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NCT04630067 · ClinicalTrials.gov registry record · Phase 1
Assessment of Safety, Tolerability, Immunogenicity, and Pharmacokinetics of AZD3427
A Phase 1 study, sponsored by AstraZeneca.
- Completed
- Registry status
- Phase 1
- Development phase
- 105
- Enrollment target
NCT04630067: Completed Phase 1 study, sponsored by AstraZeneca.
NCT04630067 is a Phase 1 study that has completed, run by AstraZeneca. The registered enrollment target is 105 participants, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (75% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04630067, a Phase 1 study, has completed, sponsored by AstraZeneca.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 105 participants
- Enrollment target
Study Summary
This first-time-in-human (FTIH) study will be conducted to evaluate the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD), and immunogenicity of single doses of AZD3427 in healthy volunteers and multiple doses of AZD3427 in patients with heart failure (HF).
Primary Outcome
Assessment of the safety and tolerability of single and multiple ascending doses of AZD3427.
Interventions
- DRUG Placebo
- DRUG AZD3427
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 105 participants |
| Start Date | 2020-11-17 |
| Est. Completion | 2022-09-14 |
| Phase | Phase 1 |
What the finished NCT04630067 record still lists
NCT04630067 is an interventional study that assigns participants to a tested intervention. The registered 105 participants enrollment target is mid-sized for trials with a published cap, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (75% higher).
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT04630067 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04630067 about?
NCT04630067 is a clinical study titled "Assessment of Safety, Tolerability, Immunogenicity, and Pharmacokinetics of AZD3427". This first-time-in-human (FTIH) study will be conducted to evaluate the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD), and immunogenicity of single doses of AZD3427 in healthy volunteers and multiple doses of AZD3427 in patients with heart failure (HF).
What is the current status of trial NCT04630067?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 105 participants. The study started on 2020-11-17. Estimated completion is 2022-09-14.
What interventions are being tested in trial NCT04630067?
The interventions under investigation include: Placebo (DRUG), AZD3427 (DRUG).
Who is sponsoring clinical trial NCT04630067?
This trial is sponsored by AstraZeneca, which has 1,285 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04630067's enrollment target sits among peer trials
105 533rd of 2000 higher than 1,465 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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