Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT05147792 · ClinicalTrials.gov registry record · NA
The CONFORM Pivotal Trial
A NA study of Stroke and Atrial Fibrillation, sponsored by Conformal Medical.
- Recruiting
- Registry status
- NA
- Development phase
- 1,600
- Enrollment target
- 20
- Study locations
NCT05147792: Recruiting NA study of Stroke and Atrial Fibrillation, sponsored by Conformal Medical.
NCT05147792 is a NA study of Stroke and Atrial Fibrillation that is actively recruiting participants, run by Conformal Medical. The registered enrollment target is 1,600 participants, below the 12,013-participant average among 454 other Stroke trials with a reported enrollment target (87% lower). The trial reports 20 study locations across 7 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05147792, a NA study of Stroke and Atrial Fibrillation, is actively recruiting participants, sponsored by Conformal Medical.
- RECRUITING
- Registry status
- NA
- Development phase
- 1,600 participants
- Enrollment target
- 20
- Study locations
Study Summary
The CLAAS® device will be evaluated for safety and efficacy by establishing its performance is non-inferior to the commercially available WATCHMAN® and Amulet™ left atrial appendage closure devices in patients with non-valvular atrial fibrillation. Patients who are eligible for the trial will be randomized to receive either the CLAAS device or the WATCHMAN or Amulet™ devices and will be followed for 5 years after device implant.
Conditions Studied
Interventions
- DEVICE CLAAS
- DEVICE WATCHMAN left atrial appendage closure device / Amulet left atrial appendage occluder
Study Locations (20)
Florida
- Ascension St. Vincent's Jacksonville - Jacksonville
- Largo Medical Center - Largo
- Baptist Hospital of Miami - Miami
- AdventHealth Orlando - Orlando
- Baptist Health Care - Pensacola - Pensacola
- Sarasota Memorial Health Care System - Sarasota
- AdventHealth Tampa - Tampa
- USF - Tampa General Hospital - Tampa
Arizona
- Banner University Medical Center Phoenix - Phoenix
- Abrazo Arizona Heart Hospital - Phoenix
- HonorHealth - Scottsdale
- Pima Heart & Vascular - Tucson
California
- Loma Linda University Health - Loma Linda
- Huntington Hospital - Pasadena
- Pacific Heart Institute - Santa Monica
- Community Memorial Hospital Ventura - Ventura
Alabama
- Grandview Medical Center - Birmingham
Arkansas
- St. Bernard's Medical Center - Jonesboro
Connecticut
- Hartford Health Care St. Vincent's Medical Center - Bridgeport
District of Columbia
- MedStar Washington Hospital Center - Washington D.C.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1,600 participants |
| Start Date | 2022-05-26 |
| Est. Completion | 2031-12 |
| Phase | NA |
What NCT05147792 shows while recruiting
NCT05147792 is an interventional study that assigns participants to a tested intervention. Its 1,600 participants enrollment target places it among the larger protocols in the corpus, below the 12,013-participant average among 454 other Stroke trials with a reported enrollment target (87% lower).
The record links to 2 conditions, with Stroke appearing as the primary indexed condition, and to 2 interventions - of which CLAAS is the first listed.
NCT05147792 names 20 study sites across 7 states, led by Florida, Arizona, California.
Frequently Asked Questions
What is clinical trial NCT05147792 about?
NCT05147792 is a clinical study titled "The CONFORM Pivotal Trial". The CLAAS® device will be evaluated for safety and efficacy by establishing its performance is non-inferior to the commercially available WATCHMAN® and Amulet™ left atrial appendage closure devices in patients with non-valvular atrial fibrillation. Patients who are eligible for the trial will be ran...
What is the current status of trial NCT05147792?
This trial is currently recruiting. It is a NA study. The enrollment target is 1,600 participants. The study started on 2022-05-26. Estimated completion is 2031-12.
What conditions does trial NCT05147792 study?
This clinical trial studies the following conditions: Stroke, Atrial Fibrillation.
What interventions are being tested in trial NCT05147792?
The interventions under investigation include: CLAAS (DEVICE), WATCHMAN left atrial appendage closure device / Amulet left atrial appendage occluder (DEVICE).
Who is sponsoring clinical trial NCT05147792?
This trial is sponsored by Conformal Medical, which has 2 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05147792 being conducted?
This trial has 20 study locations across Alabama, Arizona, Arkansas, California, Connecticut. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Stroke
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05147792's enrollment target sits among peer trials
1,600 30th of 454 higher than 425 of 454 other Stroke trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Stroke trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Tracking a Tactile Signal Along the Nervous System
RECRUITING · NA
-
Transcranial Direct Current Stimulation (tDCS) With Verb Network Strengthening Treatment (VNeST) in Chronic Aphasia
RECRUITING · NA
-
Strategy Training for Individuals With Unilateral Neglect
RECRUITING · NA
-
Weight Loss and ExeRcise
RECRUITING · NA
-
Safety and Feasibility of an ExoNET for Supination Assistance for Stroke Survivors
RECRUITING · NA
-
Deep Brain Stimulation Motor Ventral Thalamus (VOP/VIM) for Restoration of Speech and Upper-limb Function in People With Subcortical Stroke
RECRUITING · NA
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT00646022 · 1,600 participants
Natural History of Familial Carcinoid Tumor
- NCT03109197 · 1,600 participants
Sudden Unexplained Death in Childhood (SUDC) Registry
- NCT03511118 · 1,600 participants
Pharmacokinetics and Safety of Commonly Used Drugs in Lactating Women and Breastfed Infants
- NCT04314401 · 1,600 participants
National Cancer Institute "Cancer Moonshot Biobank"
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI