Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Weight Loss: early-phase trial registry
31 of 119 indexed Weight Loss trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #105 of 28,707 conditions by registered trial count.
119 US clinical trials · 31 currently recruiting · #105 of 28,707 conditions by registered trial count
Weight Loss: 119 US clinical trials tracked, 31 recruiting.
Weight Loss is the subject of 119 registered US clinical trials on ClinicalTrials.gov, 31 of them currently open to new participants. 5 are in Phase 3-4 (later-stage) and 15 in Phase 1-2 (earlier-stage). The most active sponsor is Drexel University, running 4 of these trials.
Enrollment posture brief
Registry condition weight-loss
OPEN 31 | RECR 26% | LATE 5 | EARLY 15 | RANK #105 | SPON 4
Volume-matched condition peers
Nearest open-share peer: Barrett's Esophagus (26% recruiting · 23 trials)
Weight Loss lists 31 open slots (26% of 119 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Weight Loss on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Weight Loss is recruiting below its size-band peers.
31 of 119 indexed trials (26.1%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Weight Loss trials is spread across many organizations.
Drexel University accounts for 4 of 119 trials (3.4%). 85 distinct sponsors appear on at least one study for this condition label.
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Typical Weight Loss enrolment sits around 79 participants.
Median target enrolment is 79 among the 117 trials that report a genuine target (sentinel values excluded). 66 of those (56.4%) plan for fewer than 100 participants.
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Weight Loss research is mostly interventional.
107 interventional and 12 observational studies make up this index (89.9% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
119 total, page 3 of 3
Impact of Exogenous Ketones on Indices of Keto-Adaptation in Obese Subjects on Weight Reducing Diets.
Ohio State University
NCT06449287
Topiramate in Adolescents With Severe Obesity
University of Minnesota
NCT01859013
Bariatric Scalable Internet Treatments
Yale University
NCT03680703
Evaluation of Safety, Efficacy and Thermogenesis-induction of RZL-012 in Overweight and Obese Volunteers
Raziel Therapeutics
NCT03171415
Sleep During Weight Loss and Weight Loss Maintenance
Dartmouth-Hitchcock Medical Center
NCT03774563
Ignite Pilot: Goal Setting in a Digital Weight Loss Intervention
Stanford University
NCT05715242
Time Restricted Feeding for Weight Loss and Cardio-protection
University of Illinois at Chicago
NCT02948517
Individualized Diet Improvement Program for Weight Loss and Maintenance, Cohort 2
University of Illinois at Urbana-Champaign
NCT04605640
Mobile Behavior Change Program for Weight Loss in Breast Cancer Survivors
Noom
NCT04753268
Role Of Metabolic Adaptation In Weight Regain
Pennington Biomedical Research Center
NCT05766358
TOPS for African American Breast Cancer Survivors
Duke University
NCT04741802
Qsymia as an Adjunct to Surgical Therapy in the Superobese
Wake Forest University Health Sciences
NCT02301416
Impact of Metabolic Surgery on Pancreatic, Renal and Cardiovascular Health in Youth With Type 2 Diabetes
University of Colorado, Denver
NCT03620773
A Study of a Values-Based Intervention to Promote Weight Loss
Drexel University
NCT03991676
A Virtual-reality Based Approach to Improve Behavioral Weight Management Outcomes
California Polytechnic State University-San Luis Obispo
NCT04534088
The Effects of Alcohol Consumption on Central Adiposity
Pennington Biomedical Research Center
NCT03521817
PACE-CALL: A Weight Control Intervention for Survivors of Childhood Leukemia
University of California, San Diego
NCT01171599
Timing of Meals for Weight Loss
The University of Tennessee, Knoxville
NCT02204735
Dietary Pork, Appetite and Weight Loss in Human
Purdue University
NCT01006343
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 3 |
| Phase 2 | 12 |
| Phase 3 | 2 |
| Phase 4 | 3 |
Top Sponsors
Named interventions
Most-linked intervention names on Weight Loss records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Weight Loss trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Weight Loss page
119 registered trials, 31 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 31 Weight Loss trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Drexel University sponsors the most Weight Loss trials on record, review their full trial history before evaluating a specific study. See Drexel University's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Weight Loss condition card totals 119 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.