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Find a clinical trial that's recruiting now
Search 24,857 actively recruiting US clinical trials by condition, drug, or state, each entry links straight to its NIH ClinicalTrials.gov record so you can check eligibility and contact the study team.
- 24,857
- trials recruiting now
- 14%
- of all US trials open to enrollment
- 52
- states with recruiting sites
A trial is listed as recruiting when its sponsor has marked it open to new participants on the public registry. Type a condition or drug name (for example, "breast cancer" or "pembrolizumab") to narrow the list, and add a state to find studies with a site near you. Results are ordered with the most relevant recruiting studies first; each card shows the study phase and enrollment target, and opens the full record, including eligibility criteria and contact details, on ClinicalTrials.gov.
Popular conditions
50 trials found
Parent and Family Obesity Intervention in Reducing Obesity Risk in Racial Ethnic Minority Families
M.D. Anderson Cancer Center
This clinical trial compares the effects of parent/caregiver-focused programs to family-focused programs in reducing obesity risk in racial ethnic minority families. Obesity tends to run in families, thus family...
NCT05094466
Individualized Lifestyle Intervention for Obesity Management Based on Obesity Phenotypes
Mayo Clinic
The purpose of this protocol is to define an "individualized diet" approach based on obesity related phenotypes (pathophysiology obesity classification), which would increase weight loss, adherence, and weight loss maintenance.
NCT04073394
Obesity and Pediatric Multiple Sclerosis
University of Virginia
...This study will evaluate the relationship between obesity, obesity-derived inflammatory mediators, and imaging metrics of MS severity in children. Understanding how childhood obesity contributes to MS severity/progression may yield fundamental...
NCT04593082
Underlying Mechanisms of Obesity-induced Obstructive Sleep Apnea
Brandon Nokes
...However, not all subjects with obesity develop obstructive sleep apnea. This study will attempt to determine the mechanistic drivers between obesity and obstructive sleep apnea.
NCT04793334
Re-energize With Nutrition, Exercise and Weight Loss
University of Pittsburgh
The purpose of this project is to establish a Center of Excellence in Research on Obesity that will focus on severe obesity. The prevalence of severe obesity (i.e., Class 2 and...
NCT00712127
Obesity Complicating Type 1 Diabetes: GLP-1 Analogue Anti-obesity Treatment
Yale University
More than 40% of young adults with type 1 diabetes (T1D) also have overweight or obesity. Each of these diagnoses increase the risk of adverse cardiovascular events. GLP-1 analogues are anti...
NCT06411210
Study of VI-0521 Compared to Placebo in Treatment of Diabetes and Obesity in Adults With Obesity-Related Co-Morbid Conditions
VIVUS
The purpose of this study is to evaluate the efficacy and safety of VI0521 compared to placebo in treatment of obesity in an adult population with obesity related co-morbid conditions.
NCT00553787
Early Childhood Obesity Programming by Intrauterine Growth Restriction
Montefiore Medical Center
The molecular mechanisms underlying developmental programming of childhood obesity remain poorly understood. Here, the investigators address major questions about early childhood obesity programming by studying CD3+ T-cells from intrauterine growth restricted...
NCT03402139
Obesity Surgery and Kidney Transplant for Patients With Obesity and Renal Failure
Vanderbilt University Medical Center
Gastric Bypass followed by renal transplantation is superior to medical management followed by renal transplant for patients with severe obesity and renal failure.
NCT02128802
Evaluating the Link Between Neighborhood Environments and Obesity Among African American Women
Boston University
African American women have higher rates of obesity than women of any other racial or ethnic group in the United States. Obesity can have many causes, including genetic and environmental factors. This...
NCT00356707
Vanderbilt Childhood Obesity Registry
Vanderbilt University Medical Center
In order to better understand early onset obesity and to identify patients in interested in future research studies, including clinical trials, we aim to develop a registry for patients with early onset...
NCT02957916
Healthy Futures Project: A Community Based Obesity Prevention Program
National Institute on Media and the Family
...Of greatest concern is the 300% increase in obesity rates among children and youth over the past twenty years. Childhood obesity is a precursor of adult obesity.
NCT00685555
Vitamin D Supplementation Reduces Renin-Angiotensin System Activity in Obesity
Brigham and Women's Hospital
Hypothesis: Vitamin D supplementation lower renin-angiotensin system activity in obesity. Specific Aim: To investigate whether Vitamin D supplementation in obesity improves the vascular sensitivity to angiotensin II.
NCT01068418
SMART Use of Medication for the Treatment of Adolescent Severe Obesity
University of Minnesota
This study will examine the timing and sequence of using adjunct obesity pharmacotherapy for adolescents with severe obesity who do not respond to lifestyle modification therapy alone.
NCT04007393
A Translational Understanding of Obesity-Related Phenotypes Using Brain Imaging and Manipulation
Drexel University
This study will examine a potential relationship between family history of obesity, that is whether people with at least one parent who had obesity in adulthood compared to people with two parents...
NCT06353464
Prevalence and Cardiovascular Effects of Growth Hormone Deficiency in Abdominal Obesity
Massachusetts General Hospital
...Obesity, and more specifically abdominal obesity, may cause decreased growth hormone (GH) levels. It is believed that GH deficiency may contribute to increased cardiovascular risk by affecting insulin resistance, inflammatory markers, and...
NCT00562796
Families on Track: A Digital Health Behavioral Intervention for Parents Seeking Treatment for Their Child With Obesity
Duke University
Current models of outpatient childhood obesity treatment focus on the child's health habits, with limited efficacy. In part, this may be because childhood obesity is highly sensitive to parental lifestyle habits...
NCT02767440
Communicating Risk Information for Obesity
Boston University
This study will examine the impact of providing genetic risk information for obesity on people's attitudes and beliefs about obesity, health behaviors and weight outcomes. Specifically, this study will examine the...
NCT01355224
Awareness, Care & Treatment in Obesity Management (ACTION) Study
Novo Nordisk A/S
The ACTION (Awareness, Care, and Treatment In Obesity management) study aims to identify perceptions, attitudes, behaviours, and potential barriers to effective obesity care across three respondent types: 1) People with Obesity, 2...
NCT03223493
Obesity and OSA in Pregnancy
University of Texas Southwestern Medical Center
The purposes of this project are 1) to compare the impact of maternal obesity versus excessive gestational weight gain on obstructive sleep apnea (OSA) in obese and non-obese women; 2) to...
NCT05654259
Characterization of Bile Acid Pathway in Obesity
Mayo Clinic
It is unknown whether the bile acid pathway is altered in obesity. This study is designed to compare obesity and health to determine if the bile acid pathway differs depending on health...
NCT03341052
Evaluation of a Family-based Pediatric Obesity Program: TEENS+
Virginia Commonwealth University
Investigators propose to pilot an adolescent obesity intervention, TEENS+, to examine the feasibility of this dietary intervention strategy and preliminary effectiveness of two models of parental involvement within adolescent obesity treatment.
NCT02262013
RESILIENCE: Personalizing Cardiovascular Health
Duke University
...However, some individuals with obesity appear to be resistant to CVD, and other individuals demonstrate resilience to obesity and CVD risk factors. The investigator's overall objective is to understand factors contributing...
NCT04551872
Weight Loss Clinical Decision Support
HealthPartners Institute
Despite steady increases in obesity prevalence, the more than 12 million obese U.S. adults with type 2 diabetes (T2DM) and severe obesity encounter a number of barriers to adopting effective surgical...
NCT05198765
Sarcopenic Obesity in the Elderly
University of Central Florida
...Increasingly, obesity has become a compounding factor in ageing-related sarcopenia. The coexistence of obesity and sarcopenia is termed sarcopenic obesity (SO). Older adults with SO are at higher risks of developing...
NCT06083909
Regulation of Muscle Protein Phenotype in Humans With Obesity
Mayo Clinic
A hallmark of muscle changes in obesity is an altered muscle fiber type profile, characterized by a reduced proportion of Type I fibers - a shift associated with adverse obesity-related health outcomes...
NCT04700800
Gut, Immune, and Vascular Health in Metabolically Healthy Obesity
Ball State University
The investigators seek to better understand how a single high-fat meal impacts gut, immune, and vascular outcomes in individuals with "metabolically healthy obesity" (obesity and largely normal cardiometabolic profile) and "metabolically...
NCT07559227
Genetic Disorders of Obesity Program Database
Baylor College of Medicine
This study collects data on children with severe, early-onset obesity.
NCT05747976
The Family Grocery Pilot: Optimal Defaults in Online Grocery Shopping Among Families
State University of New York at Buffalo
The obesity epidemic continues to be a major public health concern, impacting nearly one-fifth of US children. One of the most robust predictors of childhood obesity risk is parental obesity and...
NCT05899634
Study of Growth Hormone and Bone in Obesity
Massachusetts General Hospital
...With the growing prevalence of obesity in the U.S., understanding the pathophysiology of bone loss in this population is of importance to public health. Growth hormone (GH) is a critical mediator...
NCT01724489
New Mechanisms of Obesity
Yale University
Given the pervasiveness of Pediatric Obesity, it is imperative to understand its pathophysiology and develop alternative strategies to reverse this condition. Herein, investigators propose to elucidate the interaction between colonic fermentation and...
NCT06768827
Nutrition for Asthmatics with Obesity
Pennington Biomedical Research Center
This study will test the effect of diet on asthma in individuals with obesity.
NCT05222451
Obesity Assessment and Education Through the Internet
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
The purpose of this study is to develop a web-based obesity risk assessment and counseling tool and examine its feasibility and effectiveness in improving the rate and quality of physician counseling...
NCT00149682
Planned CORR: Planned Care for Obesity and Risk Reduction
University of California, San Diego
The researchers propose a randomized controlled trial to evaluate how well an intervention, Planned Care for Obesity \& Risk Reduction (Planned CORR), supports primary care treatment of obesity in adults with at least...
NCT01134029
Follow-up of Adolescent Bariatric Surgery
Children's Hospital Medical Center, Cincinnati
...The information may also be used to study causes of obesity, to determine the predictors of successful obesity treatment and for other obesity related research. Because of the importance of understanding the...
NCT00776776
Vascular Function, Endothelin, and Inflammation in Pre-diabetic Obesity Versus Lean Healthy Controls
Indiana University
...Does inflammation contribute importantly to concurrent defects in vascular and metabolic dysfunction in human pre-diabetic obesity? 2. Are there benefits of anti-inflammatory treatment strategies in pre-diabetic obesity in the...
NCT00837590
Childhood Obesity Prevention Program for Hispanics
Meharry Medical College
The purpose of this study is to evaluate the efficacy of a culturally-appropriate childhood obesity intervention with Hispanic families. The program aims at preventing childhood obesity by targeting parents to address...
NCT01156402
Study of a Smart Growth Community's Effect on Prevention of Obesity in Middle-, Moderately Low- and Low-Income Families
University of Southern California
...Overweight and obesity have been associated with multiple types of disease, including cancer. Living in a smart growth community may encourage behaviors that would reduce the risk of obesity. PURPOSE: This research...
NCT00986011
Estrogen Sensitivity and Ovulatory Dysfunction in Obesity
University of Colorado, Denver
...The disease state that is being evaluated is the obesity-related alterations in reproductive hormones * The obesity epidemic in the United States is advancing at an accelerated pace. It is estimated that...
NCT01381016
Family Functioning in Obesity Treatment for Mexican Americans
Becky Marquez
Mexican American families share similar elevated risks for obesity and obesity-related conditions, such as type 2 diabetes. Because negative family interactions and relationships (e.g., poor communication, high conflict, low emotional...
NCT05120804
Pediatric Obesity Weight Evaluation Registry (POWER) Study
Children's Hospital Medical Center, Cincinnati
The main objective of this study is to establish a national pediatric obesity registry known as POWER (Pediatric Obesity Weight Evaluation Registry). This registry will contain clinical data from individual comprehensive pediatric...
NCT02121132
Relation of Consummatory and Anticipatory Food Reward to Obesity
Oregon Research Institute
...Unfortunately, the treatment of choice for obesity (behavioral weight loss treatment) only results in a 10% reduction in body weight on average and most patients regain this weight within a few years...
NCT01807572
Effects of Change in Insulin Resistance and Systemic Inflammation on Brain Structure and Function
University of Minnesota
...The mechanisms underlying obesity related decline in cognitive function are not fully understood. The long-term goal of this project is to understand how obesity affects cognitive function, with the aim to...
NCT03215888
Evaluating Obesity-Mediated Mechanisms of Pancreatic Carcinogenesis in Minority Populations
H. Lee Moffitt Cancer Center and Research Institute
This study will evaluate obesity-mediated mechanisms of pancreatic carcinogenesis in minority populations.
NCT05687188
Functional MRI of Stress in Obesity
Yale University
To examine the influence of obesity on brain activation during food cue, stress, and neutral relaxing conditions
NCT01719484
Immunometabolism in Pediatric Obesity
Arkansas Children's Hospital Research Institute
This is a study to learn about obesity and how insulin resistance and Type 2 Diabetes develops in children.
NCT03960333
Safety and Efficacy of Xenical in Children and Adolescents With Obesity-Related Diseases
Jack Yanovski
...Individuals with the onset of obesity during childhood or adolescence are at an increased risk of obesity-related, diseases, both during adolescence and later in adult life. African American girls and women...
NCT00001723
A Pilot Study: High Versus Low Oxytocin Dosing for Induction of Labor in Pregnant Patients With Obesity
Ohio State University
Pregnant patients with obesity are more likely to undergo induction of labor and have a higher risk of failed induction compared to patients with normal weight. The association between maternal obesity and...
NCT05289869
Mechanisms Underlying Metabolic Syndrome in Obesity
Philip Kern
The purpose of this study is to better understand the link between obesity and diabetes or pre-diabetes.
NCT00579813
A Feasibility Study for the Treatment of Primary Obesity Cross-over Arm
USGI Medical
Cross-over arm of the pilot study evaluating a treatment for obesity.
NCT05939973
Read our methodology - how recruiting status is sourced and refreshed from the public registry.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Recruiting status is reported by each study's sponsor and mirrored from the public registry. Always confirm current eligibility and status on ClinicalTrials.gov before contacting a study.