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NCT06999603 · ClinicalTrials.gov registry record · Phase 2
Phase 2 Study of Inhaled SNG001 in Mechanically Ventilated Patients With Respiratory Viral Infection
A Phase 2 study of Viral Pneumonia, sponsored by Synairgen Research.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 550
- Enrollment target
- 20
- Study locations
NCT06999603 is a Phase 2 study of Viral Pneumonia that is actively recruiting participants, run by Synairgen Research. The registered enrollment target is 550 participants. The trial reports 20 study locations across 14 states.
The verdict
NCT06999603, a Phase 2 study of Viral Pneumonia, is actively recruiting participants, sponsored by Synairgen Research.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 550 participants
- Enrollment target
- 20
- Study locations
Study Summary
The goal of this Phase 2 study is to assess about the safety, antiviral biomarker responses and efficacy of SNG001 when given to patients requiring invasive mechanical ventilation due to a respiratory virus infection. Its ability to speed up virus clearance and reduce mortality, compared with standard of care, will be studied. The study is split into two parts. All participants will receive standard of care in addition to SNG001 or placebo. In Part 1, the safety of SNG001 will be assessed. Participants of 50 years and older will receive study drug or placebo once a day for up to 14 days, whilst in hospital. In Part 2, the primary objective will be the efficacy of SNG001. Participants between 18 and 50 years with an immunocompromising condition and patients over 50 years (with or without an immunocompromising condition) will receive study drug once a day for up to 14 days, whilst in hospital.
Conditions Studied
Interventions
- DRUG Placebo
- DRUG SNG001
Study Locations (20)
Ohio
- University of Cincinnati Medical Center (UCMC) - Cincinnati
- The Cleveland Clinic Foundation - Cleveland
- The Ohio State University (OSU) - Columbus
- Mercy St. Vincent Medical Center - Toledo
California
- University of California - Davis - Sacramento
- Lundquist Institute for Biomedical Innovation at Harbor UCLA Medical Center - Torrance
Michigan
- Sinai-Grace Hospital - Detroit
- William Beaumont Hospital - Royal Oak
New York
- VA Western New York Healthcare system - Buffalo
- NYU Langone Tisch Hospital - New York
Florida
- NCH Pulmonary Critical Care - Naples
Georgia
- Emory University - Atlanta
Idaho
- Snake River Research, PLLC - Idaho Falls
Illinois
- Northwestern University - Chicago
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 550 participants |
| Start Date | 2025-09-02 |
| Est. Completion | 2027-05 |
| Phase | Phase 2 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06999603
The ClinicalTrials.gov registry entry for NCT06999603 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 550 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Synairgen Research, which has 3 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Viral Pneumonia appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT06999603 reports 20 study locations spanning 14 distinct geographic areas - top geographies include Ohio, California, Michigan.
Frequently Asked Questions
What is clinical trial NCT06999603 about?
NCT06999603 is a clinical study titled "Phase 2 Study of Inhaled SNG001 in Mechanically Ventilated Patients With Respiratory Viral Infection". The goal of this Phase 2 study is to assess about the safety, antiviral biomarker responses and efficacy of SNG001 when given to patients requiring invasive mechanical ventilation due to a respiratory virus infection. Its ability to speed up virus clearance and reduce mortality, compared with standa...
What is the current status of trial NCT06999603?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 550 participants. The study started on 2025-09-02. Estimated completion is 2027-05.
What conditions does trial NCT06999603 study?
This clinical trial studies the following conditions: Viral Pneumonia.
What interventions are being tested in trial NCT06999603?
The interventions under investigation include: Placebo (DRUG), SNG001 (DRUG).
Who is sponsoring clinical trial NCT06999603?
This trial is sponsored by Synairgen Research, which has 3 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06999603 being conducted?
This trial has 20 study locations across California, Florida, Georgia, Idaho, Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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