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ClinicalTrials.gov 31 recruiting now official registry

Weight Loss clinical trials

31 of 119 indexed Weight Loss trials are currently recruiting.

119 US clinical trials · 31 currently recruiting

Weight Loss is the subject of 119 registered US clinical trials on ClinicalTrials.gov, 31 of them currently open to new participants. 5 are in Phase 3-4 (later-stage) and 15 in Phase 1-2 (earlier-stage). The most active sponsor is Drexel University, running 4 of these trials.

The research picture

Weight Loss has 119 registered US clinical trials, 31 of them open to new participants right now, about 26% of the total.

31
recruiting participants now
26%
of trials open to enrollment
5
in Phase 3–4 (later-stage)
4
top sponsor: Drexel University
Phase 13Phase 212Phase 32Phase 43

Active & Recent Trials

119 total, page 3 of 3

COMPLETED NA 37 participants

Impact of Exogenous Ketones on Indices of Keto-Adaptation in Obese Subjects on Weight Reducing Diets.

Ohio State University

NCT06449287

COMPLETED Phase 2 34 participants

Topiramate in Adolescents With Severe Obesity

University of Minnesota

NCT01859013

COMPLETED NA 33 participants

Bariatric Scalable Internet Treatments

Yale University

NCT03680703

COMPLETED Phase 2 32 participants

Evaluation of Safety, Efficacy and Thermogenesis-induction of RZL-012 in Overweight and Obese Volunteers

Raziel Therapeutics

NCT03171415

COMPLETED 32 participants

Sleep During Weight Loss and Weight Loss Maintenance

Dartmouth-Hitchcock Medical Center

NCT03774563

COMPLETED NA 32 participants

Ignite Pilot: Goal Setting in a Digital Weight Loss Intervention

Stanford University

NCT05715242

COMPLETED NA 31 participants

Time Restricted Feeding for Weight Loss and Cardio-protection

University of Illinois at Chicago

NCT02948517

COMPLETED NA 30 participants

Individualized Diet Improvement Program for Weight Loss and Maintenance, Cohort 2

University of Illinois at Urbana-Champaign

NCT04605640

COMPLETED NA 30 participants

Mobile Behavior Change Program for Weight Loss in Breast Cancer Survivors

Noom

NCT04753268

COMPLETED 27 participants

Role Of Metabolic Adaptation In Weight Regain

Pennington Biomedical Research Center

NCT05766358

COMPLETED NA 26 participants

TOPS for African American Breast Cancer Survivors

Duke University

NCT04741802

COMPLETED Phase 2 25 participants

Qsymia as an Adjunct to Surgical Therapy in the Superobese

Wake Forest University Health Sciences

NCT02301416

COMPLETED Phase 1 24 participants

Impact of Metabolic Surgery on Pancreatic, Renal and Cardiovascular Health in Youth With Type 2 Diabetes

University of Colorado, Denver

NCT03620773

COMPLETED NA 19 participants

A Study of a Values-Based Intervention to Promote Weight Loss

Drexel University

NCT03991676

COMPLETED NA 15 participants

A Virtual-reality Based Approach to Improve Behavioral Weight Management Outcomes

California Polytechnic State University-San Luis Obispo

NCT04534088

COMPLETED NA 12 participants

The Effects of Alcohol Consumption on Central Adiposity

Pennington Biomedical Research Center

NCT03521817

COMPLETED NA 12 participants

PACE-CALL: A Weight Control Intervention for Survivors of Childhood Leukemia

University of California, San Diego

NCT01171599

COMPLETED NA 8 participants

Timing of Meals for Weight Loss

The University of Tennessee, Knoxville

NCT02204735

COMPLETED NA

Dietary Pork, Appetite and Weight Loss in Human

Purdue University

NCT01006343

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Phase Distribution

PhaseTrial count
Phase 1 3
Phase 2 12
Phase 3 2
Phase 4 3

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Weight Loss Trial Landscape

119 indexed Weight Loss studies · 31 recruiting (26%).

Phase mix: 5 late (III/IV) vs 15 early (I/II).

Top sponsor: Drexel University (4 trials), 9 others listed. 19 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Weight Loss?

PlainTrial tracks 119 US clinical trials for Weight Loss, of which 31 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Weight Loss?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.