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Sleep Apnea, Obstructive
Open-data reference.
46 US clinical trials · 14 currently recruiting
Active & Recent Trials
Effects of CPAP Therapy on Blood Pressure and Heart Rate Variability in Obstructive Sleep Apnea
Ohio State University
NCT04712656
A Study of Eloralintide (LY3841136) in Participants With Obstructive Sleep Apnea and Obesity or Overweight
Eli Lilly and Company
NCT07369011
Drug-Induced Sleep Endoscopy for Upper Airway Evaluation in Obstructive Sleep Apnea
University of California, Los Angeles
NCT00695214
Home Apnea Testing in CHildren Trial
Children's Hospital of Philadelphia
NCT05382754
The PREDICTOR Study: Assessing Diagnostic Predictors of Airway Collapse in Patients With Obstructive Sleep Apnea
Inspire Medical Systems
NCT05428839
Do Endotypes Predict Response and Sequelae in OSA Patients
University of California, San Diego
NCT04875364
Lateral Pharyngoplasty Outcomes in Children Undergoing Tonsillectomy
Loma Linda University
NCT05575401
The REPOSE (Reach for Equity in Pediatric Sleep Evaluation) Navigation Intervention
Medical University of South Carolina
NCT06828835
Predicting Outcomes in Hypoglossal Nerve Stimulation Therapy With Stimulated Upper Airway Mechanics
Johns Hopkins University
NCT05429983
Nasal vs Oral Breathing in Drug Induced Sleep vs Natural Sleep
University of Pennsylvania
NCT06789770
Benefits of Oxytocin in Obstructive Sleep Apnea (OSA) Patients Using Continuous Positive Airway Pressure (CPAP) Machine
Vivek Jain
NCT03860233
Type 1 Diabetes and Obstructive Sleep Apnea
University of Chicago
NCT06915831
NPA-OSA Device Tolerability, Usability and Acclimation Clinical Study in Adult Obstructive Sleep Apnea (OSA) Patients
University of Michigan
NCT06677151
Long-term Evaluation of a Nasopharyngeal Airway
University of Michigan
NCT07191314
Sleep for Stroke Management and Recovery Trial
University of Michigan
NCT03812653
Study Using Negative Pressure to Reduce Apnea
Sommetrics
NCT04861038
Therapist-Directed VS Online Therapy for Insomnia Co-Occuring With Sleep Apnea
National Jewish Health
NCT03109210
MCI: CPAP Treatment of OSA (Memories2)
University of Pennsylvania
NCT03113461
Safety and Effectiveness of the Genio® bilAteral Stimulation for Treatment of Complete Concentric CollapsE and OSA.
Nyxoah S.A.
NCT05592002
Pragmatic Obstructive Sleep Apnea Weight Loss Trial Assessing Effectiveness and Reach
VA Office of Research and Development
NCT05104450
Evaluating Behavioral Treatments to Improve Adherence to Continuous Positive Airway Pressure (CPAP) Therapy in People With Obstructive Sleep Apnea (The BREATHE Study)
National Jewish Health
NCT00623246
Prevalence of Sleep Apnea in Patients Presenting for Hip or Knee Replacement Surgery
University of Nebraska
NCT00874822
Comparative Outcomes Management With Electronic Data Technology (COMET) Study
Stanford University
NCT01461473
Tailored Intervention to Promote Positive Airway Pressure Adherence
Milton S. Hershey Medical Center
NCT01454830
Behavioral Effects of Obstructive Sleep Apnea in Children
University of Michigan
NCT00060723
Safety Study of Quickclot for Bleeding Control After Adenotonsillectomy
Eastern Virginia Medical School
NCT01863563
"Reversibility of Cardiovascular Injury With CPAP Use: Mechanisms Involved"
University of Wisconsin, Madison
NCT01317329
Evaluation of An Optical Measurement Algorithm Combined With Patient and Provider Input to Reduce Mask Exchanges During Initial Positive Airway Pressure Therapy
Mayo Clinic
NCT04688125
Evaluating an Under-mattress Sleep Monitor Compared to a Peripheral Arterial Tonometry Device in the Diagnosis of Obstructive Sleep Apnea
Mayo Clinic
NCT04778748
COMMunication and Education for the New CPAP Experience
University of Pittsburgh
NCT01377584
Dexmedetomidine and Propofol in Children With History of Obstructive Sleep Apnea
Children's Hospital Medical Center, Cincinnati
NCT01344759
A Pilot Study to Evaluate the Hypoglossal Nerve Stimulator in Adolescents With Down Syndrome and Obstructive Sleep Apnea
Christopher Hartnick, M.D.
NCT02344108
Group-based Peer Support Versus Individual Education for Patients Undergoing CPAP Treatment
Brigham and Women's Hospital
NCT02538419
Evaluation of an Algorithm to Detect Sleep and Wake in Continuous Positive Airway Pressure (CPAP)
Philips Respironics
NCT01031914
Positive Airway Pressure Program
Fisher and Paykel Healthcare
NCT02331992
Auto Continuous Positive Airway Pressure (CPAP) Based Energy Spectrum Analysis of Flow for Treatment of Obstructive Sleep Apnea Hypopnea Syndrome (OSAHS)
Fisher and Paykel Healthcare
NCT00750165
Motor Plasticity, Intermittent Hypoxia and Sleep Apnea
University of Miami
NCT04017767
Safety of Ramelteon in Subjects With Mild to Moderate Obstructive Sleep Apnea
Takeda
NCT00672061
Titration Pressures in Sleep Apnea Patients Using ThermoSmart® Versus Conventional Humidification
Fisher and Paykel Healthcare
NCT00681083
Characterizing Upper Airway Collapse to Guide Patient Selection for Oral Appliance Therapy for Obstructive Sleep Apnea
Brigham and Women's Hospital
NCT02489591
Oxygen Saturation Monitoring During Surgery
Medtronic - MITG
NCT01098851
Feasibility of Improving Sleep Apnea Treatment Adherence After Brain Injury
VA Office of Research and Development
NCT04221009
Effect of Desipramine on Upper Airway Collapsibility and Genioglossus Muscle Activity in Patients With Obstructive Sleep Apnea - Study B
Brigham and Women's Hospital
NCT02436031
Evaluation of Hypoglossal Nerve Stimulation in Humans With Obstructive Sleep Apnea
Invicta Medical
NCT06283030
Sleep Apnea Treatment With Expiratory Resistance(Provent™)
Johns Hopkins University
NCT01061476
Pilot Study of a Self-Supporting Nasopharyngeal Airway in Hypotonia
University of Michigan
NCT04846400
Phase Distribution
| Phase | Trial count |
|---|---|
| Early Phase 1 | 3 |
| Phase 2 | 4 |
| Phase 3 | 1 |
| Phase 4 | 1 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Sleep Apnea, Obstructive Trial Landscape
ClinicalTrials.gov lists 46 US studies indexed under Sleep Apnea, Obstructive, and 14 of those are currently open to recruitment — roughly 30% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Sleep Apnea, Obstructive shows 2 late-stage studies (Phase 3 and Phase 4 combined) alongside 7 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Sleep Apnea, Obstructive is led by University of Michigan with 5 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 46 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Sleep Apnea, Obstructive?
PlainTrial tracks 46 US clinical trials for Sleep Apnea, Obstructive, of which 14 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Sleep Apnea, Obstructive?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.