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Chronic Obstructive Pulmonary Disease (COPD)
Open-data reference.
35 US clinical trials · 10 currently recruiting
Active & Recent Trials
Collection of Airway, Blood and/or Urine Specimens From Subjects for Research Studies
Weill Medical College of Cornell University
NCT01776398
A Study to Evaluate Astegolimab in Participants With Chronic Obstructive Pulmonary Disease
Hoffmann-La Roche
NCT05595642
A Study to Investigate the Effect of AZD6793 in Participants With Moderate to Very Severe Chronic Obstructive Pulmonary Disease
AstraZeneca
NCT07082738
Temple Health Chest Initiative (THCI 2.0)
Temple University
NCT06933758
A Study to Investigate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe COPD (D5241C00007)
AstraZeneca
NCT06878261
A Study to Investigate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe COPD (D5241C00006)
AstraZeneca
NCT06883305
Multi-Center Clean Air Randomized Controlled Trial in COPD
JHSPH Center for Clinical Trials
NCT06376994
Clinical Trial of Omalizumab for Allergen Sensitized and Exposed Individuals With COPD
Johns Hopkins University
NCT07059091
Effectiveness of the WearME System for COPD Severity and Respiratory Function
LASARRUS Clinic and Research Center
NCT06751537
Functional Social Support in COPD Self-Management
Medical University of South Carolina
NCT07353034
Long-term Efficacy and Safety of Tozorakimab in Participants With Chronic Obstructive Pulmonary Disease With a History of Exacerbations (PROSPERO).
AstraZeneca
NCT05742802
Efficacy and Safety of Tozorakimab in Symptomatic Chronic Obstructive Pulmonary Disease With a History of Exacerbations
AstraZeneca
NCT06040086
Efficacy and Safety of Tozorakimab in Symptomatic Chronic Obstructive Pulmonary Disease With a History of Exacerbations.
AstraZeneca
NCT05158387
Efficacy and Safety of Tozorakimab in Symptomatic Chronic Obstructive Pulmonary Disease With a History of Exacerbations
AstraZeneca
NCT05166889
The CAPTURE Study: Validating a Unique COPD Case Finding Tool in Primary Care (Aim 3)
Weill Medical College of Cornell University
NCT03583099
Efficacy and Safety of Indacaterol Plus Tiotropium Versus Tiotropium Alone in Patients With Chronic Obstructive Pulmonary Disease
Novartis Pharmaceuticals
NCT00877383
A Long-Term Safety Trial of Treatment With Nebulized SUN-101 in Patients With COPD
Sunovion Respiratory Development
NCT02276222
A 52-Week Parallel Group Safety Study of TD-4208 in Chronic Obstructive Pulmonary Disease (COPD)
Mylan
NCT02518139
A 12 Week Treatment, Multi-center, Randomized, Double-blind, Parallel-group, Placebo and Active Controlled Study to Assess the Efficacy, Safety, and Tolerability of Indacaterol Maleate / Glycopyrronium Bromide in COPD Patients With Moderate to Severe Airflow Limitation.
Novartis Pharmaceuticals
NCT01727141
Efficacy Study of Nebulized TD-4208 for Chronic Obstructive Pulmonary Disease (COPD)
Mylan
NCT02512510
Open-Label Assessment of the Albuterol Spiromax® Dry Powder Inhaler (DPI)
Teva Branded Pharmaceutical Products R&D
NCT01857323
Stepping up to Health - for Veterans With Chronic Obstructive Pulmonary Disease (COPD)
VA Office of Research and Development
NCT01102777
Safety and Tolerability of 28 Days Treatment With Glycopyrronium Bromide (NVA237) (100 or 200 µg Once a Day) in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease
Novartis
NCT00510510
Aides in Respiration Health Coaching for COPD
University of California, San Francis
NCT02234284
A Phase II, Randomized, Double-blind, Placebo-controlled Study to Assess MEDI3506 in Participants With COPD and Chronic Bronchitis
AstraZeneca
NCT04631016
Tiotropium Bromide Inhalation Solution in Subjects With Chronic Obstructive Pulmonary Disease
Nephron Pharmaceuticals Corporation
NCT04780984
Use of Respiratory Therapists (RTs) to Improve Outcomes and Quality of Life in Patients With COPD
StratiHealth
NCT02078622
Tai Chi After Pulmonary Rehabilitation in Patients With COPD: A Randomized Trial
Beth Israel Deaconess Medical Center
NCT01998724
Sodium Pyruvate Therapy in COPD Patients
Emphy
NCT00262613
A Study to Assess Drug Absorption of Fixed Dose Combinations of Budesonide, Glycopyrronium, and Formoterol
AstraZeneca
NCT04600505
Effect of Supplementary Vitamins on Oxidant Gene Expression in the Lungs of Healthy Smokers
Weill Medical College of Cornell University
NCT00565214
A Clinical Study to Investigate if a Single Dose of an Approved Drug Product (Glycopyrrolate Inhalation Solution) Reduces Trapped Air in the Lungs of Participants With Chronic Obstructive Pulmonary Disease.
Sunovion Respiratory Development
NCT04155047
Ex-vivo Perfusion and Ventilation of Lungs Recovered From Non-Heart-Beating Donors to Assess Transplant Suitability
University of North Carolina, Chapel Hill
NCT01615484
Evaluation of Auto-EPAP for Management of Upper Airway Obstruction During Non-Invasive Ventilation
Breas Medical
NCT06560411
Safety Study of CTX-100 Inhalation Solution (Formerly ETX-100)
Turino, Gerard, M.D.
NCT00993707
Phase Distribution
| Phase | Trial count |
|---|---|
| Early Phase 1 | 1 |
| Phase 2 | 7 |
| Phase 3 | 14 |
| Phase 4 | 1 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Chronic Obstructive Pulmonary Disease (COPD) Trial Landscape
ClinicalTrials.gov lists 35 US studies indexed under Chronic Obstructive Pulmonary Disease (COPD), and 10 of those are currently open to recruitment — roughly 29% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Chronic Obstructive Pulmonary Disease (COPD) shows 15 late-stage studies (Phase 3 and Phase 4 combined) alongside 8 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Chronic Obstructive Pulmonary Disease (COPD) is led by AstraZeneca with 9 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 35 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Chronic Obstructive Pulmonary Disease (COPD)?
PlainTrial tracks 35 US clinical trials for Chronic Obstructive Pulmonary Disease (COPD), of which 10 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Chronic Obstructive Pulmonary Disease (COPD)?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.