AstraZeneca

1,285 total trials 160 currently recruiting 883 completed

AstraZeneca sponsors 1,285 registered US clinical trials on ClinicalTrials.gov, 160 of them currently recruiting, and 883 completed. 484 of these trials are in Phase 3-4 (later-stage) and 720 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Non-Small Cell Lung Cancer, with 24 trials.

Trial Pipeline

1,285 total, page 10 of 26

TERMINATED Phase 1

Study of AZD0466 Monotherapy or in Combination in Patients With Advanced Haematological Malignancies

NCT04865419

COMPLETED

Estimation of the Prevalence of HER2 Low and Describe the SoC, Treatment Patterns, and Outcome in Real-world Practice Among Unresectable and/or Metastatic Breast Cancer Patients With HER2 Low Status

NCT04807595

TERMINATED Phase 3

Effect of Sodium Zirconium Cyclosilicate on Arrythmia-related Cardiovascular Outcomes in Participants on Chronic Hemodialysis With Recurrent Hyperkalemia (DIALIZE-Outcomes)

NCT04847232

COMPLETED Phase 2

Zibotentan and Dapagliflozin for the Treatment of CKD (ZENITH-CKD Trial)

NCT04724837

COMPLETED NA

Managing Asthma Patients With AMAZE™: A Novel Disease Management Platform

NCT04868500

COMPLETED Phase 3

Efficacy and Safety of Tezepelumab in Participants With Severe Chronic Rhinosinusitis With Nasal Polyposis

NCT04851964

COMPLETED NA

US PRECISION Implementation Study

NCT04891978

TERMINATED Phase 3

A Study to Investigate the Use of Benralizumab in Patients With Bullous Pemphigoid.

NCT04612790

TERMINATED Phase 3

Study of the Effect of SZC on Serum Potassium and Serum Bicarbonate in Patients With Hyperkalemia and Metabolic Acidosis Associated With Chronic Kidney Disease

NCT04727528

COMPLETED Phase 2

A Study of CIN-107 in Adults With Primary Aldosteronism

NCT04605549

COMPLETED Phase 4

Study to Assess Efficacy and Safety of SZC for the Management of High Potassium in Patients With Symptomatic HFrEF Receiving Spironolactone

NCT04676646

COMPLETED Phase 3

Study to Assess PT010 in Adult and Adolescent Participants With Inadequately Controlled Asthma (LOGOS)

NCT04609904

COMPLETED Phase 1

Study to Assess the Bioequivalence of Acalabrutinib Tablet and Acalabrutinib Capsule

NCT04768985

COMPLETED Phase 1

AZD4573 in Novel Combinations With Anti-cancer Agents in Patients With Advanced Blood Cancer

NCT04630756

COMPLETED Phase 3

Phase III Study of AZD7442 for Treatment of COVID-19 in Outpatient Adults

NCT04723394

COMPLETED Phase 2

Efficacy, Safety and Tolerability of AZD9977 and Dapagliflozin in Participants With Heart Failure and Chronic Kidney Disease

NCT04595370

COMPLETED Phase 1

Study to Evaluate the Pharmacokinetics of CIN-107 in Subjects With Varying Degrees of Renal Function

NCT05470725

COMPLETED Phase 3

Study to Assess PT010 in Adult and Adolescent Participants With Inadequately Controlled Asthma (KALOS)

NCT04609878

COMPLETED

REVEAL-CKD: Prevalence and Consequences of Undiagnosed Chronic Kidney Disease

NCT04847531

COMPLETED Phase 2

A Phase II, Randomized, Double-blind, Placebo-controlled Study to Assess MEDI3506 in Participants With COPD and Chronic Bronchitis

NCT04631016

COMPLETED Phase 3

Phase III Double-blind, Placebo-controlled Study of AZD7442 for Post- Exposure Prophylaxis of COVID-19 in Adults

NCT04625972

TERMINATED Phase 1

A Study of MEDI9253 in Combination With Durvalumab in Select Solid Tumors

NCT04613492

COMPLETED Phase 2

A Study Investigating DNA-damage Response Agents in Molecularly Altered Advanced Cancer

NCT04564027

COMPLETED Phase 2

A Study of Adavosertib as Treatment for Uterine Serous Carcinoma

NCT04590248

COMPLETED Phase 3

Phase III Study to Determine Efficacy of Durvalumab in Stage II-III Non-small Cell Lung Cancer (NSCLC) After Curative Intent Therapy.

NCT04642469

COMPLETED Phase 2

Study of Durvalumab Following Radiation Therapy in Patients With Stage 3 Unresectable NSCLC Ineligible for Chemotherapy

NCT04249362

COMPLETED

AMAZE™ Asthma Implementation QI Study

NCT04901260

COMPLETED Phase 3

Phase III Double-blind, Placebo-controlled Study of AZD7442 for Pre-exposure Prophylaxis of COVID-19 in Adult.

NCT04625725

COMPLETED Phase 1

Assessment of Safety, Tolerability, Immunogenicity, and Pharmacokinetics of AZD3427

NCT04630067

TERMINATED Phase 2

Efficacy and Safety Study of the Use of Benralizumab for Patients With Moderate to Severe Atopic Dermatitis

NCT04605094

COMPLETED Phase 1

A Study to Assess Safety, Tolerability, PK and PD of AZD2693 in Non-alcoholic Steatohepatitis Patients

NCT04483947

COMPLETED Phase 2

Efficacy and Safety of MEDI6570 in Patients With a History of Myocardial Infarction

NCT04610892

COMPLETED Phase 1

Study to Evaluate the Effect of CIN-107 on the Pharmacokinetics of the MATE Substrate, Metformin, in Healthy Subjects

NCT05526690

COMPLETED Phase 2

A Study of AZD8233 in Participants With Dyslipidemia

NCT04641299

TERMINATED Phase 2

A Study to Investigate the Use of Benralizumab in Patients With Chronic Spontaneous Urticaria Who Are Symptomatic Despite the Use of Antihistamines (ARROYO)

NCT04612725

COMPLETED

Patient Palatability and Preference of 3 Potassium Binders in Patients With Chronic Kidney Disease and Hyperkalaemia

NCT04566653

COMPLETED Phase 1

A Study to Assess Drug Absorption of Fixed Dose Combinations of Budesonide, Glycopyrronium, and Formoterol

NCT04600505

COMPLETED Phase 1

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics Study of AZD3366 in Healthy Subjects, Japanese and Chinese Subjects

NCT04588727

TERMINATED Phase 2

A Study to Evaluate the Safety and Efficacy of AZD5718 in Participants With Proteinuric Chronic Kidney Disease

NCT04492722

COMPLETED

Patient Characteristics, Persistence to Treatment and Outcome Events in Patients Treated With Ticagrelor 60 mg After Myocardial Infarction in Real-world Clinical Practice

NCT04568083

TERMINATED Phase 3

A Study of Benralizumab in Patients With Eosinophilic Esophagitis

NCT04543409

COMPLETED Phase 2

Study to Assess the Efficacy and Safety of MEDI3506 in Adults With Uncontrolled Moderate-to-severe Asthma

NCT04570657

COMPLETED Phase 3

Phase III Double-blind, Placebo-controlled Study of AZD1222 for the Prevention of COVID-19 in Adults

NCT04516746

COMPLETED Phase 2

Evaluate the Safety and Tolerability, for Nirsevimab in Immunocompromised Children

NCT04484935

COMPLETED Phase 1

First Time in Human Study of AZD8701 With or Without Durvalumab in Participants With Advanced Solid Tumours

NCT04504669

COMPLETED Phase 2

A Study of AZD4635 With Durvalumab and With Cabazitaxel and Durvalumab in Patients With mCRPC.

NCT04495179

COMPLETED Phase 1

Multiple Ascending Dose Study of MEDI1341 in Patients With Parkinson's Disease

NCT04449484

COMPLETED Phase 1

A Study to Evaluate the Safety and Pharmacokinetics With MEDI8367 Administered in Healthy Subjects, and in Subjects With Chronic Kidney Disease

NCT04365218

COMPLETED Phase 1

A Study to Evaluate Effects of Proton-pump Inhibitor on Acalabrutinib Capsule When Administered Orally With COCA-COLA in Healthy Participants

NCT04489797

COMPLETED Phase 3

Phase III Study to Determine the Efficacy of Durvalumab in Combination With Chemotherapy in Completely Resected Stage II-III Non-small Cell Lung Cancer (NSCLC)

NCT04385368

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Phase Distribution

PhaseTrial count
Phase 1 444
Phase 2 276
Phase 3 437
Phase 4 47

What the Pipeline for AstraZeneca Shows

According to the ClinicalTrials.gov registry, AstraZeneca is linked to 1,285 US clinical trials across every stage of research activity. Of those, 160 studies are currently recruiting, about 12% of the sponsor's indexed portfolio, and 883 are already marked complete, representing roughly 69% of the total.

The phase mix for AstraZeneca reports 484 late-stage studies (Phase 3 and Phase 4 combined) and 720 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for AstraZeneca is Non-Small Cell Lung Cancer with 24 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.