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Find a clinical trial that's recruiting now
Search 24,857 actively recruiting US clinical trials by condition, drug, or state, each entry links straight to its NIH ClinicalTrials.gov record so you can check eligibility and contact the study team.
- 24,857
- trials recruiting now
- 14%
- of all US trials open to enrollment
- 52
- states with recruiting sites
A trial is listed as recruiting when its sponsor has marked it open to new participants on the public registry. Type a condition or drug name (for example, "breast cancer" or "pembrolizumab") to narrow the list, and add a state to find studies with a site near you. Results are ordered with the most relevant recruiting studies first; each card shows the study phase and enrollment target, and opens the full record, including eligibility criteria and contact details, on ClinicalTrials.gov.
Popular conditions
50 trials found
E3 Hypertension - A Team-based, Multidisciplinary Model in Addressing Barriers to Hypertension Control
Rush University Medical Center
This study aims to compare a multidisciplinary clinical hypertension and social needs intervention to enhanced standard of care for hypertension management in primary care clinics with regards to hypertension control outcomes.
NCT06899750
Treatment of Pulmonary Arterial Hypertension Using the Aria CV Pulmonary Hypertension System
Aria CV
This prospective study is a multi-center early feasibility study assessing the safety and performance of the Aria CV Pulmonary Hypertension System in patients with pulmonary hypertension and right heart dysfunction.
NCT04555161
Staying Healthy After Childbirth: My Hypertension Education and Reaching Target Program for Postpartum
University of Wisconsin, Madison
A study of Staying Healthy After Childbirth (STAC) and My Hypertension Education And Reaching Target (MyHEART) for postpartum (p) patients to determine if health coaching can increase 12-month postpartum care attendance...
NCT05685251
Trans-pulmonary Biomarkers in Pulmonary Hypertension
Vanderbilt University
The investigators are testing whether the addition of Pulmonary Hypertension-related biomarkers, measured across the pulmonary circulation, to the standard hemodynamic evaluation for Pulmonary Hypertension will lead to more informed choices of...
NCT01961232
Veteran Preference For Group Visits and Its Effect on Hypertension Outcomes
US Department of Veterans Affairs
To determine racial/ethnic differences in preference for group visits in veterans with poorly controlled hypertension (State 2 hypertension) and determine the effect of group visits on health outcomes among veterans with...
NCT00439816
Inhaled Iloprost for Sarcoidosis-associated Pulmonary Hypertension
University of Cincinnati
This trial will study the treatment of sarcoidosis-associated pulmonary arterial hypertension with inhaled iloprost, a drug approved for primary pulmonary arterial hypertension.
NCT00403650
ADAPT-Altering Diet for African American Populations to Treat Hypertension
University of Alabama at Birmingham
...intervention and test the effectiveness of the intervention lower blood pressure in a group of African American participants at risk for developing hypertension (pre-hypertension) and those with mild hypertension (stage I).
NCT00621569
Treatment of Masked Hypertension
University of Minnesota
To date, most observational and all intervention studies have defined hypertension on the basis of clinic blood pressure (BP). Measurement of BP outside the clinic with home or ambulatory BP provides a...
NCT02142881
Group Visits to Improve Hypertension Management
US Department of Veterans Affairs
This study investigates group medical visits as a quality improvement strategy for hypertension. It studies group visits in which patients see their own primary care provider together with other patients who have...
NCT00129493
Improving Practice Patterns for the Treatment of Hypertension
US Department of Veterans Affairs
To improve the quality of hypertension care in our facility, while concurrently, examining the relative contribution of each aspect of a multi-factorial intervention designed to improve hypertension care.
NCT00265044
Treatment of Supine Hypertension in Autonomic Failure (CPAP)
Vanderbilt University Medical Center
Supine hypertension is a common problem that affects at least 50% of patients with primary autonomic failure. Supine hypertension can be severe and complicates the treatment of orthostatic hypotension. The purpose of...
NCT03312556
Hypertension and Sleep Disordered Breathing in Pediatrics
NYU Langone Health
The primary objective is to determine the prevalence of sleep disordered breathing in children with primary hypertension or pre hypertension. The secondary objectives are to determine any association factors for children with...
NCT00990899
Tadalafil for Sarcoidosis Associated Pulmonary Hypertension
University of North Carolina, Chapel Hill
This study is designed to assess safety and efficacy of tadalafil in patients with Sarcoidosis Associated Pulmonary Hypertension. Hypothesis: Tadalafil is safe and effective in treating pulmonary hypertension in patients with Sarcoidosis
NCT01324999
Early, Simple and Reliable Detection of Pulmonary Arterial Hypertension (PAH) in Systemic Sclerosis (SSc)
Actelion
A two-stage prospective observational cohort study in scleroderma patients to evaluate screening tests and the incidence of pulmonary arterial hypertension and pulmonary hypertension
NCT00706082
Multi-center, Web Based Observational Study of Pulmonary Hypertension in Scleroderma Patients
Georgetown University
The purpose of this study is to determine the timeline of progression from pre-pulmonary hypertension to diagnosable pulmonary hypertension based on right heart catheterization. Moreover, to determine the timeline for progression...
NCT00377949
Observational Study of Actigraphy in Pediatric Pulmonary Arterial Hypertension
University of Colorado, Denver
This study plans to learn more about activity levels in children with pulmonary hypertension. Pulmonary hypertension is a condition where the pressure in the lungs is higher than normal. This can affect...
NCT04745000
Epigenomic Dysregulation in Preeclampsia-Associated Chronic Hypertension
Ohio State University
...It is unknown whether aberrant DNA methylation in pregnancy-induced hypertension is the mechanism by which chronic hypertension develops in these women remote from pregnancy nor is it known if hypertension remote...
NCT01682304
Effects of Pulmonary Hypertension Therapy in Atypical Pulmonary Arterial Hypertension
Mayo Clinic
The purpose of this study is to characterize the clinical and hemodynamic response of Pulmonary Arterial Hypertension (PAH) therapy in patients with atypical PAH and risk factors for left heart disease.
NCT04787445
Investigating Behavior Change Methods for the Management of Hypertension
Texas A&M University
This project aims to promote general wellness using a mobile health intervention that incorporates health coaching to help manage hypertension. The mobile application (HyperCoach) does not intend to cure, mitigate, or prevent...
NCT07631546
Pediatric Hypertension Registry (PHREG)
Wake Forest University Health Sciences
Pediatric hypertension is increasingly common and is a precursor for adult cardiovascular and renal disease. But even during childhood, hypertension is associated with significant morbidity, including cognitive impairment and organ damage. However...
NCT03305562
A Pilot Study of Plasma Renin Activity Guided vs Generic Combination Therapy for Hypertension
University of North Carolina, Chapel Hill
The purpose of this study is to investigate the effect of plasma renin activity-guided therapy for determining hypertension treatment. Plasma renin is an enzyme in your blood that can be measured...
NCT01658657
Achieving Blood Pressure Control Together Study
Johns Hopkins University
African Americans represent a particularly vulnerable subgroup of persons with hypertension, as they are more likely than Whites to have hypertension, equally as likely to be aware of it and to be...
NCT01902719
Telemedicine Management of Hypertension
Wake Forest University Health Sciences
Explore barriers, facilitators, acceptability, feasibility, and fidelity of the telemedicine management of hypertension intervention
NCT05424744
A Study in Participants With Sarcoidosis-associated Pulmonary Hypertension (SAPH) to Assess the Efficacy and Safety of Oral Selexipag
Actelion
Oral selexipag is commercially available in several countries for the treatment of a particular group of pulmonary hypertension (PH) called pulmonary arterial hypertension (PAH). The aim of the present study is to...
NCT03942211
Spinal Cord Stimulation to Treat Hypertension
University of Minnesota
To investigate the exercise blood pressure response during a lower-extremity dynamic exercise in postmenopausal women with hypertension and to determine if lumbar epidural spinal cord stimulation reduces blood pressure during exercise...
NCT02828436
A Study to Evaluate CIN-107 for the Treatment of Patients With Uncontrolled Hypertension and Chronic Kidney Disease
AstraZeneca
This study will evaluate the efficacy and safety of CIN-107 for the treatment of hypertension in patients with uncontrolled hypertension (uHTN) and Chronic Kidney Disease (CKD).
NCT05432167
Pediatric Pulmonary Hypertension Network (PPHNet) Informatics Registry
New York Medical College
Patients are being asked to be in this research study because medical researchers hope that by gathering information about a large number of children with pulmonary hypertension over time, their understanding of...
NCT02249923
Groceries for Black Residents of Boston to Stop Hypertension Among Adults With Treated Hypertension
Beth Israel Deaconess Medical Center
GoFreshRx is a randomized trial, testing the effects of a home-delivered DASH-patterned grocery intervention on blood pressure in Black adults actively treated for hypertension, residing in Boston area urban food...
NCT05393232
Aspirin to Prevent Preeclampsia in Women With Elevated Blood Pressure and Stage 1 Hypertension (ASPPIRE)
Yale University
To determine if low dose aspirin reduces the incidence of hypertensive disorders of pregnancy (gestational hypertension, preeclampsia, eclampsia, and HELLP syndrome) in pregnant women with stage 1 hypertension and elevated blood pressure.
NCT04402385
Using Lay Health Advisors to Improve Hypertension Management
MetroHealth Medical Center
...The investigators propose to determine the impact of using trained lay health advisors to help patients address social contextual factors that influence the management of hypertension.
NCT03515005
A Master Protocol Study of Orforglipron (LY3502970) in Participants With Hypertension and Obesity or Overweight (ATTAIN-Hypertension) GZL1
Eli Lilly and Company
GZL1 is an independent study conducted under the GZPL master protocol. GZL1 will evaluate the efficacy and safety of orforglipron for treatment of hypertension in participants with obesity or overweight.
NCT06948435
Obstructive Sleep Apnea (OSA) in Pulmonary Arterial Hypertension (PAH)
Inova Health Care Services
The purpose of this study is to determine whether pulmonary arterial hypertension can worsen or even cause sleep apnea. It is hypothesized that if pulmonary arterial hypertension does indeed worsen or cause...
NCT01835080
Pulmonary Hypertension Biorepository and Registry
University of Kansas Medical Center
Establish a pulmonary hypertension registry and biorepository to lead towards a further understanding of the disease.
NCT04808596
Mechanisms of Hypertension in Women With Polycystic Ovary Syndrome
Yale University
Women with androgen excess polycystic ovary syndrome (AE-PCOS) leads to hypertension.
NCT04327934
Postpartum Management of Hypertension in Pregnancy With Hydrochlorothiazide
The University of Texas Medical Branch, Galveston
Postpartum prophylactic HCTZ administration for prevention and relapse of preeclampsia or gestational hypertension.
NCT03298802
A Master Protocol Study of Orforglipron (LY3502970) in Participants With Hypertension and Obesity or Overweight (ATTAIN-Hypertension) GZL2
Eli Lilly and Company
GZL2 is an independent study conducted under the GZPL master protocol. GZL2 study will evaluate the efficacy and safety of orforglipron for treatment of hypertension in participants with obesity or overweight.
NCT06952530
Acute Control of Chronic Hypertension
Albany Medical College
The purpose of this study is to understand if administration of a personalized dose of the anti-hypertensive medication, labetalol, based on patient's history of preexisting hypertension, will be more effective...
NCT03877692
Improving Hypertension Control
Medical College of Wisconsin
* The overall hypothesis for the project is that racial health disparities will be reduced by improving hypertension control in African Americans. * This will be accomplished through the development, implementation, and evaluation of...
NCT01910857
Ambrisentan (Letairis) for Sarcoidosis Associated Pulmonary Hypertension
Medical University of South Carolina
Hypothesis: Ambrisentan (Letairis ®) is safe and effective in treating pulmonary hypertension in patients with Sarcoidosis
NCT00851929
Whole Exome Sequencing in Finding Causative Variants in Germline DNA Samples From Patients With Hypertension Receiving Bevacizumab for Breast Cancer
National Cancer Institute (NCI)
This research trial studies whole exome sequencing in finding causative variants in germline deoxyribonucleic acid (DNA) samples from patients with hypertension receiving bevacizumab for breast cancer. Studying samples of germline DNA in...
NCT02610413
A Study to Investigate the Efficacy and Safety of Baxdrostat in Participants With Uncontrolled Hypertension on Two or More Medications Including Participants With Resistant Hypertension
AstraZeneca
...720 participants aged ≥ 18 years with hypertension, despite a stable regimen of 2 antihypertensive agents at baseline, one of which is a diuretic (uncontrolled hypertension); or ≥ 3 antihypertensive agents at baseline, one...
NCT06034743
A COmmunity and Tech-Based ApproaCh for Hypertension Self-MANagement
Case Western Reserve University
The prevalence of hypertension among U.S. adults increased from 32% to 46% and African Americans are disproportionately impacted. Self-managing hypertension presents challenges such as dealing with complex treatment regimen, including...
NCT03724487
Targeting Endoplasmic Reticulum Stress in Human Hypertension
University of North Texas Health Science Center
There is strong evidence suggesting that endoplasmic reticulum stress contributes to neurogenic and vascular hypertension in various animal models, however this has never been explored in humans. Therefore, this project will fill...
NCT06025630
Guidelines for Drug Therapy of Hypertension: Multi-Site Implementation
US Department of Veterans Affairs
Clinical trial of implementation of clinical practice guidelines for managing hypertension in primary care clinics.
NCT00122161
The Hypotensive Effects of Home-Based Isometric Handgrip Training in Older Adults With Pre-Hypertension and Hypertension - The HoldAge Trial
University Institute of Maia
New data suggests that isometric handgrip training (IHT) might become a novel tool in the treatment of hypertension. The main purpose of this research project is to evaluate the effects of home...
NCT04275037
Hypertension in Management of Military Medicine
United States Naval Medical Center, San Diego
This study is a retrospective database review of primary care appointments of patients' charts with new diagnoses of hypertension.
NCT00134849
Community Health Workers Using Patient Stories to Support Hypertension Management
University of Massachusetts, Worcester
Community Health Workers (CHWs) using patient stories to support hypertension management is a randomized controlled trial to evaluate the implementation of a CHW-delivered culturally appropriate storytelling intervention for english and spanish...
NCT02874547
Epidemiology and Pathogenesis of HIV-Associated Pulmonary Hypertension
University of California, San Francisco
The purpose of this study is to describe the epidemiology of pulmonary hypertension in individuals with HIV infection and to investigate its pathogenesis. We propose to conduct a prospective observational cohort study...
NCT00845013
A Study of the Effectiveness and Safety of Ramipril in the Treatment of Hypertension in Children and Adolescents
Pfizer
The primary purpose of this study is to evaluate the blood pressure lowering effects of ramipril, an FDA-approved drug for the treatment of hypertension in adults, in children and adolescents aged...
NCT00389519
PORtopulmonary Hypertension Treatment wIth maCitentan - a randOmized Clinical Trial
Actelion
24-week study to evaluate the efficacy and safety of macitentan for the treatment of portopulmonary hypertension.
NCT02382016
Read our methodology - how recruiting status is sourced and refreshed from the public registry.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Recruiting status is reported by each study's sponsor and mirrored from the public registry. Always confirm current eligibility and status on ClinicalTrials.gov before contacting a study.