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NCT05701280 · ClinicalTrials.gov registry record · NA

Pilot/Pivotal Study of DBS+Rehab After Stroke

A NA study of Stroke and Upper Extremity Paresis, sponsored by Enspire DBS Therapy.

Recruiting
Registry status
NA
Development phase
202
Enrollment target
10
Study locations

NCT05701280: Recruiting NA study of Stroke and Upper Extremity Paresis, sponsored by Enspire DBS Therapy.

NCT05701280 is a NA study of Stroke and Upper Extremity Paresis that is actively recruiting participants, run by Enspire DBS Therapy. The registered enrollment target is 202 participants, below the 12,016-participant average among 454 other Stroke trials with a reported enrollment target (98% lower). The trial reports 10 study locations across 10 states. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT05701280, a NA study of Stroke and Upper Extremity Paresis, is actively recruiting participants, sponsored by Enspire DBS Therapy.

RECRUITING
Registry status
NA
Development phase
202 participants
Enrollment target
10
Study locations

Study Summary

The RESTORE Stroke Study will evaluate the safety and effectiveness of DBS+Rehab for treating arm weakness and reduced function after a stroke.

Primary Outcome

The change in FMA-UE is significantly greater for subjects who receive Test treatment (Tt) than Control treatment (Ct).

Conditions Studied

Stroke Upper Extremity Paresis

Interventions

  • DEVICE Deep Brain Stimulation
  • OTHER Rehabilitation

Study Locations (10)

Arizona

  • Barrow Neurological Institute (BNI) - Phoenix

Florida

  • Mayo Clinic Florida - Jacksonville

Maryland

  • Johns Hopkins School of Medicine - Baltimore

Massachusetts

  • Massachusetts General Hospital - Boston

Minnesota

  • Mayo Clinic - Rochester

New York

  • NYU Langone Health - New York

Ohio

  • Cleveland Clinic - Cleveland

Pennsylvania

  • Thomas Jefferson University - Philadelphia

Trial Details

FieldValue
Enrollment Target 202 participants
Start Date 2023-02-03
Est. Completion 2030-06
Phase NA
Enspire DBS Therapy

2 total trials

What NCT05701280 shows while recruiting

NCT05701280 is an interventional study that assigns participants to a tested intervention. The registered 202 participants enrollment target is mid-sized for trials with a published cap, below the 12,016-participant average among 454 other Stroke trials with a reported enrollment target (98% lower).

The record links to 2 conditions, with Stroke appearing as the primary indexed condition, and to 2 interventions - of which Deep Brain Stimulation is the first listed.

NCT05701280 lists 10 locations in 10 states (Arizona, Florida, Maryland).

Frequently Asked Questions

What is clinical trial NCT05701280 about?

NCT05701280 is a clinical study titled "Pilot/Pivotal Study of DBS+Rehab After Stroke". The RESTORE Stroke Study will evaluate the safety and effectiveness of DBS+Rehab for treating arm weakness and reduced function after a stroke.

What is the current status of trial NCT05701280?

This trial is currently recruiting. It is a NA study. The enrollment target is 202 participants. The study started on 2023-02-03. Estimated completion is 2030-06.

What conditions does trial NCT05701280 study?

This clinical trial studies the following conditions: Stroke, Upper Extremity Paresis.

What interventions are being tested in trial NCT05701280?

The interventions under investigation include: Deep Brain Stimulation (DEVICE), Rehabilitation (OTHER).

Who is sponsoring clinical trial NCT05701280?

This trial is sponsored by Enspire DBS Therapy, which has 2 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05701280 being conducted?

This trial has 10 study locations across Arizona, Florida, Maryland, Massachusetts, Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Learn More About Clinical Trials

Similar trials for Stroke

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT05701280's enrollment target sits among peer trials

202 94th of 454 higher than 360 of 454 other Stroke trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Stroke trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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More recruiting context for NCT05701280

Source: ClinicalTrials.gov NCT05701280, the US trial registry maintained by the National Library of Medicine. NCT05701280 (mid enrollment · multi site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.