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NCT01344759 · ClinicalTrials.gov registry record · Phase 4
Dexmedetomidine and Propofol in Children With History of Obstructive Sleep Apnea
A Phase 4 study of Sleep Apnea, Obstructive, sponsored by Children's Hospital Medical Center, Cincinnati.
- Completed
- Registry status
- Phase 4
- Development phase
- 60
- Enrollment target
- 1
- Study location
NCT01344759: Completed Phase 4 study of Sleep Apnea, Obstructive, sponsored by Children's Hospital Medical Center, Cincinnati.
NCT01344759 is a Phase 4 study of Sleep Apnea, Obstructive that has completed, run by Children's Hospital Medical Center, Cincinnati. The registered enrollment target is 60 participants, below the 261-participant average among 45 other Sleep Apnea, Obstructive trials with a reported enrollment target (77% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01344759, a Phase 4 study of Sleep Apnea, Obstructive, has completed, sponsored by Children's Hospital Medical Center, Cincinnati.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 60 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this research study is to examine the effects of two commonly used anesthetic drugs, dexmedetomidine and propofol, have on the shape and muscle tone of the upper airway in children, adolescents, and young adults with a history of obstructive sleep apnea (OSA) having an MRI scan. The results of this study will help in making the best decisions regarding the anesthesia medications that are most appropriate for children, adolescents, and young adults with OSA during MRI studies.
Primary Outcome
The primary outcome measures will be the cross sectional area of the pharyngeal airway of the patients measured at two levels soft palate (nasopharyngeal) and base of the tongue (retroglossal). Magnetic resonance images of the airway were obtained during low (1 mcg/kg/hr) and high (3 mcg/kg/hr) doses of DEX or low (100 mcg/kg/m) and high (200 mcg/kg/m) doses of Propofol. All were administered through an intravenous (IV) catheter.
Conditions Studied
Interventions
- DRUG Dexmedetomidine
- DRUG Propofol
Study Locations (1)
Ohio
- Cincinnati Children's Hospital Medical Center - Cincinnati
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2009-06 |
| Est. Completion | 2011-11 |
| Phase | Phase 4 |
What the finished NCT01344759 record still lists
NCT01344759 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 60 participants, a relatively small participant target, below the 261-participant average among 45 other Sleep Apnea, Obstructive trials with a reported enrollment target (77% lower).
The record links to 1 condition, with Sleep Apnea, Obstructive appearing as the primary indexed condition, and to 2 interventions - of which Dexmedetomidine is the first listed.
NCT01344759 reports a single indexed study location in Ohio.
Frequently Asked Questions
What is clinical trial NCT01344759 about?
NCT01344759 is a clinical study titled "Dexmedetomidine and Propofol in Children With History of Obstructive Sleep Apnea". The purpose of this research study is to examine the effects of two commonly used anesthetic drugs, dexmedetomidine and propofol, have on the shape and muscle tone of the upper airway in children, adolescents, and young adults with a history of obstructive sleep apnea (OSA) having an MRI scan. The ...
What is the current status of trial NCT01344759?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 60 participants. The study started on 2009-06. Estimated completion is 2011-11.
What conditions does trial NCT01344759 study?
This clinical trial studies the following conditions: Sleep Apnea, Obstructive.
What interventions are being tested in trial NCT01344759?
The interventions under investigation include: Dexmedetomidine (DRUG), Propofol (DRUG).
Who is sponsoring clinical trial NCT01344759?
This trial is sponsored by Children's Hospital Medical Center, Cincinnati, which has 571 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01344759 being conducted?
This trial has 1 study location across Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Sleep Apnea, Obstructive
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT01344759's enrollment target sits among peer trials
60 23rd of 45 higher than 20 of 45 other Sleep Apnea, Obstructive trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Sleep Apnea, Obstructive trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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