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ClinicalTrials.gov 11 recruiting now later-stage tilt

Chronic Obstructive Pulmonary Disease (COPD): later-stage trial registry

11 of 37 indexed Chronic Obstructive Pulmonary Disease (COPD) trials are currently recruiting, with more weight in Phase 3-4.

Corpus placement: #406 of 28,707 conditions by registered trial count.

37 US clinical trials · 11 currently recruiting · #406 of 28,707 conditions by registered trial count

Chronic Obstructive Pulmonary Disease (COPD): 37 US clinical trials tracked, 11 recruiting.

Chronic Obstructive Pulmonary Disease (COPD) is the subject of 37 registered US clinical trials on ClinicalTrials.gov, 11 of them currently open to new participants. 16 are in Phase 3-4 (later-stage) and 8 in Phase 1-2 (earlier-stage). The most active sponsor is AstraZeneca, running 10 of these trials.

Enrollment posture brief

Registry condition chronic-obstructive-pulmonary-disease-copd

OPEN 11 | RECR 30% | LATE 16 | EARLY 8 | RANK #406 | SPON 10

Nearest open-share peer: Substance-Related Disorders (30% recruiting · 64 trials)

Biliary Tract Cancer64.9%Breastfeeding45.9%Graft Vs Host Disease32.4%Chronic Obstructive Pulm (th…30%Burns24.3%
Open-enrollment share among volume-matched conditions near Chronic Obstructive Pulmonary Disease (COPD)

Chronic Obstructive Pulmonary Disease (COPD) lists 11 open slots (30% of 37 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Chronic Obstructive Pulmonary Disease (COPD) on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Chronic Obstructive Pulmonary Disease (COPD) is recruiting below its size-band peers.

    11 of 37 indexed trials (29.7%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Chronic Obstructive Pulmonary Disease (COPD) research.

    AstraZeneca accounts for 10 of 37 trials (27%). 23 distinct sponsors appear on at least one study for this condition label.

  3. Typical Chronic Obstructive Pulmonary Disease (COPD) enrolment sits around 317 participants.

    Median target enrolment is 317 among the 37 trials that report a genuine target (sentinel values excluded). 8 of those (21.6%) plan for fewer than 100 participants.

  4. Chronic Obstructive Pulmonary Disease (COPD) research is mostly interventional.

    32 interventional and 5 observational studies make up this index (86.5% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 11Phase 27Phase 314Phase 42

Open and recent trials

37 total, page 1 of 1

RECRUITING 2,000 participants

Collection of Airway, Blood and/or Urine Specimens From Subjects for Research Studies

Weill Medical College of Cornell University

NCT01776398

RECRUITING Phase 3 1,290 participants

A Study to Evaluate Astegolimab in Participants With Chronic Obstructive Pulmonary Disease

Hoffmann-La Roche

NCT05595642

RECRUITING Phase 2 1,160 participants

A Study to Investigate the Effect of AZD6793 in Participants With Moderate to Very Severe Chronic Obstructive Pulmonary Disease

AstraZeneca

NCT07082738

RECRUITING 1,000 participants

Temple Health Chest Initiative (THCI 2.0)

Temple University

NCT06933758

RECRUITING Phase 3 990 participants

A Study to Investigate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe COPD (D5241C00007)

AstraZeneca

NCT06878261

RECRUITING Phase 3 990 participants

A Study to Investigate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe COPD (D5241C00006)

AstraZeneca

NCT06883305

RECRUITING Phase 3 770 participants

Multi-Center Clean Air Randomized Controlled Trial in COPD

JHSPH Center for Clinical Trials

NCT06376994

RECRUITING Phase 2 334 participants

Clinical Trial of Omalizumab for Allergen Sensitized and Exposed Individuals With COPD

Johns Hopkins University

NCT07059091

RECRUITING NA 306 participants

Pulmonary Rehabilitation for Rural Patients With COPD

Mayo Clinic

NCT06847061

RECRUITING 128 participants

Effectiveness of the WearME System for COPD Severity and Respiratory Function

LASARRUS Clinic and Research Center

NCT06751537

RECRUITING 111 participants

Functional Social Support in COPD Self-Management

Medical University of South Carolina

NCT07353034

ACTIVE NOT RECRUITING Phase 3 1,713 participants

Long-term Efficacy and Safety of Tozorakimab in Participants With Chronic Obstructive Pulmonary Disease With a History of Exacerbations (PROSPERO).

AstraZeneca

NCT05742802

ACTIVE NOT RECRUITING Phase 3 1,454 participants

Efficacy and Safety of Tozorakimab in Symptomatic Chronic Obstructive Pulmonary Disease With a History of Exacerbations

AstraZeneca

NCT06040086

ACTIVE NOT RECRUITING Phase 3 1,172 participants

Efficacy and Safety of Tozorakimab in Symptomatic Chronic Obstructive Pulmonary Disease With a History of Exacerbations.

AstraZeneca

NCT05158387

ACTIVE NOT RECRUITING Phase 3 1,132 participants

Efficacy and Safety of Tozorakimab in Symptomatic Chronic Obstructive Pulmonary Disease With a History of Exacerbations

AstraZeneca

NCT05166889

COMPLETED NA 2,004 participants

The CAPTURE Study: Validating a Unique COPD Case Finding Tool in Primary Care (Aim 3)

Weill Medical College of Cornell University

NCT03583099

COMPLETED Phase 3 1,142 participants

Efficacy and Safety of Indacaterol Plus Tiotropium Versus Tiotropium Alone in Patients With Chronic Obstructive Pulmonary Disease

Novartis Pharmaceuticals

NCT00877383

COMPLETED Phase 3 1,087 participants

A Long-Term Safety Trial of Treatment With Nebulized SUN-101 in Patients With COPD

Sunovion Respiratory Development

NCT02276222

COMPLETED Phase 3 1,060 participants

A 52-Week Parallel Group Safety Study of TD-4208 in Chronic Obstructive Pulmonary Disease (COPD)

Mylan

NCT02518139

COMPLETED Phase 3 1,042 participants

A 12 Week Treatment, Multi-center, Randomized, Double-blind, Parallel-group, Placebo and Active Controlled Study to Assess the Efficacy, Safety, and Tolerability of Indacaterol Maleate / Glycopyrronium Bromide in COPD Patients With Moderate to Severe Airflow Limitation.

Novartis Pharmaceuticals

NCT01727141

COMPLETED Phase 3 611 participants

Efficacy Study of Nebulized TD-4208 for Chronic Obstructive Pulmonary Disease (COPD)

Mylan

NCT02512510

COMPLETED Phase 3 317 participants

Open-Label Assessment of the Albuterol Spiromax® Dry Powder Inhaler (DPI)

Teva Branded Pharmaceutical Products R&D

NCT01857323

COMPLETED NA 307 participants

Stepping up to Health - for Veterans With Chronic Obstructive Pulmonary Disease (COPD)

VA Office of Research and Development

NCT01102777

COMPLETED Phase 2 281 participants

Safety and Tolerability of 28 Days Treatment With Glycopyrronium Bromide (NVA237) (100 or 200 µg Once a Day) in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease

Novartis

NCT00510510

COMPLETED NA 192 participants

Aides in Respiration Health Coaching for COPD

University of California, San Francisco

NCT02234284

COMPLETED Phase 4 138 participants

Adherence Study in COPD Patients

AstraZeneca

NCT02864342

COMPLETED Phase 2 137 participants

A Phase II, Randomized, Double-blind, Placebo-controlled Study to Assess MEDI3506 in Participants With COPD and Chronic Bronchitis

AstraZeneca

NCT04631016

COMPLETED Phase 2 116 participants

Tiotropium Bromide Inhalation Solution in Subjects With Chronic Obstructive Pulmonary Disease

Nephron Pharmaceuticals Corporation

NCT04780984

COMPLETED 114 participants

Use of Respiratory Therapists (RTs) to Improve Outcomes and Quality of Life in Patients With COPD

StratiHealth

NCT02078622

COMPLETED NA 90 participants

Tai Chi After Pulmonary Rehabilitation in Patients With COPD: A Randomized Trial

Beth Israel Deaconess Medical Center

NCT01998724

COMPLETED Phase 2 60 participants

Sodium Pyruvate Therapy in COPD Patients

Emphy

NCT00262613

COMPLETED Phase 1 47 participants

A Study to Assess Drug Absorption of Fixed Dose Combinations of Budesonide, Glycopyrronium, and Formoterol

AstraZeneca

NCT04600505

COMPLETED NA 46 participants

Effect of Supplementary Vitamins on Oxidant Gene Expression in the Lungs of Healthy Smokers

Weill Medical College of Cornell University

NCT00565214

COMPLETED Phase 4 44 participants

A Clinical Study to Investigate if a Single Dose of an Approved Drug Product (Glycopyrrolate Inhalation Solution) Reduces Trapped Air in the Lungs of Participants With Chronic Obstructive Pulmonary Disease.

Sunovion Respiratory Development

NCT04155047

COMPLETED NA 24 participants

Ex-vivo Perfusion and Ventilation of Lungs Recovered From Non-Heart-Beating Donors to Assess Transplant Suitability

University of North Carolina, Chapel Hill

NCT01615484

COMPLETED NA 23 participants

Evaluation of Auto-EPAP for Management of Upper Airway Obstruction During Non-Invasive Ventilation

Breas Medical

NCT06560411

COMPLETED Phase 2 11 participants

Safety Study of CTX-100 Inhalation Solution (Formerly ETX-100)

Turino, Gerard, M.D.

NCT00993707

Phase Distribution

PhaseTrial count
Phase 1 1
Phase 2 7
Phase 3 14
Phase 4 2

Named interventions

Most-linked intervention names on Chronic Obstructive Pulmonary Disease (COPD) records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Placebo Drug
8 trials
Tozorakimab Drug
4 trials
Placebo Other
4 trials
TD-4208 Drug
2 trials
Tezepelumab Biological
2 trials
Arm 2: BreatheMate device without application Device
1 trials
Arm 1: BreatheMate device with application Device
1 trials
NVA237 200 µg Drug
1 trials

US sites by state

Facility locations filed on Chronic Obstructive Pulmonary Disease (COPD) trials. A trial with sites in several states counts in each.

California 20 trials
Arizona 16 trials
Florida 15 trials
Alabama 14 trials
Colorado 10 trials
South Carolina 8 trials
Maryland 8 trials
New York 7 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Chronic Obstructive Pulmonary Disease (COPD) page

37 registered trials, 11 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 11 Chronic Obstructive Pulmonary Disease (COPD) trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • AstraZeneca sponsors the most Chronic Obstructive Pulmonary Disease (COPD) trials on record, review their full trial history before evaluating a specific study. See AstraZeneca's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Chronic Obstructive Pulmonary Disease (COPD) condition card totals 37 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.