase 1 (SOD1) mutation. The secondary objectives are to evaluate the pharmacokinetic (PK), pharmacodyna...

What is the current status of trial NCT03070119?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 139 participants. The study started on 2017-03-08. Estimated completion is 2024-08-12.

What interventions are being tested in trial NCT03070119?

The interventions under investigation include: Tofersen (DRUG).

Who is sponsoring clinical trial NCT03070119?

This trial is sponsored by Biogen, which has 334 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.