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Weight Loss clinical trials
31 of 119 indexed Weight Loss trials are currently recruiting.
119 US clinical trials · 31 currently recruiting
Weight Loss is the subject of 119 registered US clinical trials on ClinicalTrials.gov, 31 of them currently open to new participants. 5 are in Phase 3-4 (later-stage) and 15 in Phase 1-2 (earlier-stage). The most active sponsor is Drexel University, running 4 of these trials.
The research picture
Weight Loss has 119 registered US clinical trials, 31 of them open to new participants right now, about 26% of the total.
- 31
- recruiting participants now
- 26%
- of trials open to enrollment
- 5
- in Phase 3–4 (later-stage)
- 4
- top sponsor: Drexel University
Active & Recent Trials
119 total, page 3 of 3
Impact of Exogenous Ketones on Indices of Keto-Adaptation in Obese Subjects on Weight Reducing Diets.
Ohio State University
NCT06449287
Topiramate in Adolescents With Severe Obesity
University of Minnesota
NCT01859013
Bariatric Scalable Internet Treatments
Yale University
NCT03680703
Evaluation of Safety, Efficacy and Thermogenesis-induction of RZL-012 in Overweight and Obese Volunteers
Raziel Therapeutics
NCT03171415
Sleep During Weight Loss and Weight Loss Maintenance
Dartmouth-Hitchcock Medical Center
NCT03774563
Ignite Pilot: Goal Setting in a Digital Weight Loss Intervention
Stanford University
NCT05715242
Time Restricted Feeding for Weight Loss and Cardio-protection
University of Illinois at Chicago
NCT02948517
Individualized Diet Improvement Program for Weight Loss and Maintenance, Cohort 2
University of Illinois at Urbana-Champaign
NCT04605640
Mobile Behavior Change Program for Weight Loss in Breast Cancer Survivors
Noom
NCT04753268
Role Of Metabolic Adaptation In Weight Regain
Pennington Biomedical Research Center
NCT05766358
TOPS for African American Breast Cancer Survivors
Duke University
NCT04741802
Qsymia as an Adjunct to Surgical Therapy in the Superobese
Wake Forest University Health Sciences
NCT02301416
Impact of Metabolic Surgery on Pancreatic, Renal and Cardiovascular Health in Youth With Type 2 Diabetes
University of Colorado, Denver
NCT03620773
A Study of a Values-Based Intervention to Promote Weight Loss
Drexel University
NCT03991676
A Virtual-reality Based Approach to Improve Behavioral Weight Management Outcomes
California Polytechnic State University-San Luis Obispo
NCT04534088
The Effects of Alcohol Consumption on Central Adiposity
Pennington Biomedical Research Center
NCT03521817
PACE-CALL: A Weight Control Intervention for Survivors of Childhood Leukemia
University of California, San Diego
NCT01171599
Timing of Meals for Weight Loss
The University of Tennessee, Knoxville
NCT02204735
Dietary Pork, Appetite and Weight Loss in Human
Purdue University
NCT01006343
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 3 |
| Phase 2 | 12 |
| Phase 3 | 2 |
| Phase 4 | 3 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Weight Loss Trial Landscape
119 indexed Weight Loss studies · 31 recruiting (26%).
Phase mix: 5 late (III/IV) vs 15 early (I/II).
Top sponsor: Drexel University (4 trials), 9 others listed. 19 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Weight Loss?
PlainTrial tracks 119 US clinical trials for Weight Loss, of which 31 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Weight Loss?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.