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NCT05276050 · ClinicalTrials.gov registry record · NA
Circuitry-Guided Smoking Cessation in Schizophrenia (UH3)
A NA study of Schizophrenia and Smoking Cessation, sponsored by The University of Texas Health Science Center, Houston.
- Recruiting
- Registry status
- NA
- Development phase
- 50
- Enrollment target
- 1
- Study location
NCT05276050: Recruiting NA study of Schizophrenia and Smoking Cessation, sponsored by The University of Texas Health Science Center, Houston.
NCT05276050 is a NA study of Schizophrenia and Smoking Cessation that is actively recruiting participants, run by The University of Texas Health Science Center, Houston. The registered enrollment target is 50 participants, below the 219-participant average among 315 other Schizophrenia trials with a reported enrollment target (77% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05276050, a NA study of Schizophrenia and Smoking Cessation, is actively recruiting participants, sponsored by The University of Texas Health Science Center, Houston.
- RECRUITING
- Registry status
- NA
- Development phase
- 50 participants
- Enrollment target
- 1
- Study location
Study Summary
Patients with schizophrenia spectrum disorder (SSD) will be exposed to active repetitive transcranial magnetic stimulation (rTMS) from F8 coil or active rTMS from H coil for smoking cessation. Smoking and brain functional connectivity changes will be assessed at baseline, different stages of rTMS and/or follow-ups.
Primary Outcome
The strength of rsFC from fMRI is used to represent the brain activities that are corresponding to the TMS effect on smoking reduction/cessation.
Conditions Studied
Interventions
- DEVICE active H-coil delivered rTMS
- DEVICE active F8-coil delivered rTMS
Study Locations (1)
Texas
- The University of Texas Health Science Center, Houston - Houston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 50 participants |
| Start Date | 2022-06-01 |
| Est. Completion | 2027-01-30 |
| Phase | NA |
What NCT05276050 shows while recruiting
NCT05276050 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 50 participants, a relatively small participant target, below the 219-participant average among 315 other Schizophrenia trials with a reported enrollment target (77% lower).
The record links to 3 conditions, with Schizophrenia appearing as the primary indexed condition, and to 2 interventions - of which active H-coil delivered rTMS is the first listed.
NCT05276050 reports a single indexed study location in Texas.
Frequently Asked Questions
What is clinical trial NCT05276050 about?
NCT05276050 is a clinical study titled "Circuitry-Guided Smoking Cessation in Schizophrenia (UH3)". Patients with schizophrenia spectrum disorder (SSD) will be exposed to active repetitive transcranial magnetic stimulation (rTMS) from F8 coil or active rTMS from H coil for smoking cessation. Smoking and brain functional connectivity changes will be assessed at baseline, different stages of rTMS an...
What is the current status of trial NCT05276050?
This trial is currently recruiting. It is a NA study. The enrollment target is 50 participants. The study started on 2022-06-01. Estimated completion is 2027-01-30.
What conditions does trial NCT05276050 study?
This clinical trial studies the following conditions: Schizophrenia, Smoking Cessation, Nicotine Addiction.
What interventions are being tested in trial NCT05276050?
The interventions under investigation include: active H-coil delivered rTMS (DEVICE), active F8-coil delivered rTMS (DEVICE).
Who is sponsoring clinical trial NCT05276050?
This trial is sponsored by The University of Texas Health Science Center, Houston, which has 732 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05276050 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Schizophrenia
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05276050's enrollment target sits among peer trials
50 208th of 315 higher than 101 of 315 other Schizophrenia trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Schizophrenia trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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