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ClinicalTrials.gov 24,857 recruiting now free trial finder

Find a clinical trial that's recruiting now

Search 24,857 actively recruiting US clinical trials by condition, drug, or state, each entry links straight to its NIH ClinicalTrials.gov record so you can check eligibility and contact the study team.

24,857
trials recruiting now
14%
of all US trials open to enrollment
52
states with recruiting sites

A trial is listed as recruiting when its sponsor has marked it open to new participants on the public registry. Type a condition or drug name (for example, "breast cancer" or "pembrolizumab") to narrow the list, and add a state to find studies with a site near you. Results are ordered with the most relevant recruiting studies first; each card shows the study phase and enrollment target, and opens the full record, including eligibility criteria and contact details, on ClinicalTrials.gov.

100 trials found

Recruiting 2,000,000 target

Helix Research Network

Helix

NCT06057181

Recruiting NA 21,350 target

Implementation Supports for Improving Identification and Delivery of School-based Mental Health Supports for Middle Schools Students

University of Virginia

NCT06047041

Recruiting 20,000 target

Exactech Shoulder Post Market Clinical Follow-up Study

Exactech

NCT05603728

Recruiting Phase 3 7,600 target

Preventing Alzheimer's With Cognitive Training

University of South Florida

NCT03848312

Recruiting 7,000 target

cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease

Adela

NCT05366881

Recruiting Phase 4 6,000 target

PREvention of CardIovascular and DiabEtic kidNey Disease in Type 2 Diabetes

Brigham and Women's Hospital

NCT05390892

Recruiting 5,000 target

Collection of Tissue Samples for Cancer Research

National Cancer Institute (NCI)

NCT00900198

Recruiting 4,400 target

Blue Light Cystoscopy With Cysview® Registry

Photocure

NCT02660645

Recruiting Phase 3 4,390 target

A Clinical Study of MK-8527 to Prevent Human Immunodeficiency Virus Type 1 (HIV-1) (MK-8527-011)

Merck Sharp & Dohme

NCT07044297

Recruiting NA 4,000 target

Pragmatic Trial to Enhance Quality Safety, and Patient Experience in COPD

Seattle Institute for Biomedical and Clinical Research

NCT05718102

Recruiting 3,000 target

Rett Syndrome Registry

International Rett Syndrome Foundation

NCT05432349

Recruiting NA 2,894 target

Healing, Equity, Advocacy and Respect for Mamas

Medical University of South Carolina

NCT06273436

Recruiting 2,500 target

Total Shoulder Arthroplasty Multi-Center Registry

Arthrex

NCT03511586

Recruiting 2,000 target

HF2 Registry - Hemodynamic Frontiers in Heart Failure Registry

University of Kansas Medical Center

NCT06425848

Recruiting 2,000 target

Multi-Center Molecular Diagnosis and Host Response of Respiratory Viral Infections in Pediatric Transplant Recipients

Arkansas Children's Hospital Research Institute

NCT05550298

Recruiting 2,000 target

A Prospective Real World Evidence Study (PROWES) for Concordance Rate of Blood-based 3D Genome Conformation Mapping (Episwitch CiRT®) to Identify Likelihood of Response and Actual Response Rates to PD-(L)-1 Checkpoint Inhibitors Across Multiple Oncological Indications.

Oxford Biodynamics

NCT06635954

Recruiting 2,000 target

Black and African Americans Connections to Parkinson's Disease (BLAAC PD)

Michael J. Fox Foundation for Parkinson's Research

NCT06719583

Recruiting 2,000 target

Pancreatic Cancer Detection Consortium

City of Hope Medical Center

NCT06388967

Recruiting NA 2,000 target

VALOR: Vaginal Atrophy & Long-term Observation of Recovery

Stratpharma

NCT05953090

Recruiting 2,000 target

Specimen Collection from Pregnant Women At Increased Risk for Fetal Aneuploidy

Sequenom

NCT01429389

Recruiting Phase 3 1,900 target

REVEAL Study - Diagnostic Testing for PTSD Using the Senseye Diagnostic Tool

Senseye

NCT07280065

Recruiting Phase 3 1,800 target

Efficacy and Safety of KAI-9531 in Participants Living With Obesity or Overweight With Weight-Related Comorbidities Who Do Not Have Diabetes

Kailera

NCT07284875

Recruiting Phase 3 1,700 target

Efficacy and Safety of KAI-9531 Administered Once Weekly in Participants Living With Obesity or Overweight and Diabetes

Kailera

NCT07284901

Recruiting Phase 4 1,572 target

DECIDE: A Comparative Effectiveness Trial of Metformin Versus Insulin for the Treatment of Gestational Diabetes

Ohio State University

NCT06445946

Recruiting 1,500 target

Pulmonary Hemodynamics During Exercise - Research Network

Medical University of Graz

NCT03954574

Recruiting NA 1,316 target

The Impact of MeMed BV® on Management of Patients With Suspected Lower Respiratory Tract Infections (LRTI) in the Emergency Department (ED) and Urgent Care Center (UCC) ("JUPITER" TRIAL)

MeMed Diagnostics

NCT05762302

Recruiting NA 1,305 target

The Active Mind Trial: An Adaptive Randomized Trial to Improve Function and Delay Dementia

University of Alabama at Birmingham

NCT04171323

Recruiting Phase 3 1,300 target

A Clinical Study to Evaluate the Safety, Tolerability, and Immunogenicity of VAX-31 With Influenza Vaccine in Adults ≥ 50 Years of Age

Vaxcyte

NCT07365826

Recruiting Phase 3 1,200 target

Efficacy and Safety of KAI-9531 Administered Once Weekly Compared With Semaglutide and Placebo in Participants Living With Obesity Who Do Not Have Diabetes

Kailera

NCT07284979

Recruiting NA 1,200 target

Feasibility and Efficacy Study of the CardioPulmonary Management (CPM) System in Patients With Chronic Heart Failure

Analog Device

NCT05650541

Recruiting Phase 1 1,200 target

Study of Pembrolizumab (MK-3475) Combination Therapies in Metastatic Castration-Resistant Prostate Cancer (MK-3475-365/KEYNOTE-365)

Merck Sharp & Dohme

NCT02861573

Recruiting Phase 3 1,150 target

AMAZE 1: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight Lose Weight

Novo Nordisk A/S

NCT07339423

Recruiting 1,051 target

A Study to Estimate How Often Post-stroke Spasticity Occurs and to Provide a Standard Guideline on the Best Way to Monitor Its Development

Ipsen

NCT06055725

Recruiting NA 1,040 target

Hyperhydration in Children With Shiga Toxin-Producing E. Coli Infection

University of Calgary

NCT05219110

Recruiting NA 1,024 target

iAmHealthy Clinical Practice Guideline (CPG)

University of Kansas Medical Center

NCT06888011

Recruiting 1,000 target

Testing Tumor Tissue and Blood to Help Select Personalized Treatments for Patients With Suspected Lung Cancers

Lung Cancer Mutation Consortium

NCT04712877

Recruiting 1,000 target

Beat Childhood Cancer Specimen Banking and Data Registry

Giselle Sholler

NCT04715178

Recruiting 1,000 target

Prospective Registry of Patients Undergoing Cardiac CT With NAEOTOM Alpha PCD-CT Before TAVI Procedure

Semmelweis University

NCT07016477

Recruiting 1,000 target

Pivotal Study for the Cardiac Performance System (CPS)

Sensydia Corporation

NCT06870591

Recruiting 1,000 target

A Post-Market Domestic (US) and International Data Collection to Assess the Truliant Knee System

Exactech

NCT05653102

Recruiting 1,000 target

Galvanize Prospective/Retrospective Pulsed Electric Field Device Registry

Galvanize Therapeutics

NCT05851430

Recruiting 1,000 target

Prevent Cancer- Greenville

Prisma Health-Upstate

NCT04947098

Recruiting Phase 3 981 target

Depemokimab as an Extended treatmeNt Duration Biologic in Adults With Chronic Obstructive Pulmonary Disease (COPD) and Type 2 Inflammation (ENDURA -1)

GlaxoSmithKline

NCT06959095

Recruiting Phase 2 960 target

A Study to Evaluate the Immune Response and Safety of an Influenza Vaccine in Adults 18 Years of Age and Above

GlaxoSmithKline

NCT07204964

Recruiting Phase 3 940 target

Study Comparing AAA817+ARPI Versus Standard of Care in Adult Participants With PSMA-positive mCRPC

Novartis Pharmaceuticals

NCT06855277

Recruiting 800 target

FebriDx® Pediatric Validation Study

Lumos Diagnostics

NCT07211997

Recruiting Phase 3 800 target

A Study of Pasritamig With Docetaxel Versus Docetaxel in Participants With Metastatic Castration-Resistant Prostate Cancer

Janssen Research & Development

NCT07225946

Recruiting NA 750 target

A Peer Recovery Coaching Intervention for Hospitalized Alcohol Use Disorder Patients

Clemson University

NCT06479681

Recruiting 750 target

Systemic Lupus Erythematosus in Gullah Health

Medical University of South Carolina

NCT00756769

Recruiting Phase 3 750 target

A Surveillance Study of Susceptibility to Baloxavir Marboxil in Pediatric Participants With Influenza and Transmission of Influenza to Household Contacts

Hoffmann-La Roche

NCT06094010

Recruiting Phase 2 744 target

Comparability Trial of the MVA-BN Vaccine Manufactured in Different Production Cells

Bavarian Nordic

NCT07199569

Recruiting Phase 3 726 target

Study of TDXd, Chemotherapy, Pembrolizumab, and Trastuzumab in First-Line Metastatic HER2-Positive Gastric or Gastroesophageal Junction Cancer

Daiichi Sankyo

NCT06731478

Recruiting Phase 3 705 target

A Study of Orelabrutinib in Patients With Primary Progressive Multiple Sclerosis

Zenas BioPharma (USA)

NCT07067463

Recruiting NA 702 target

Melodi Matrix™ in Breast Reconstruction

Melodi Health

NCT06027996

Recruiting 700 target

Advanced SPinal Innovations With Robotics and Enabling Technology Registry

Boston Children's Hospital

NCT05071144

Recruiting NA 700 target

ELEVATE-HFpEF Clinical Study

Medtronic Cardiac Rhythm and Heart Failure

NCT06678841

Recruiting NA 693 target

Evaluating the Auricular Point Acupressure-Self Management Program for Chronic Musculoskeletal Pain Among Rural Populations

The University of Texas Health Science Center, Houston

NCT07179016

Recruiting 680 target

A Non-interventional, Post-authorisation Safety Study of Patients Treated With Efgartigimod Alfa

argenx

NCT06298565

Recruiting 678 target

Safety and Efficacy of Workflows of High Volume Single Operators in a LAAO Device Implant Procedural Day

Heart Rhythm Clinical and Research Solutions

NCT06436924

Recruiting NA 675 target

Health Education Approach to Lung Screening

Virginia Commonwealth University

NCT06070870

Recruiting NA 672 target

Enhancing Smoking Cessation Via Telehealth Options in Primary Care

Medical University of South Carolina

NCT05493254

Recruiting Phase 2 666 target

A Study to Assess the Efficacy and Safety of Verekitug in Participants With COPD

Upstream Bio

NCT06981078

Recruiting Phase 3 663 target

A Study of Pasritamig Versus Placebo in Late Line Metastatic Castration-resistant Prostate Cancer (mCRPC)

Janssen Research & Development

NCT07164443

Recruiting Phase 3 662 target

A Study of Pirtobrutinib (LOXO-305) Versus Ibrutinib in Participants With Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL)

Loxo Oncology

NCT05254743

Recruiting Phase 3 644 target

Optimizing Pain Treatment in Children On Mechanical Ventilation

Weill Medical College of Cornell University

NCT06994442

Recruiting Phase 2 630 target

Study of Datopotamab Deruxtecan Plus Carboplatin or Cisplatin Versus Gemcitabine Plus Carboplatin or Cisplatin in Participants With Locally Advanced or Metastatic Urothelial Carcinoma

Daiichi Sankyo

NCT07129993

Recruiting 626 target

A Multicenter, Postmarket Surveillance Study of Subjects With the Canary canturioTM te Tibial Extension

Canary Medical

NCT06040827

Recruiting Phase 3 620 target

Fibromyalgia Response With Esreboxetine Evaluated Using a Randomized Withdrawal Research Design

Axsome Therapeutics

NCT07398417

Recruiting NA 616 target

Optimal Digital Weight Loss Treatment for Rural Individuals

University of South Carolina

NCT06105957

Recruiting NA 610 target

Treatment in Thoracic Aortic Aneurysm: Surgery vs Surveillance

Ottawa Heart Institute Research Corporation

NCT03536312

Recruiting NA 600 target

SAVE-FistulaS: the SelfWrap-Assisted ArterioVEnous Fistulas Study

VenoStent

NCT06001827

Recruiting Phase 4 600 target

De-implementing Inhaled Nitric Oxide for Congenital Diaphragmatic Hernia

The University of Texas Health Science Center, Houston

NCT05213676

Recruiting NA 600 target

Comparing Telephone Symptom Monitoring Interventions for Managing Symptoms and Psychological Distress During Oral Anti-Cancer Treatment

NRG Oncology

NCT06279013

Recruiting Phase 3 600 target

Intravitreal Faricimab Injections or Fluocinolone Acetonide (0.19 mg) Intravitreal Implants vs Observation for Prevention of VA Loss Due to Radiation Retinopathy

Jaeb Center for Health Research

NCT05844982

Recruiting 600 target

Safety and Durability of Sirolimus for Treatment of LAM

University of Cincinnati

NCT02432560

Recruiting 600 target

Vitaccess Real MG Registry

Vitaccess

NCT06064461

Recruiting NA 596 target

APPROVE Trial: Evaluating a Prescription Digital Therapeutic for Treatment of OAB in Women

Medstar Health Research Institute

NCT06797245

Recruiting Phase 1 590 target

A Study of GSK5764227 in Participants With. Advanced Solid Tumors (EMBOLD PanTumor-101)

GlaxoSmithKline

NCT06551142

Recruiting 580 target

PULSED AF Post-Approval Study

Medtronic Cardiac Ablation Solutions

NCT06578104

Recruiting NA 564 target

CGM for Management of Type 2 Diabetes in Pregnancy

University of Alabama at Birmingham

NCT06628453

Recruiting 560 target

Project Mountain - Comparing SpO2 and SaO2 for Accuracy

Philips Clinical & Medical Affairs Global

NCT06372106

Recruiting Phase 2 550 target

Phase 2 Study of Inhaled SNG001 in Mechanically Ventilated Patients With Respiratory Viral Infection

Synairgen Research

NCT06999603

Recruiting NA 544 target

A Clinical Trial of Adaptive Treatment for Early Smoking Cessation Relapse

Medical University of South Carolina

NCT06118502

Recruiting 540 target

Use of a Cloud-connected Remote Blood Pressure Monitoring Program During the Postpartum Period for Hypertensive Women

University of South Carolina

NCT06096701

Recruiting NA 532 target

Multi-Site Trial of Navigation vs Treatment as Usual to Improve Initiation of Timely Adjuvant Therapy

Medical University of South Carolina

NCT05793151

Recruiting Phase 3 528 target

A Study to Evaluate Efficacy and Safety of MELT-300 for Procedural Sedation in Subjects Undergoing Cataract Extraction With Lens Replacement (CELR)

Melt Pharmaceuticals

NCT06383273

Recruiting NA 510 target

Evaluation of an Online Prostate Cancer Screening Decision Aid

David Siegel

NCT06610474

Recruiting NA 500 target

Encore PFO Closure Device - The PerFOrm Trial

Encore Medical

NCT05537753

Recruiting 500 target

A Registry of Subjects With Primary Indeterminate Lesions or Choroidal Melanoma

Aura Biosciences

NCT03941379

Recruiting NA 500 target

Cord Clamping Among Neonates With Congenital Heart Disease

Carl Backes, MD

NCT06153459

Recruiting 500 target

The MIRROR Registry: Minimally Invasive IntRaceRebral HemORrhage Evacuation

Integra LifeSciences Corporation

NCT04494295

Recruiting Phase 3 500 target

A Long-term Study of the Medicine Called Abrocitinib in Children Aged 2 Years and Older With Moderate to Severe Eczema

Pfizer

NCT06807281

Recruiting NA 500 target

Improving the Collaborative Health of Minority COVID-19 Survivor and Carepartner Dyads

University of South Carolina

NCT05370014

Recruiting 500 target

American Hepato-Pancreato-Biliary Association (AHPBA) Pancreatic Irreversible Electroporation (IRE) Registry

University of Louisville

NCT02674100

Recruiting 500 target

VIA Disc NP Registry 3.0

VIVEX Biologics

NCT06345690

Recruiting 500 target

ViewFlex X ICE First-in-Human Study

Abbott Medical Devices

NCT06772493

Recruiting 500 target

Pounce™ Thrombectomy System Retrospective Registry

SurModics

NCT05868161

Recruiting Phase 2 500 target

A Study of TAK-861 for the Treatment of Selected Central Hypersomnia Conditions

Takeda

NCT05816382

Recruiting Phase 2 492 target

DB-1311 in Combination With BNT327 or DB-1305 in Advanced/Metastatic Solid Tumors

DualityBio

NCT06953089

Recruiting Phase 2 488 target

A Study to Investigate the Safety and Efficacy of MEDI0618 Compared to Placebo in Adult Participants With Episodic Migraine

AbbVie

NCT06602479

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Recruiting status is reported by each study's sponsor and mirrored from the public registry. Always confirm current eligibility and status on ClinicalTrials.gov before contacting a study.

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