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RECRUITING Phase 2

A Study to Evaluate the Immune Response and Safety of an Influenza Vaccine in Adults 18 Years of Age and Above

NCT07204964 · View on ClinicalTrials.gov ↗

Study Summary

The purpose of this study is to assess the reactogenicity, safety and immune response of GlaxoSmithKline's (GSK) messenger RNA (mRNA)-based multivalent seasonal influenza vaccine candidates administered in healthy younger and older adults.

Conditions Studied

Interventions

  • BIOLOGICAL Flu mRNA (Formulation B1)
  • BIOLOGICAL Flu mRNA (Formulation B3)
  • BIOLOGICAL Flu mRNA(Formulation A)
  • COMBINATION_PRODUCT Comparator 1
  • COMBINATION_PRODUCT Comparator 2

Study Locations (17)

Florida

  • GSK Investigational Site — Hialeah
  • GSK Investigational Site — Miami
  • GSK Investigational Site — Pembroke Pines

California

  • GSK Investigational Site — Canoga Park
  • GSK Investigational Site — Walnut Creek

Nevada

  • GSK Investigational Site — Carson City
  • GSK Investigational Site — Las Vegas

Texas

  • GSK Investigational Site — Austin
  • GSK Investigational Site — Garland

Other

  • GSK Investigational Site — Edegem
  • GSK Investigational Site — Ghent

Alabama

  • GSK Investigational Site — Guntersville

Georgia

  • GSK Investigational Site — Stockbridge

North Carolina

  • GSK Investigational Site — Greensboro

Trial Details

FieldValue
Enrollment Target 960 participants
Start Date 2025-10-07
Est. Completion 2026-09-17
Phase Phase 2

Sponsor

GlaxoSmithKline

558 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT07204964

The ClinicalTrials.gov registry entry for NCT07204964 describes a study currently listed as recruiting. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 960 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is GlaxoSmithKline, which has 558 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Influenza, Human appearing as the primary indexed condition, and to 5 interventions — of which Flu mRNA (Formulation B1) is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT07204964 reports 17 study locations spanning 11 distinct geographic areas — top geographies include Florida, California, Nevada. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT07204964 about?

NCT07204964 is a clinical study titled "A Study to Evaluate the Immune Response and Safety of an Influenza Vaccine in Adults 18 Years of Age and Above". The purpose of this study is to assess the reactogenicity, safety and immune response of GlaxoSmithKline's (GSK) messenger RNA (mRNA)-based multivalent seasonal influenza vaccine candidates administered in healthy younger and older adults.

What is the current status of trial NCT07204964?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 960 participants. The study started on 2025-10-07. Estimated completion is 2026-09-17.

What conditions does trial NCT07204964 study?

This clinical trial studies the following conditions: Influenza, Human. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT07204964?

The interventions under investigation include: Flu mRNA (Formulation B1) (BIOLOGICAL), Flu mRNA (Formulation B3) (BIOLOGICAL), Flu mRNA(Formulation A) (BIOLOGICAL), Comparator 1 (COMBINATION_PRODUCT), Comparator 2 (COMBINATION_PRODUCT). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT07204964?

This trial is sponsored by GlaxoSmithKline, which has 558 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT07204964 being conducted?

This trial has 17 study locations across Alabama, California, Florida, Georgia, Nevada. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial