Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

RECRUITING Phase 3

Depemokimab as an Extended treatmeNt Duration Biologic in Adults With Chronic Obstructive Pulmonary Disease (COPD) and Type 2 Inflammation (ENDURA -1)

NCT06959095 · View on ClinicalTrials.gov ↗

Study Summary

Depemokimab is being developed as a treatment for individuals with moderate to severe COPD. The aim of this study is to assess the efficacy and safety of depemokimab as an add-on medicine in participants with uncontrolled moderate to severe COPD with type 2 inflammation.

Interventions

  • DRUG Placebo
  • DRUG Depemokimab

Study Locations (15)

Other

  • GSK Investigational Site — Chengdu
  • GSK Investigational Site — Guangzhou
  • GSK Investigational Site — Hangzhou
  • GSK Investigational Site — Jiangmen
  • GSK Investigational Site — Jiangxi
  • GSK Investigational Site — Mianyang
  • GSK Investigational Site — Qingyuan
  • GSK Investigational Site — Zigong
  • GSK Investigational Site — Tokyo

Florida

  • GSK Investigational Site — Loxahatchee Groves
  • GSK Investigational Site — Miami

South Carolina

  • GSK Investigational Site — Rock Hill

Texas

  • GSK Investigational Site — Corsicana

Hunan

  • GSK Investigational Site — Changsha

Sichuan

  • GSK Investigational Site — Chengdu

Trial Details

FieldValue
Enrollment Target 981 participants
Start Date 2025-06-20
Est. Completion 2029-08-20
Phase Phase 3

Sponsor

GlaxoSmithKline

558 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT06959095

The ClinicalTrials.gov registry entry for NCT06959095 describes a study currently listed as recruiting. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 981 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is GlaxoSmithKline, which has 558 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Pulmonary Disease, Chronic Obstructive appearing as the primary indexed condition, and to 2 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT06959095 reports 15 study locations spanning 6 distinct geographic areas — top geographies include Other, Florida, South Carolina. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT06959095 about?

NCT06959095 is a clinical study titled "Depemokimab as an Extended treatmeNt Duration Biologic in Adults With Chronic Obstructive Pulmonary Disease (COPD) and Type 2 Inflammation (ENDURA -1)". Depemokimab is being developed as a treatment for individuals with moderate to severe COPD. The aim of this study is to assess the efficacy and safety of depemokimab as an add-on medicine in participants with uncontrolled moderate to severe COPD with type 2 inflammation.

What is the current status of trial NCT06959095?

This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 981 participants. The study started on 2025-06-20. Estimated completion is 2029-08-20.

What conditions does trial NCT06959095 study?

This clinical trial studies the following conditions: Pulmonary Disease, Chronic Obstructive. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT06959095?

The interventions under investigation include: Placebo (DRUG), Depemokimab (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT06959095?

This trial is sponsored by GlaxoSmithKline, which has 558 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT06959095 being conducted?

This trial has 15 study locations across Florida, South Carolina, Texas, Hunan, Sichuan. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial