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NCT05907629 · ClinicalTrials.gov registry record
Comparison of Anti-coagulation and Anti-Platelet Therapies for Intracranial Vascular Atherostenosis- Magnetic Resonance Imaging
A clinical trial of Stroke and Intracranial Atherosclerotic Stenosis (ICAS), sponsored by Yale University.
- Recruiting
- Registry status
- 300
- Enrollment target
- 13
- Study locations
NCT05907629: Recruiting study of Stroke and Intracranial Atherosclerotic Stenosis (ICAS), sponsored by Yale University.
NCT05907629 is a study of Stroke and Intracranial Atherosclerotic Stenosis (ICAS) that is actively recruiting participants, run by Yale University. The registered enrollment target is 300 participants, below the 12,016-participant average among 454 other Stroke trials with a reported enrollment target (98% lower). The trial reports 13 study locations across 9 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05907629, a study of Stroke and Intracranial Atherosclerotic Stenosis (ICAS), is actively recruiting participants, sponsored by Yale University.
- RECRUITING
- Registry status
- 300 participants
- Enrollment target
- 13
- Study locations
Study Summary
CAPTIVA-MRI is an observational multimodal MR imaging study that is ancillary to the CAPTIVA trial \[a 3-arm, double-blind Phase III trial conducted at approximately 115 StrokeNet sites randomizing patients with stroke attributed to 70-99% intracranial atherosclerotic stenosis (ICAS) to aspirin plus ticagrelor, clopidogrel, or rivaroxaban.\] The primary goal of this ancillary study is to determine if MRI biomarkers can potentially identify ICAS patients who fail best medical management. The CAPTIVA-MRI study leverages the CAPTIVA trial design and implementation to capture information that will inform and facilitate the next generation of ICAS trials and the management of patients with ICAS.
Primary Outcome
Recurrent ischemic stroke, defined as symptomatic infarct in the vascular territory of the index stroke artery. This outcome is centrally adjudicated in CAPTIVA using an American Heart Association definition of ischemic stroke
Conditions Studied
Interventions
- OTHER MRI
Study Locations (13)
Illinois
- SIH Memorial Hospital of Carbondale - Carbondale
- University of Illinois Hospital - Chicago
- University of Chicago Medical Center - Chicago
Florida
- Baptist Medical Center Jacksonville - Jacksonville
- Jackson Memorial Hospital, Miami - Miami
New York
- Buffalo General Medical Center - Buffalo
- North Shore University Hospita - Manhasset
Alabama
- University of Alabama Hospital - Birmingham
Connecticut
- Yale New Haven Hospital - New Haven
District of Columbia
- MedStar Washington Hospital Center - Washington D.C.
Missouri
- Barnes Jewish Hospital - St Louis
North Carolina
- Carolinas Medical Center - Charlotte
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 300 participants |
| Start Date | 2024-06-24 |
| Est. Completion | 2029-03-31 |
What NCT05907629 shows while recruiting
NCT05907629 is an observational study that tracks outcomes without assigning an intervention. The registered 300 participants enrollment target is mid-sized for trials with a published cap, below the 12,016-participant average among 454 other Stroke trials with a reported enrollment target (98% lower).
The record links to 2 conditions, with Stroke appearing as the primary indexed condition, and to 1 intervention - of which MRI is the first listed.
NCT05907629 lists 13 locations in 9 states (Illinois, Florida, New York).
Frequently Asked Questions
What is clinical trial NCT05907629 about?
NCT05907629 is a clinical study titled "Comparison of Anti-coagulation and Anti-Platelet Therapies for Intracranial Vascular Atherostenosis- Magnetic Resonance Imaging". CAPTIVA-MRI is an observational multimodal MR imaging study that is ancillary to the CAPTIVA trial \[a 3-arm, double-blind Phase III trial conducted at approximately 115 StrokeNet sites randomizing patients with stroke attributed to 70-99% intracranial atherosclerotic stenosis (ICAS) to aspirin plus...
What is the current status of trial NCT05907629?
This trial is currently recruiting. The enrollment target is 300 participants. The study started on 2024-06-24. Estimated completion is 2029-03-31.
What conditions does trial NCT05907629 study?
This clinical trial studies the following conditions: Stroke, Intracranial Atherosclerotic Stenosis (ICAS).
What interventions are being tested in trial NCT05907629?
The interventions under investigation include: MRI (OTHER).
Who is sponsoring clinical trial NCT05907629?
This trial is sponsored by Yale University, which has 1,492 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05907629 being conducted?
This trial has 13 study locations across Alabama, Connecticut, District of Columbia, Florida, Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT05907629's enrollment target sits among peer trials
300 75th of 454 higher than 377 of 454 other Stroke trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Stroke trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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