Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

RECRUITING Phase 2

A Study to Assess the Efficacy and Safety of Verekitug in Participants With COPD

NCT06981078 · View on ClinicalTrials.gov ↗

Study Summary

The purpose of this study is to assess the efficacy and safety of verekitug (UPB-101) in participants with moderate-to-severe Chronic Obstructive Pulmonary Disease (COPD), an inflammatory lung disease.

Interventions

  • OTHER Placebo
  • DRUG Verekitug

Study Locations (20)

California

  • Kern Research Inc. — Bakersfield
  • PulmoCrit Associates — Encino
  • Torrance Clinical Research Institute — Lomita
  • Dream Team Clinical Research — Pomona
  • Apex Clinical Research — San Diego
  • Allianz Research Institute — Westminster

Florida

  • D&H Doral Research Center, LLC — Doral
  • Qway Research, LLC — Hialeah
  • Finlay Medical Research — Miami
  • Research Institute of South Florida — Miami
  • Florida Institute for Clinical Research,LLC — Orlando

Maryland

  • Velocity Clinical Research-Rockville — Rockville
  • Chesapeake Clinical Research, Inc — White Marsh

Colorado

  • Allianz Research Institute — Aurora

Georgia

  • Velocity Clinical Research-Savannah - Internal Medicine — Savannah

Illinois

  • Christie Clinic, LLC — Champaign

Iowa

  • The Iowa Clinic — West Des Moines

Minnesota

  • HealthPartners — Saint Paul

Trial Details

FieldValue
Enrollment Target 666 participants
Start Date 2025-07-02
Est. Completion 2028-07
Phase Phase 2

Sponsor

Upstream Bio

58 total trials

Interested in This Trial?

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT06981078

The ClinicalTrials.gov registry entry for NCT06981078 describes a study currently listed as recruiting. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 666 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Upstream Bio, which has 58 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Chronic Obstructive Pulmonary Disease appearing as the primary indexed condition, and to 2 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT06981078 reports 20 study locations spanning 10 distinct geographic areas — top geographies include California, Florida, Maryland. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT06981078 about?

NCT06981078 is a clinical study titled "A Study to Assess the Efficacy and Safety of Verekitug in Participants With COPD". The purpose of this study is to assess the efficacy and safety of verekitug (UPB-101) in participants with moderate-to-severe Chronic Obstructive Pulmonary Disease (COPD), an inflammatory lung disease.

What is the current status of trial NCT06981078?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 666 participants. The study started on 2025-07-02. Estimated completion is 2028-07.

What conditions does trial NCT06981078 study?

This clinical trial studies the following conditions: Chronic Obstructive Pulmonary Disease. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT06981078?

The interventions under investigation include: Placebo (OTHER), Verekitug (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT06981078?

This trial is sponsored by Upstream Bio, which has 58 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT06981078 being conducted?

This trial has 20 study locations across California, Colorado, Florida, Georgia, Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial