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NCT03860233 · ClinicalTrials.gov registry record · Phase 1
Benefits of Oxytocin in Obstructive Sleep Apnea (OSA) Patients Using Continuous Positive Airway Pressure (CPAP) Machine
A Phase 1 study of Sleep Apnea, Obstructive and Sleep Apnea, sponsored by Vivek Jain.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 40
- Enrollment target
- 1
- Study location
NCT03860233: Recruiting Phase 1 study of Sleep Apnea, Obstructive and Sleep Apnea, sponsored by Vivek Jain.
NCT03860233 is a Phase 1 study of Sleep Apnea, Obstructive and Sleep Apnea that is actively recruiting participants, run by Vivek Jain. The registered enrollment target is 40 participants, below the 261-participant average among 45 other Sleep Apnea, Obstructive trials with a reported enrollment target (85% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03860233, a Phase 1 study of Sleep Apnea, Obstructive and Sleep Apnea, is actively recruiting participants, sponsored by Vivek Jain.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 40 participants
- Enrollment target
- 1
- Study location
Study Summary
This study will investigate if an intra-nasal nose spray of the drug oxytocin can decrease the amount of pressure needed from the automatic Continuous Positive Airway Pressure (CPAP) device while sleeping decreasing some of the harmful effects of low oxygen in people with sleep apnea. This study will last 35 nights and involves spending three nights in the sleep lab at George Washington University. There are no additional costs to participants and no compensation for being involved in the study.
Primary Outcome
CPAP pressures will be monitored during study via electronic data retrieval system
Conditions Studied
Interventions
- DRUG Placebo
- DRUG Oxytocin
Study Locations (1)
District of Columbia
- Medical Faculty Associates - Washington D.C.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2019-03-04 |
| Est. Completion | 2026-03-01 |
| Phase | Phase 1 |
What NCT03860233 shows while recruiting
NCT03860233 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 261-participant average among 45 other Sleep Apnea, Obstructive trials with a reported enrollment target (85% lower).
The record links to 2 conditions, with Sleep Apnea, Obstructive appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT03860233 reports a single indexed study location in District of Columbia.
Frequently Asked Questions
What is clinical trial NCT03860233 about?
NCT03860233 is a clinical study titled "Benefits of Oxytocin in Obstructive Sleep Apnea (OSA) Patients Using Continuous Positive Airway Pressure (CPAP) Machine". This study will investigate if an intra-nasal nose spray of the drug oxytocin can decrease the amount of pressure needed from the automatic Continuous Positive Airway Pressure (CPAP) device while sleeping decreasing some of the harmful effects of low oxygen in people with sleep apnea. This study wi...
What is the current status of trial NCT03860233?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 40 participants. The study started on 2019-03-04. Estimated completion is 2026-03-01.
What conditions does trial NCT03860233 study?
This clinical trial studies the following conditions: Sleep Apnea, Obstructive, Sleep Apnea.
What interventions are being tested in trial NCT03860233?
The interventions under investigation include: Placebo (DRUG), Oxytocin (DRUG).
Who is sponsoring clinical trial NCT03860233?
This trial is sponsored by Vivek Jain, which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03860233 being conducted?
This trial has 1 study location across District of Columbia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Sleep Apnea, Obstructive
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT03860233's enrollment target sits among peer trials
40 29th of 45 higher than 15 of 45 other Sleep Apnea, Obstructive trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Sleep Apnea, Obstructive trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Tailored Intervention to Promote Positive Airway Pressure Adherence
COMPLETED · Phase 1
-
Sleep Apnea Treatment With Expiratory Resistance(Provent™)
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Nasal vs Oral Breathing in Drug Induced Sleep vs Natural Sleep
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Do Endotypes Predict Response and Sequelae in OSA Patients
RECRUITING · Phase 2
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The PREDICTOR Study: Assessing Diagnostic Predictors of Airway Collapse in Patients With Obstructive Sleep Apnea
RECRUITING · NA
-
A Study of Eloralintide (LY3841136) in Participants With Obstructive Sleep Apnea and Obesity or Overweight
RECRUITING · Phase 3
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