Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT05901675 · ClinicalTrials.gov registry record · NA

EMPOWER: Effects of Weight Loss and Exercise Post-stroke

A NA study of Obesity and Stroke, sponsored by Medical University of South Carolina.

Recruiting
Registry status
NA
Development phase
130
Enrollment target
1
Study location

NCT05901675: Recruiting NA study of Obesity and Stroke, sponsored by Medical University of South Carolina.

NCT05901675 is a NA study of Obesity and Stroke that is actively recruiting participants, run by Medical University of South Carolina. The registered enrollment target is 130 participants, below the 819-participant average among 1,053 other Obesity trials with a reported enrollment target (84% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT05901675, a NA study of Obesity and Stroke, is actively recruiting participants, sponsored by Medical University of South Carolina.

RECRUITING
Registry status
NA
Development phase
130 participants
Enrollment target
1
Study location

Study Summary

The prevalence of obesity among U.S. adults is \~40% and is projected to climb. It is well documented that obesity is associated with increased levels of disability as well as risk for numerous adverse health-related outcomes; including occurrence of stroke and all-cause mortality. Obesity is highly prevalent in stroke survivors (\~30-45% of stroke survivors have BMI\>30) and is associated with reductions in physical function and increased disability. Furthermore, neurological sequelae following stroke result in a myriad of residual impairments that contribute to significant reductions in physical activity, which further increase the risk for obesity. The alarmingly high (and increasing) rates of obesity amongst stroke survivors represents an area of critical clinical need and, despite an abundance of information regarding weight loss approaches in neurologically healthy individuals, there is a lack of information regarding the impact of intentional weight loss on overweight and obese survivors of stroke. Thus, the purpose of this study it investigate the effect of varying weight loss approaches on physical function and psychosocial outcomes in chronic stroke survivors.

Primary Outcome

Participating in a lifestyle management program (DIET or DIET+Ex) will improve performance on the six-minute walk test (6MWT) compared to those in the waitlist control and DIET groups.

Conditions Studied

Interventions

  • OTHER Lifestyle Management Program
  • OTHER Post-stroke Optimization of Walking using Explosive Resistance

Study Locations (1)

South Carolina

  • College of Health Professions - Charleston

Trial Details

FieldValue
Enrollment Target 130 participants
Start Date 2023-07-07
Est. Completion 2028-03
Phase NA

What NCT05901675 shows while recruiting

NCT05901675 is an interventional study that assigns participants to a tested intervention. The registered 130 participants enrollment target is mid-sized for trials with a published cap, below the 819-participant average among 1,053 other Obesity trials with a reported enrollment target (84% lower).

The record links to 2 conditions, with Obesity appearing as the primary indexed condition, and to 2 interventions - of which Lifestyle Management Program is the first listed.

NCT05901675 reports a single indexed study location in South Carolina.

Frequently Asked Questions

What is clinical trial NCT05901675 about?

NCT05901675 is a clinical study titled "EMPOWER: Effects of Weight Loss and Exercise Post-stroke". The prevalence of obesity among U.S. adults is \~40% and is projected to climb. It is well documented that obesity is associated with increased levels of disability as well as risk for numerous adverse health-related outcomes; including occurrence of stroke and all-cause mortality. Obesity is highly...

What is the current status of trial NCT05901675?

This trial is currently recruiting. It is a NA study. The enrollment target is 130 participants. The study started on 2023-07-07. Estimated completion is 2028-03.

What conditions does trial NCT05901675 study?

This clinical trial studies the following conditions: Obesity, Stroke.

What interventions are being tested in trial NCT05901675?

The interventions under investigation include: Lifestyle Management Program (OTHER), Post-stroke Optimization of Walking using Explosive Resistance (OTHER).

Who is sponsoring clinical trial NCT05901675?

This trial is sponsored by Medical University of South Carolina, which has 755 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05901675 being conducted?

This trial has 1 study location across South Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Obesity

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT05901675's enrollment target sits among peer trials

130 418th of 1053 higher than 633 of 1,053 other Obesity trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Obesity trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT01492036 · 130 participants

    Long-Term Follow-Up of Recipient of Gene Transfer Research

  • NCT01631617 · 130 participants · Phase 2

    Effects of Treatments on Atopic Dermatitis

  • NCT02368041 · 130 participants

    Utility of Thenar Near Infrared Spectroscopy (NIRS) in Pediatric Patients With Heart Failure

  • NCT02604277 · 130 participants · NA

    Suicidal Behavior in Patients Diagnosed With Bipolar Disorder

Similar registry start date

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

  • NCT07125183 · started 2026-12 · Phase 2

    Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma

  • NCT07292298 · started 2026-11 · Phase 2

    Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

  • NCT04263285 · started 2026-10 · NA

    Treatment of Depression Post-SCI

Source: ClinicalTrials.gov NCT05901675, the US trial registry maintained by the National Library of Medicine. NCT05901675 (mid enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.