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NCT04630756 · ClinicalTrials.gov registry record · Phase 1

AZD4573 in Novel Combinations With Anti-cancer Agents in Patients With Advanced Blood Cancer

A Phase 1 study of Advanced Haematological Malignancies, sponsored by AstraZeneca.

Completed
Registry status
Phase 1
Development phase
40
Enrollment target
17
Study locations

NCT04630756 is a Phase 1 study of Advanced Haematological Malignancies that has completed, run by AstraZeneca. The registered enrollment target is 40 participants. The trial reports 17 study locations across 5 states.

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The verdict

NCT04630756, a Phase 1 study of Advanced Haematological Malignancies, has completed, sponsored by AstraZeneca.

COMPLETED
Registry status
Phase 1
Development phase
40 participants
Enrollment target
17
Study locations

Study Summary

This is a modular, multicentre, open-label, non-randomised, Phase I/II, dose-setting and expansion study including an intra-participants dose ramp up. AZD4573 will be administered intravenously, in novel combinations with anti-cancer agents, to participants with relapsed/refractory (r/r) haematological malignancies.

Interventions

  • DRUG Acalabrutinib
  • DRUG AZD4573

Study Locations (17)

Other

  • Research Site - Clayton
  • Research Site - Nedlands
  • Research Site - Lille
  • Research Site - Dublin
  • Research Site - Galway
  • Research Site - Krakow
  • Research Site - Seoul
  • Research Site - Seoul
  • Research Site - Seoul
  • Research Site - Barcelona
  • Research Site - Palma de Mallorca
  • Research Site - Plymouth

California

  • Research Site - Duarte
  • Research Site - La Jolla

Texas

  • Research Site - Houston

Utah

  • Research Site - Salt Lake City

Quebec

  • Research Site - Québec

Trial Details

FieldValue
Enrollment Target 40 participants
Start Date 2021-02-17
Est. Completion 2025-02-27
Phase Phase 1

Sponsor

AstraZeneca

1,285 total trials

What the Registry Record Tells You About NCT04630756

The ClinicalTrials.gov registry entry for NCT04630756 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 40 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is AstraZeneca, which has 1,285 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Advanced Haematological Malignancies appearing as the primary indexed condition, and to 2 interventions - of which Acalabrutinib is the first listed.

NCT04630756 reports 17 study locations spanning 5 distinct geographic areas - top geographies include Other, California, Texas.

Frequently Asked Questions

What is clinical trial NCT04630756 about?

NCT04630756 is a clinical study titled "AZD4573 in Novel Combinations With Anti-cancer Agents in Patients With Advanced Blood Cancer". This is a modular, multicentre, open-label, non-randomised, Phase I/II, dose-setting and expansion study including an intra-participants dose ramp up. AZD4573 will be administered intravenously, in novel combinations with anti-cancer agents, to participants with relapsed/refractory (r/r) haematologi...

What is the current status of trial NCT04630756?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 40 participants. The study started on 2021-02-17. Estimated completion is 2025-02-27.

What conditions does trial NCT04630756 study?

This clinical trial studies the following conditions: Advanced Haematological Malignancies.

What interventions are being tested in trial NCT04630756?

The interventions under investigation include: Acalabrutinib (DRUG), AZD4573 (DRUG).

Who is sponsoring clinical trial NCT04630756?

This trial is sponsored by AstraZeneca, which has 1,285 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04630756 being conducted?

This trial has 17 study locations across California, Texas, Utah, Quebec. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.