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Schizoaffective Disorder clinical trials
19 of 83 indexed Schizoaffective Disorder trials are currently recruiting.
83 US clinical trials · 19 currently recruiting
Schizoaffective Disorder is the subject of 83 registered US clinical trials on ClinicalTrials.gov, 19 of them currently open to new participants. 18 are in Phase 3-4 (later-stage) and 14 in Phase 1-2 (earlier-stage). The most active sponsor is University of Maryland, Baltimore, running 6 of these trials.
The research picture
Schizoaffective Disorder has 83 registered US clinical trials, 19 of them open to new participants right now, about 23% of the total.
- 19
- recruiting participants now
- 23%
- of trials open to enrollment
- 18
- in Phase 3–4 (later-stage)
- 6
- top sponsor: University of Maryland, Baltimore
Active & Recent Trials
83 total, page 2 of 2
Cognitive Training for Patients With Schizophrenia
University of California, San Diego
NCT01521026
Improving Accessibility and Personalization of CR for Schizophrenia
New York State Psychiatric Institute
NCT03576976
Double-Blind Trial of a Probiotic Supplement to Reduce the Symptoms of Schizophrenia
Sheppard Pratt Health System
NCT01242371
Determining the Effects of Risperdal Consta in Patients With Psychotic Disorders and Incomplete Adherence
Duke University
NCT00215579
Memantine Augmentation of Targeted Cognitive Training in Schizophrenia
University of California, San Diego
NCT04857983
The Effect of N-Acetyl Cysteine on Cortical Erosion in Early Stage Schizophrenia
Indiana University
NCT01339858
High Dose of Quetiapine in Treating Subjects With Treatment Refractory Schizophrenia or Schizoaffective Disorder
Manhattan Psychiatric Center
NCT00297947
Development of a Mobile System for Self-management of Schizophrenia (SOS)
Dartmouth-Hitchcock Medical Center
NCT01969500
Controlled Trial of Brexpiprazole For The Treatment of Co-occurring Schizophrenia and Substance Use Disorder
University of Massachusetts, Worcester
NCT03526354
Omega-3 Dietary Supplements in Schizophrenia
Delbert Robinson
NCT01786239
Effectiveness of a Mobile Texting Intervention for People With Serious Mental Illness
University of Washington
NCT03062267
Enhancing Cognitive Training Through Exercise After a First Schizophrenia Episode
University of California, Los Angeles
NCT02267070
A Study to Determine Pharmacokinetic Characteristics of LY03010 Versus INVEGA SUSTENNA® in Schizophrenia Patients
Luye Pharma Group
NCT03751488
A Study of Aripiprazole Lauroxil in Subjects With Schizophrenia or Schizoaffective Disorder
Alkermes
NCT02636842
Texting for Relapse Prevention
Center for Innovative Public Health Research
NCT02819349
A Comparison of Two Cognitive Batteries in People With Schizophrenia
North Suffolk Mental Health Association
NCT00499044
Motivation and Skills Support (MASS)
Boston University Charles River Campus
NCT03404219
A Concierge Model of CAE Plus LAI in Individuals With Schizophrenia at Risk for Treatment Non-adherence and Homelessness
University Hospitals Cleveland Medical Center
NCT02085447
Prebiotic Treatment in People With Schizophrenia - Pilot Study
University of Maryland, Baltimore
NCT03617783
Ramelteon as an Adjunct Therapy in Non-Diabetic Patients With Schizophrenia
Massachusetts General Hospital
NCT00595504
Pilot Trial of Naltrexone for Obesity in Women With Schizophrenia
Yale University
NCT00793780
Neuroendocrine and Immune Response to Stress in Schizophrenia
University of Maryland, Baltimore
NCT01975584
NST-SPARK: Preliminary Study of an Augmented Reality (AR) App Delivering Recovery-Oriented Cognitive Therapy for Negative Symptoms in Schizophrenia
North Shore Therapeutics
NCT06653829
Galantamine for Cognition in People With Schizophrenia
North Suffolk Mental Health Association
NCT00320736
Effects of Pentazocine Versus Lorazepam on Manic Symptoms
Mclean Hospital
NCT00431184
M1 Schizophrenia PET Study
Yale University
NCT05105542
Biomarkers in Schizophrenia
Nathan Kline Institute for Psychiatric Research
NCT00817336
An Randomized Open-Label PK Study of LY03004 Compared to Risperdal® Consta® in Stable Patients With Schizophrenia or Schizoaffective Disorder
Luye Pharma Group
NCT02186769
Effects of Antipsychotic Medications on Energy Intake and Expenditure
Washington University School of Medicine
NCT00836251
Family-Directed Cognitive Adaptation Program for Individuals With Schizophrenia
Beth Israel Deaconess Medical Center
NCT00434980
eMove - Dance/Movement Therapy Study
Drexel University
NCT05712928
Improving Neurocognitive Deficits and Function in Schizophrenia With Transcranial Magnetic Stimulation
VA Office of Research and Development
NCT03037983
Generalization of Training in Schizophrenia
US Department of Veterans Affairs
NCT00108199
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 6 |
| Phase 2 | 8 |
| Phase 3 | 4 |
| Phase 4 | 14 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Schizoaffective Disorder Trial Landscape
83 indexed Schizoaffective Disorder studies · 19 recruiting (23%).
Phase mix: 18 late (III/IV) vs 14 early (I/II).
Top sponsor: University of Maryland, Baltimore (6 trials), 9 others listed. 33 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Schizoaffective Disorder?
PlainTrial tracks 83 US clinical trials for Schizoaffective Disorder, of which 19 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Schizoaffective Disorder?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.