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NCT07199569 · ClinicalTrials.gov registry record · Phase 2
Comparability Trial of the MVA-BN Vaccine Manufactured in Different Production Cells
A Phase 2 study of Monkeypox (Mpox), sponsored by Bavarian Nordic.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 744
- Enrollment target
- 10
- Study locations
NCT07199569 is a Phase 2 study of Monkeypox (Mpox) that is actively recruiting participants, run by Bavarian Nordic. The registered enrollment target is 744 participants. The trial reports 10 study locations across 8 states.
The verdict
NCT07199569, a Phase 2 study of Monkeypox (Mpox), is actively recruiting participants, sponsored by Bavarian Nordic.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 744 participants
- Enrollment target
- 10
- Study locations
Study Summary
andomized, double-blind, phase 2b trial to assess comparability in immunogenicity, safety, and reactogenicity of MVA-BN vaccine manufactured in primary chicken embryo fibroblast (CEF) cells and the CCX.E10 quail cell line in adults
Conditions Studied
Interventions
- BIOLOGICAL Jynneos
- BIOLOGICAL MVA-BN (Quail)
Study Locations (10)
North Carolina
- Accellacare of Cary - Cary Medical Group - Cary
- Accellacare Research of Salisbury - Salisbury
Texas
- Avacare - Austin
- Avacare - Fort Worth
Iowa
- Accellacare and McFarland Clinic - Ames
Kansas
- Johnson County ClinTrials, LLC - Lenexa
New York
- Rochester Clinical Research, Inc - Rochester
South Carolina
- Accellacare of Charleston - Mt. Pleasant
Tennessee
- Accellacare - Knoxville - Knoxville
Virginia
- Velocity Clinical Research - Suffolk
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 744 participants |
| Start Date | 2025-10-27 |
| Est. Completion | 2026-10-31 |
| Phase | Phase 2 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07199569
The ClinicalTrials.gov registry entry for NCT07199569 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 744 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Bavarian Nordic, which has 41 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Monkeypox (Mpox) appearing as the primary indexed condition, and to 2 interventions - of which Jynneos is the first listed.
NCT07199569 reports 10 study locations spanning 8 distinct geographic areas - top geographies include North Carolina, Texas, Iowa.
Frequently Asked Questions
What is clinical trial NCT07199569 about?
NCT07199569 is a clinical study titled "Comparability Trial of the MVA-BN Vaccine Manufactured in Different Production Cells". andomized, double-blind, phase 2b trial to assess comparability in immunogenicity, safety, and reactogenicity of MVA-BN vaccine manufactured in primary chicken embryo fibroblast (CEF) cells and the CCX.E10 quail cell line in adults
What is the current status of trial NCT07199569?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 744 participants. The study started on 2025-10-27. Estimated completion is 2026-10-31.
What conditions does trial NCT07199569 study?
This clinical trial studies the following conditions: Monkeypox (Mpox).
What interventions are being tested in trial NCT07199569?
The interventions under investigation include: Jynneos (BIOLOGICAL), MVA-BN (Quail) (BIOLOGICAL).
Who is sponsoring clinical trial NCT07199569?
This trial is sponsored by Bavarian Nordic, which has 41 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07199569 being conducted?
This trial has 10 study locations across Iowa, Kansas, New York, North Carolina, South Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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