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NCT03848312 · ClinicalTrials.gov registry record · Phase 3
Preventing Alzheimer's With Cognitive Training
A Phase 3 study of Age-related Cognitive Decline and Alzheimer's Disease and Related Dementias, sponsored by University of South Florida.
- Recruiting
- Registry status
- Phase 3
- Development phase
- 7,600
- Enrollment target
- 7
- Study locations
NCT03848312 is a Phase 3 study of Age-related Cognitive Decline and Alzheimer's Disease and Related Dementias that is actively recruiting participants, run by University of South Florida. The registered enrollment target is 7,600 participants, above the 373-participant average among 10 other Age-related Cognitive Decline trials with a reported enrollment target (1938% higher). The trial reports 7 study locations across 3 states.
The verdict
NCT03848312, a Phase 3 study of Age-related Cognitive Decline and Alzheimer's Disease and Related Dementias, is actively recruiting participants, sponsored by University of South Florida.
- RECRUITING
- Registry status
- Phase 3
- Development phase
- 7,600 participants
- Enrollment target
- 7
- Study locations
Study Summary
Dementia is the most expensive medical condition in the US and increases in prevalence with age. More than 5 million Americans have Alzheimer's disease, the most common form of dementia. Mild cognitive impairment is a transitional stage between normal cognitive aging and Alzheimer's disease or another type of dementia, and is indicative of higher risk for dementia. In addition to the obvious health and quality-of-life ramifications of dementia, there are high direct (e.g., subsidizing residential care needs) and indirect (e.g., lost productivity of family caregivers) economic costs. Implementing interventions to prevent MCI and dementia among older adults is of critical importance to health and maintained quality-of-life for millions of Americans. Recent data analyses from the Advanced Cognitive Training in Vital Elderly study (ACTIVE) indicate that a specific cognitive intervention, speed of processing training (SPT), significantly delays the incidence of cognitive impairment across 10 years. The primary contribution of the proposed research will be the determination of whether this cognitive training technique successfully delays the onset of clinically defined MCI or dementia across three years.
Conditions Studied
Interventions
- BEHAVIORAL Cognitive Training
- BEHAVIORAL Computerized Cognitive Stimulation
Study Locations (7)
Florida
- University of Florida - Gainesville
- University of Florida - Jacksonville
- University of North Florida - Jacksonville
- The Roskamp Institute - Sarasota
- University of South Florida - Tampa
North Carolina
- Duke Health - Durham
South Carolina
- Clemson University Institute for Engaged Aging - Seneca
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 7,600 participants |
| Start Date | 2019-02-19 |
| Est. Completion | 2026-01-31 |
| Phase | Phase 3 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT03848312
The ClinicalTrials.gov registry entry for NCT03848312 describes a study currently listed as recruiting, categorized as Phase 3. The registered enrollment target is 7,600 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 373-participant average among 10 other Age-related Cognitive Decline trials with a reported enrollment target (1938% higher). The listed sponsor is University of South Florida, which has 252 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Age-related Cognitive Decline appearing as the primary indexed condition, and to 2 interventions - of which Cognitive Training is the first listed.
NCT03848312 reports 7 study locations spanning 3 distinct geographic areas - top geographies include Florida, North Carolina, South Carolina.
Frequently Asked Questions
What is clinical trial NCT03848312 about?
NCT03848312 is a clinical study titled "Preventing Alzheimer's With Cognitive Training". Dementia is the most expensive medical condition in the US and increases in prevalence with age. More than 5 million Americans have Alzheimer's disease, the most common form of dementia. Mild cognitive impairment is a transitional stage between normal cognitive aging and Alzheimer's disease or anoth...
What is the current status of trial NCT03848312?
This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 7,600 participants. The study started on 2019-02-19. Estimated completion is 2026-01-31.
What conditions does trial NCT03848312 study?
This clinical trial studies the following conditions: Age-related Cognitive Decline, Alzheimer's Disease and Related Dementias.
What interventions are being tested in trial NCT03848312?
The interventions under investigation include: Cognitive Training (BEHAVIORAL), Computerized Cognitive Stimulation (BEHAVIORAL).
Who is sponsoring clinical trial NCT03848312?
This trial is sponsored by University of South Florida, which has 252 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03848312 being conducted?
This trial has 7 study locations across Florida, North Carolina, South Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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