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Irinotecan in Treating Aging Patients With Solid Tumors
NCT00026195 · View on ClinicalTrials.gov ↗
Study Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Aging may affect the way these drugs work. PURPOSE: Phase I trial to determine the relationship between aging and the effectiveness of irinotecan in treating patients who have solid tumors.
Conditions Studied
Interventions
- DRUG irinotecan hydrochloride
Study Locations (20)
California
- Rebecca and John Moores UCSD Cancer Center — La Jolla
- Cedars-Sinai Medical Center — Los Angeles
- Veterans Affairs Medical Center - San Francisco — San Francisco
- UCSF Comprehensive Cancer Center — San Francisco
Illinois
- MBCCOP - University of Illinois at Chicago — Chicago
- Veterans Affairs Medical Center - Chicago (Westside Hospital) — Chicago
- University of Chicago Cancer Research Center — Chicago
District of Columbia
- Lombardi Cancer Center — Washington D.C.
- Walter Reed Army Medical Center — Washington D.C.
Massachusetts
- Dana-Farber Cancer Institute — Boston
- University of Massachusetts Memorial Medical Center - University Campus — Worcester
Minnesota
- Veterans Affairs Medical Center - Minneapolis — Minneapolis
- University of Minnesota Cancer Center — Minneapolis
Missouri
- Veterans Affairs Medical Center - Columbia (Truman Memorial) — Columbia
- Ellis Fischel Cancer Center - Columbia — Columbia
Delaware
- CCOP - Christiana Care Health Services — Wilmington
Florida
- CCOP - Mount Sinai Medical Center — Miami Beach
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 140 participants |
| Start Date | 2001-09 |
| Est. Completion | 2006-06 |
| Phase | Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00026195
The ClinicalTrials.gov registry entry for NCT00026195 describes a study currently listed as completed. It is categorized as Phase 1, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 140 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Alliance for Clinical Trials in Oncology, which has 147 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Unspecified Adult Solid Tumor, Protocol Specific appearing as the primary indexed condition, and to 1 intervention — of which irinotecan hydrochloride is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT00026195 reports 20 study locations spanning 11 distinct geographic areas — top geographies include California, Illinois, District of Columbia. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT00026195 about?
NCT00026195 is a clinical study titled "Irinotecan in Treating Aging Patients With Solid Tumors". RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Aging may affect the way these drugs work. PURPOSE: Phase I trial to determine the relationship between aging and the effectiveness of irinotecan in treating patients who have sol...
What is the current status of trial NCT00026195?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 140 participants. The study started on 2001-09. Estimated completion is 2006-06.
What conditions does trial NCT00026195 study?
This clinical trial studies the following conditions: Unspecified Adult Solid Tumor, Protocol Specific. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT00026195?
The interventions under investigation include: irinotecan hydrochloride (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT00026195?
This trial is sponsored by Alliance for Clinical Trials in Oncology, which has 147 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT00026195 being conducted?
This trial has 20 study locations across California, Delaware, District of Columbia, Florida, Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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