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NCT06116630 · ClinicalTrials.gov registry record

StrokeCog-BBB to Study Cognitive Outcomes Following Stroke

A clinical trial of Stroke, sponsored by Stanford University.

Recruiting
Registry status
350
Enrollment target
1
Study location

NCT06116630: Recruiting study of Stroke, sponsored by Stanford University.

NCT06116630 is a study of Stroke that is actively recruiting participants, run by Stanford University. The registered enrollment target is 350 participants, below the 12,016-participant average among 454 other Stroke trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT06116630, a study of Stroke, is actively recruiting participants, sponsored by Stanford University.

RECRUITING
Registry status
350 participants
Enrollment target
1
Study location

Study Summary

The goal of this observational study is to learn about cognitive outcomes in stroke patients. The main question it aims to answer are: 1. Is blood-brain barrier permeability compromised for years after stroke, 2. Is a blood biomarker of imbalanced angiogenesis dysregulated in chronic stroke and 3. Are there biomarkers that separately or together predicts cognitive decline after stroke, and are other MRI, blood, and clinical characteristics that are associated. Participants will undergo cognitive testing and MRIs two years apart. Researchers will compare cognitive outcomes in non-stroke patients who have cardiovascular risk factors to understand the effects of stroke on these outcomes.

Primary Outcome

Patients will undergo MRI imaging and cognitive testing. Amount of leakage in the blood vessels with be quantified. Scores on the cognitive tests will be normalized with Z scores. The amount of leakage and the z scores will be correlated to better understand the relationship between blood brain barrier leakage and cognition.

Conditions Studied

Stroke

Interventions

  • DIAGNOSTIC_TEST DCE-MRI

Study Locations (1)

California

  • Stanford University Hospital - Palo Alto

Trial Details

FieldValue
Enrollment Target 350 participants
Start Date 2022-05-17
Est. Completion 2027-12-31
Stanford University

1,744 total trials

What NCT06116630 shows while recruiting

NCT06116630 is an observational study that tracks outcomes without assigning an intervention. The registered 350 participants enrollment target is mid-sized for trials with a published cap, below the 12,016-participant average among 454 other Stroke trials with a reported enrollment target (97% lower).

The record links to 1 condition, with Stroke appearing as the primary indexed condition, and to 1 intervention - of which DCE-MRI is the first listed.

NCT06116630 reports a single indexed study location in California.

Frequently Asked Questions

What is clinical trial NCT06116630 about?

NCT06116630 is a clinical study titled "StrokeCog-BBB to Study Cognitive Outcomes Following Stroke". The goal of this observational study is to learn about cognitive outcomes in stroke patients. The main question it aims to answer are: 1. Is blood-brain barrier permeability compromised for years after stroke, 2. Is a blood biomarker of imbalanced angiogenesis dysregulated in chronic stroke and 3. A...

What is the current status of trial NCT06116630?

This trial is currently recruiting. The enrollment target is 350 participants. The study started on 2022-05-17. Estimated completion is 2027-12-31.

What conditions does trial NCT06116630 study?

This clinical trial studies the following conditions: Stroke.

What interventions are being tested in trial NCT06116630?

The interventions under investigation include: DCE-MRI (DIAGNOSTIC_TEST).

Who is sponsoring clinical trial NCT06116630?

This trial is sponsored by Stanford University, which has 1,744 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06116630 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Learn More About Clinical Trials

Similar trials for Stroke

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT06116630's enrollment target sits among peer trials

350 71st of 454 higher than 382 of 454 other Stroke trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Stroke trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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More recruiting context for NCT06116630

Source: ClinicalTrials.gov NCT06116630, the US trial registry maintained by the National Library of Medicine. NCT06116630 (mid enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.