Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Weight Loss: early-phase trial registry
31 of 119 indexed Weight Loss trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #105 of 28,707 conditions by registered trial count.
119 US clinical trials · 31 currently recruiting · #105 of 28,707 conditions by registered trial count
Weight Loss: 119 US clinical trials tracked, 31 recruiting.
Weight Loss is the subject of 119 registered US clinical trials on ClinicalTrials.gov, 31 of them currently open to new participants. 5 are in Phase 3-4 (later-stage) and 15 in Phase 1-2 (earlier-stage). The most active sponsor is Drexel University, running 4 of these trials.
Enrollment posture brief
Registry condition weight-loss
OPEN 31 | RECR 26% | LATE 5 | EARLY 15 | RANK #105 | SPON 4
Volume-matched condition peers
Nearest open-share peer: Barrett's Esophagus (26% recruiting · 23 trials)
Weight Loss lists 31 open slots (26% of 119 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Weight Loss on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Weight Loss is recruiting below its size-band peers.
31 of 119 indexed trials (26.1%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Weight Loss trials is spread across many organizations.
Drexel University accounts for 4 of 119 trials (3.4%). 85 distinct sponsors appear on at least one study for this condition label.
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Typical Weight Loss enrolment sits around 79 participants.
Median target enrolment is 79 among the 117 trials that report a genuine target (sentinel values excluded). 66 of those (56.4%) plan for fewer than 100 participants.
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Weight Loss research is mostly interventional.
107 interventional and 12 observational studies make up this index (89.9% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
119 total, page 2 of 3
Lorcaserin in Obesity: Identification of CNS Targets Using FMRI
Beth Israel Deaconess Medical Center
NCT02400359
Evaluation of the Effects of a Biostimulator and Dermal Fillers for Cheek Augmentation and Contour Deficiencies
Galderma R&D
NCT06351358
Healthy Eating Patterns During a Lifestyle Intervention
The University of Tennessee, Knoxville
NCT01682317
Hepatic Energy Fluxes in NASH and NAS Patients
University of Minnesota
NCT03997422
WeighT LOSS Surgery and Comprehensive Cardiometabolic Responses to to EXercise
Massachusetts General Hospital
NCT06576050
Evaluation of Bariatric Endoscopic Antral Myotomy (BEAM) as a Treatment for Obesity
Brigham and Women's Hospital
NCT05713071
Weight Management Demonstration Project: HEALTH
RTI International
NCT01307280
Integrated Community-Clinical Linkage Model to Promote Weight Loss Among South Asians With Pre-Diabetes
NYU Langone Health
NCT03188094
Health Outcomes After Participating in Exercise (HOPE)
Wake Forest University Health Sciences
NCT03430115
Gestational Weight Gain and Postpartum Weight Loss in Active Duty Women (Moms Fit 2 Fight)
University of Tennessee
NCT03057808
Study of an International Commercial Program on Weight Loss and Health Outcomes
University of North Carolina, Chapel Hill
NCT03571893
Delicious Eating for Life in Southern Homes
University of North Carolina, Chapel Hill
NCT04302727
Rural Disparities in Pediatric Obesity: The iAmHealthy Intervention
University of Kansas Medical Center
NCT03304249
Effect of Exercise on Prevention of Weight Gain
University of Pittsburgh
NCT00177502
Behavioral Activation for Smoking Cessation and the Prevention of Post-Cessation Weight Gain
Abramson Cancer Center at Penn Medicine
NCT02906787
A Randomized Trial of Recommendations for Exercise to Prevent Weight Regain
University of Kansas
NCT01664715
VK2735 for Weight Management Phase 2 (Venture Oral Dosing)
Viking Therapeutics
NCT06828055
Project Activate: Mindfulness and Acceptance Based Behavioral Treatment for Weight Loss
Drexel University
NCT04337619
Weight Management in Rural Communities
University of Kansas
NCT02932748
Spark: Finding the Optimal Tracking Strategy for Weight Loss in a Digital Health Intervention
Stanford University
NCT05249465
A Mentor-Based Approach to Long-Term Weight Loss
University of Pittsburgh
NCT00177697
Lorcaserin: Real World Experience in an Insurance-Based Weight Management Clinic
Scripps Whittier Diabetes Institute
NCT03552107
Single Arm Trial of a Multi-component Commercial Digital Weight Loss Program
University of Connecticut
NCT04302389
Facebook and Friends: Developing an Effective Online Social Network for Weight Loss
University of Connecticut
NCT02656680
University Of Pennsylvania Weight Loss Study
University of Pennsylvania
NCT01167634
A Study to Evaluate the Effect of SlimBiotics Probiotic Formula on Weight Management and Metabolic Health Outcomes
Slimbiotics
NCT05917314
Bitter Taste and Weight Loss in Women
Rutgers University
NCT01856660
Partners at Meals - Respite Care and Home (PAM)
Medical University of South Carolina
NCT03622814
Healthy Body Healthy Souls in the Marshallese Population
University of Arkansas
NCT03377244
The Collateral Impact of Bariatric Surgery on Families
Geisinger Clinic
NCT02021630
The Role of High Intensity Interval Training in the Treatment of Adolescent Obesity
Virginia Commonwealth University
NCT03361644
Impact of Volunteer Peer-Led Intervention for Weight Control in Primary Care
Milton S. Hershey Medical Center
NCT01850550
Evaluation of Ovarian Morphology and Function in Overweight Women During Weight Loss
Cornell University
NCT01785719
Phone Coaching for Weight Loss Maintenance
The Miriam Hospital
NCT04293055
A Comparative Effectiveness Study Evaluating the Effects of Thermogenic Supplements on Body Composition
Integrative Health Technologies
NCT01423019
Effect of Soy Protein and Colorado Diet on Weight Loss and Maintenance
DuPont Nutrition and Health
NCT02380963
Healthy4Baby: Preventing Postpartum Weight Retention Among Low-Income, Black Women
Temple University
NCT01530776
Helping Employees Lose Pounds
University of Michigan
NCT02853877
The Effect of Weight Loss and Dietary Protein Intake on Bone
Rutgers University
NCT00473031
OA Clinic-Community CARE Model
University of North Carolina, Chapel Hill
NCT05349500
Effects of Lactobacillus Plantarum KABP-51 Probiotic on Body Composition, Microbiome and Mood in Healthy Overweight Adults
3 Waves Wellness
NCT06808061
Effects of Human Milk Oligosaccharide Ingestion on Weight Loss and Markers of Health
Advanced Protein Technologies Corporation
NCT06547801
Active Nutrition Program on Weight Loss
University of Memphis
NCT06249698
Esophageal Cytology With FISH in Detecting Esophageal Cancer
OHSU Knight Cancer Institute
NCT02100189
Eating Mindfully to Prevent Weight Regain
University of Utah
NCT04847843
ObeSity and Jobs in SoCioeconomically Disadvantaged CommUnities: A Randomized CLinical Precision Public HealTh Intervention --The SCULPT-Job Study
University of California, San Francisco
NCT04709549
Intermittent Fasting, Caloric Restriction and Body Composition in Obese Men and Women
Skidmore College
NCT02525419
Effects of Dietary Protein on Musculoskeletal Health During Calorie Deficiency
United States Army Research Institute of Environmental Medicine
NCT01292395
Examining the Effect of Ondansetron on Bowel Prep Success
State University of New York - Downstate Medical Center
NCT05439772
Sleep Goal-focused Online Access to Lifestyle Support
University of Pittsburgh
NCT05942326
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 3 |
| Phase 2 | 12 |
| Phase 3 | 2 |
| Phase 4 | 3 |
Top Sponsors
Named interventions
Most-linked intervention names on Weight Loss records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Weight Loss trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Weight Loss page
119 registered trials, 31 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 31 Weight Loss trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Drexel University sponsors the most Weight Loss trials on record, review their full trial history before evaluating a specific study. See Drexel University's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Weight Loss condition card totals 119 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.