Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT05366881 · ClinicalTrials.gov registry record

cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease

A clinical trial of Breast Cancer and Colorectal Cancer, sponsored by Adela.

Recruiting
Registry status
7,000
Enrollment target
17
Study locations

NCT05366881 is a study of Breast Cancer and Colorectal Cancer that is actively recruiting participants, run by Adela. The registered enrollment target is 7,000 participants, above the 2,798-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (150% higher). The trial reports 17 study locations across 11 states.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT05366881, a study of Breast Cancer and Colorectal Cancer, is actively recruiting participants, sponsored by Adela.

RECRUITING
Registry status
7,000 participants
Enrollment target
17
Study locations

Study Summary

This is an observational case-control study to train and validate a genome-wide methylome enrichment platform to detect multiple cancer types and to differentiate amongst cancer types. The cancers included in this study are brain, breast, bladder, cervical, colorectal, endometrial, esophageal, gastric, head and neck, hepatobiliary, leukemia, lung, lymphoma, multiple myeloma, ovarian, pancreatic, prostate, renal, sarcoma, and thyroid. These cancers were selected based on their prevalence and mortality to maximize impact on clinical care. Additionally, the ability of the whole-genome methylome enrichment platform to detect minimal residual disease after completion of cancer treatment and to detect relapse prior to clinical presentation will be evaluated in lung cancer. This cancer was selected based on the existing clinical landscape and treatment availability.

Study Locations (17)

Kentucky

  • Baptist Corbin - Corbin
  • Baptist Hardin - Elizabethtown
  • Baptist Lexington - Lexington
  • Baptist Paducah - Paducah

Minnesota

  • Allina Health Cancer Institute - Minneapolis
  • Mayo Clinic - Rochester

South Carolina

  • Medical University of South Carolina - Charleston
  • McLeod Health - Florence

Tennessee

  • Baptist (BHMCC) - Memphis
  • Vanderbilt-Ingram Cancer Center - Nashville

California

  • City of Hope - Duarte

Florida

  • Miami Cancer Institute - Miami

Georgia

  • North Georgia Health System - Gainesville

Indiana

  • Baptist Floyd - New Albany

Trial Details

FieldValue
Enrollment Target 7,000 participants
Start Date 2022-05-03
Est. Completion 2027-03

Sponsor

Adela

1 total trials

What the Registry Record Tells You About NCT05366881

The ClinicalTrials.gov registry entry for NCT05366881 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 7,000 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 2,798-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (150% higher). The listed sponsor is Adela, which has 1 total studies on file at ClinicalTrials.gov.

The record links to 10 conditions, with Breast Cancer appearing as the primary indexed condition, and to 0 interventions.

NCT05366881 reports 17 study locations spanning 11 distinct geographic areas - top geographies include Kentucky, Minnesota, South Carolina.

Frequently Asked Questions

What is clinical trial NCT05366881 about?

NCT05366881 is a clinical study titled "cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease". This is an observational case-control study to train and validate a genome-wide methylome enrichment platform to detect multiple cancer types and to differentiate amongst cancer types. The cancers included in this study are brain, breast, bladder, cervical, colorectal, endometrial, esophageal, gastr...

What is the current status of trial NCT05366881?

This trial is currently recruiting. The enrollment target is 7,000 participants. The study started on 2022-05-03. Estimated completion is 2027-03.

What conditions does trial NCT05366881 study?

This clinical trial studies the following conditions: Breast Cancer, Colorectal Cancer, Head and Neck Cancer, Endometrial Cancer, Bladder Cancer.

Who is sponsoring clinical trial NCT05366881?

This trial is sponsored by Adela, which has 1 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05366881 being conducted?

This trial has 17 study locations across California, Florida, Georgia, Indiana, Kentucky. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Breast Cancer

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.