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NCT06449287 · ClinicalTrials.gov registry record · NA

Impact of Exogenous Ketones on Indices of Keto-Adaptation in Obese Subjects on Weight Reducing Diets.

A NA study of Weight Loss and Ketogenic Diet, sponsored by Ohio State University.

Completed
Registry status
NA
Development phase
37
Enrollment target
1
Study location

NCT06449287 is a NA study of Weight Loss and Ketogenic Diet that has completed, run by Ohio State University. The registered enrollment target is 37 participants, below the 1,501-participant average among 116 other Weight Loss trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT06449287, a NA study of Weight Loss and Ketogenic Diet, has completed, sponsored by Ohio State University.

COMPLETED
Registry status
NA
Development phase
37 participants
Enrollment target
1
Study location

Study Summary

This project will be a three-group controlled 6-wk feeding study where all meals are prepared and provided to obese participants. All participants will be fed a 25% energy-restricted diet. Two diets will be very low in carbohydrate (i.e., ketogenic diets) designed to induce nutritional ketosis and fat loss. Another diet will be low in fat and saturated fat but contain the same total calories. Participants will be randomly assigned to a Ketone Supplement group who are provided an exogenous pre-formed source of beta-hydroxybutyrate (BOHB) or a Control group that only receives the standard ketogenic diet. Randomization will be stratified based on insulin resistance, sex, and body composition to ensure balanced group assignment. Because of timing of recruitment (i.e., after most of the ketogenic groups have already completed the study), the low-fat group will not be randomized. Outcome measurements will be made at various intervals over the 6-wk intervention.

Conditions Studied

Weight Loss Ketogenic Diet

Interventions

  • BIOLOGICAL Blood Draw
  • OTHER Diet
  • BIOLOGICAL Ketone/Glucose Monitoring
  • OTHER Body Composition
  • BIOLOGICAL Urine Analysis

Study Locations (1)

Ohio

  • The Ohio State University - Columbus

Trial Details

FieldValue
Enrollment Target 37 participants
Start Date 2018-07-05
Est. Completion 2019-08-21
Phase NA

Sponsor

Ohio State University

552 total trials

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What the Registry Record Tells You About NCT06449287

The ClinicalTrials.gov registry entry for NCT06449287 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 37 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 1,501-participant average among 116 other Weight Loss trials with a reported enrollment target (98% lower). The listed sponsor is Ohio State University, which has 552 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Weight Loss appearing as the primary indexed condition, and to 5 interventions - of which Blood Draw is the first listed.

NCT06449287 reports 1 study location spanning 1 distinct geographic area - top geographies include Ohio.

Frequently Asked Questions

What is clinical trial NCT06449287 about?

NCT06449287 is a clinical study titled "Impact of Exogenous Ketones on Indices of Keto-Adaptation in Obese Subjects on Weight Reducing Diets.". This project will be a three-group controlled 6-wk feeding study where all meals are prepared and provided to obese participants. All participants will be fed a 25% energy-restricted diet. Two diets will be very low in carbohydrate (i.e., ketogenic diets) designed to induce nutritional ketosis and f...

What is the current status of trial NCT06449287?

This trial is currently completed. It is a NA study. The enrollment target is 37 participants. The study started on 2018-07-05. Estimated completion is 2019-08-21.

What conditions does trial NCT06449287 study?

This clinical trial studies the following conditions: Weight Loss, Ketogenic Diet.

What interventions are being tested in trial NCT06449287?

The interventions under investigation include: Blood Draw (BIOLOGICAL), Diet (OTHER), Ketone/Glucose Monitoring (BIOLOGICAL), Body Composition (OTHER), Urine Analysis (BIOLOGICAL).

Who is sponsoring clinical trial NCT06449287?

This trial is sponsored by Ohio State University, which has 552 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06449287 being conducted?

This trial has 1 study location across Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.