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NCT05899439 · ClinicalTrials.gov registry record

Immune Function and the Progression to T1D

A clinical trial of Type 1 Diabetes, sponsored by University of Florida.

Recruiting
Registry status
2,800
Enrollment target
3
Study locations

NCT05899439 is a study of Type 1 Diabetes that is actively recruiting participants, run by University of Florida. The registered enrollment target is 2,800 participants, above the 809-participant average among 178 other Type 1 Diabetes trials with a reported enrollment target (246% higher). The trial reports 3 study locations across 3 states.

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The verdict

NCT05899439, a study of Type 1 Diabetes, is actively recruiting participants, sponsored by University of Florida.

RECRUITING
Registry status
2,800 participants
Enrollment target
3
Study locations

Study Summary

To elucidate the mechanisms by which type 1 diabetes-associated genes; IFIH1, TYK2, IKZF4, as well as total genetic risk, impart functional immunoregulatory abnormalities that result in expansion of self-reactive adaptive immune cells, defective regulatory/effector mechanisms in T cells, inflammatory antigen presenting cells, and abnormal immune function in T cells and B cells.

Conditions Studied

Type 1 Diabetes

Interventions

  • OTHER blood draw

Study Locations (3)

Florida

  • Kieran McGrail - Gainesville

Ohio

  • The Ohio State University - Columbus

Texas

  • Baylor College of Medicine, Center for Research Advancement - Texas Children's Hospital - Houston

Trial Details

FieldValue
Enrollment Target 2,800 participants
Start Date 2005-01-01
Est. Completion 2085-01-01

Sponsor

University of Florida

1,106 total trials

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What the Registry Record Tells You About NCT05899439

The ClinicalTrials.gov registry entry for NCT05899439 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 2,800 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 809-participant average among 178 other Type 1 Diabetes trials with a reported enrollment target (246% higher). The listed sponsor is University of Florida, which has 1,106 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Type 1 Diabetes appearing as the primary indexed condition, and to 1 intervention - of which blood draw is the first listed.

NCT05899439 reports 3 study locations spanning 3 distinct geographic areas - top geographies include Florida, Ohio, Texas.

Frequently Asked Questions

What is clinical trial NCT05899439 about?

NCT05899439 is a clinical study titled "Immune Function and the Progression to T1D". To elucidate the mechanisms by which type 1 diabetes-associated genes; IFIH1, TYK2, IKZF4, as well as total genetic risk, impart functional immunoregulatory abnormalities that result in expansion of self-reactive adaptive immune cells, defective regulatory/effector mechanisms in T cells, inflammator...

What is the current status of trial NCT05899439?

This trial is currently recruiting. The enrollment target is 2,800 participants. The study started on 2005-01-01. Estimated completion is 2085-01-01.

What conditions does trial NCT05899439 study?

This clinical trial studies the following conditions: Type 1 Diabetes.

What interventions are being tested in trial NCT05899439?

The interventions under investigation include: blood draw (OTHER).

Who is sponsoring clinical trial NCT05899439?

This trial is sponsored by University of Florida, which has 1,106 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05899439 being conducted?

This trial has 3 study locations across Florida, Ohio, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.