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Sleep Apnea, Obstructive: early-phase trial registry
14 of 46 indexed Sleep Apnea, Obstructive trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #312 of 28,707 conditions by registered trial count.
46 US clinical trials · 14 currently recruiting · #312 of 28,707 conditions by registered trial count
Sleep Apnea, Obstructive: 46 US clinical trials tracked, 14 recruiting.
Sleep Apnea, Obstructive is the subject of 46 registered US clinical trials on ClinicalTrials.gov, 14 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 7 in Phase 1-2 (earlier-stage). The most active sponsor is University of Michigan, running 5 of these trials.
Enrollment posture brief
Registry condition sleep-apnea-obstructive
OPEN 14 | RECR 30% | LATE 2 | EARLY 7 | RANK #312 | SPON 5
Volume-matched condition peers
Nearest open-share peer: Anxiety Disorder (30% recruiting · 23 trials)
Sleep Apnea, Obstructive lists 14 open slots (30% of 46 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Sleep Apnea, Obstructive on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Sleep Apnea, Obstructive is recruiting below its size-band peers.
14 of 46 indexed trials (30.4%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Sleep Apnea, Obstructive trials is spread across many organizations.
University of Michigan accounts for 5 of 46 trials (10.9%). 33 distinct sponsors appear on at least one study for this condition label.
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Typical Sleep Apnea, Obstructive enrolment sits around 60 participants.
Median target enrolment is 60 among the 46 trials that report a genuine target (sentinel values excluded). 27 of those (58.7%) plan for fewer than 100 participants.
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Sleep Apnea, Obstructive research is mostly interventional.
38 interventional and 8 observational studies make up this index (82.6% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
46 total, page 1 of 1
Effects of CPAP Therapy on Blood Pressure and Heart Rate Variability in Obstructive Sleep Apnea
Ohio State University
NCT04712656
A Study of Eloralintide (LY3841136) in Participants With Obstructive Sleep Apnea and Obesity or Overweight
Eli Lilly and Company
NCT07369011
Drug-Induced Sleep Endoscopy for Upper Airway Evaluation in Obstructive Sleep Apnea
University of California, Los Angeles
NCT00695214
Home Apnea Testing in CHildren Trial
Children's Hospital of Philadelphia
NCT05382754
The PREDICTOR Study: Assessing Diagnostic Predictors of Airway Collapse in Patients With Obstructive Sleep Apnea
Inspire Medical Systems
NCT05428839
Do Endotypes Predict Response and Sequelae in OSA Patients
University of California, San Diego
NCT04875364
Lateral Pharyngoplasty Outcomes in Children Undergoing Tonsillectomy
Loma Linda University
NCT05575401
The REPOSE (Reach for Equity in Pediatric Sleep Evaluation) Navigation Intervention
Medical University of South Carolina
NCT06828835
Predicting Outcomes in Hypoglossal Nerve Stimulation Therapy With Stimulated Upper Airway Mechanics
Johns Hopkins University
NCT05429983
Nasal vs Oral Breathing in Drug Induced Sleep vs Natural Sleep
University of Pennsylvania
NCT06789770
Benefits of Oxytocin in Obstructive Sleep Apnea (OSA) Patients Using Continuous Positive Airway Pressure (CPAP) Machine
Vivek Jain
NCT03860233
Type 1 Diabetes and Obstructive Sleep Apnea
University of Chicago
NCT06915831
NPA-OSA Device Tolerability, Usability and Acclimation Clinical Study in Adult Obstructive Sleep Apnea (OSA) Patients
University of Michigan
NCT06677151
Long-term Evaluation of a Nasopharyngeal Airway
University of Michigan
NCT07191314
Sleep for Stroke Management and Recovery Trial
University of Michigan
NCT03812653
Study Using Negative Pressure to Reduce Apnea
Sommetrics
NCT04861038
Therapist-Directed VS Online Therapy for Insomnia Co-Occuring With Sleep Apnea
National Jewish Health
NCT03109210
MCI: CPAP Treatment of OSA (Memories2)
University of Pennsylvania
NCT03113461
Safety and Effectiveness of the Genio® bilAteral Stimulation for Treatment of Complete Concentric CollapsE and OSA.
Nyxoah S.A.
NCT05592002
Pragmatic Obstructive Sleep Apnea Weight Loss Trial Assessing Effectiveness and Reach
VA Office of Research and Development
NCT05104450
Evaluating Behavioral Treatments to Improve Adherence to Continuous Positive Airway Pressure (CPAP) Therapy in People With Obstructive Sleep Apnea (The BREATHE Study)
National Jewish Health
NCT00623246
Prevalence of Sleep Apnea in Patients Presenting for Hip or Knee Replacement Surgery
University of Nebraska
NCT00874822
Comparative Outcomes Management With Electronic Data Technology (COMET) Study
Stanford University
NCT01461473
Tailored Intervention to Promote Positive Airway Pressure Adherence
Milton S. Hershey Medical Center
NCT01454830
Behavioral Effects of Obstructive Sleep Apnea in Children
University of Michigan
NCT00060723
Safety Study of Quickclot for Bleeding Control After Adenotonsillectomy
Eastern Virginia Medical School
NCT01863563
"Reversibility of Cardiovascular Injury With CPAP Use: Mechanisms Involved"
University of Wisconsin, Madison
NCT01317329
Evaluation of An Optical Measurement Algorithm Combined With Patient and Provider Input to Reduce Mask Exchanges During Initial Positive Airway Pressure Therapy
Mayo Clinic
NCT04688125
Evaluating an Under-mattress Sleep Monitor Compared to a Peripheral Arterial Tonometry Device in the Diagnosis of Obstructive Sleep Apnea
Mayo Clinic
NCT04778748
COMMunication and Education for the New CPAP Experience
University of Pittsburgh
NCT01377584
Dexmedetomidine and Propofol in Children With History of Obstructive Sleep Apnea
Children's Hospital Medical Center, Cincinnati
NCT01344759
A Pilot Study to Evaluate the Hypoglossal Nerve Stimulator in Adolescents With Down Syndrome and Obstructive Sleep Apnea
Christopher Hartnick, M.D.
NCT02344108
Group-based Peer Support Versus Individual Education for Patients Undergoing CPAP Treatment
Brigham and Women's Hospital
NCT02538419
Evaluation of an Algorithm to Detect Sleep and Wake in Continuous Positive Airway Pressure (CPAP)
Philips Respironics
NCT01031914
Positive Airway Pressure Program
Fisher and Paykel Healthcare
NCT02331992
Auto Continuous Positive Airway Pressure (CPAP) Based Energy Spectrum Analysis of Flow for Treatment of Obstructive Sleep Apnea Hypopnea Syndrome (OSAHS)
Fisher and Paykel Healthcare
NCT00750165
Motor Plasticity, Intermittent Hypoxia and Sleep Apnea
University of Miami
NCT04017767
Safety of Ramelteon in Subjects With Mild to Moderate Obstructive Sleep Apnea
Takeda
NCT00672061
Titration Pressures in Sleep Apnea Patients Using ThermoSmart® Versus Conventional Humidification
Fisher and Paykel Healthcare
NCT00681083
Characterizing Upper Airway Collapse to Guide Patient Selection for Oral Appliance Therapy for Obstructive Sleep Apnea
Brigham and Women's Hospital
NCT02489591
Oxygen Saturation Monitoring During Surgery
Medtronic - MITG
NCT01098851
Feasibility of Improving Sleep Apnea Treatment Adherence After Brain Injury
VA Office of Research and Development
NCT04221009
Effect of Desipramine on Upper Airway Collapsibility and Genioglossus Muscle Activity in Patients With Obstructive Sleep Apnea - Study B
Brigham and Women's Hospital
NCT02436031
Evaluation of Hypoglossal Nerve Stimulation in Humans With Obstructive Sleep Apnea
Invicta Medical
NCT06283030
Sleep Apnea Treatment With Expiratory Resistance(Provent™)
Johns Hopkins University
NCT01061476
Pilot Study of a Self-Supporting Nasopharyngeal Airway in Hypotonia
University of Michigan
NCT04846400
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 3 |
| Phase 2 | 4 |
| Phase 3 | 1 |
| Phase 4 | 1 |
Top Sponsors
Named interventions
Most-linked intervention names on Sleep Apnea, Obstructive records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Sleep Apnea, Obstructive trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Sleep Apnea, Obstructive page
46 registered trials, 14 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 14 Sleep Apnea, Obstructive trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- University of Michigan sponsors the most Sleep Apnea, Obstructive trials on record, review their full trial history before evaluating a specific study. See University of Michigan's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Sleep Apnea, Obstructive condition card totals 46 registered trials; most-linked intervention Placebo; top US site state Pennsylvania. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.