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ClinicalTrials.gov 19 recruiting now official registry

Schizoaffective Disorder clinical trials

19 of 83 indexed Schizoaffective Disorder trials are currently recruiting.

83 US clinical trials · 19 currently recruiting

Schizoaffective Disorder is the subject of 83 registered US clinical trials on ClinicalTrials.gov, 19 of them currently open to new participants. 18 are in Phase 3-4 (later-stage) and 14 in Phase 1-2 (earlier-stage). The most active sponsor is University of Maryland, Baltimore, running 6 of these trials.

The research picture

Schizoaffective Disorder has 83 registered US clinical trials, 19 of them open to new participants right now, about 23% of the total.

19
recruiting participants now
23%
of trials open to enrollment
18
in Phase 3–4 (later-stage)
6
top sponsor: University of Maryland, Baltimore
Phase 16Phase 28Phase 34Phase 414

Active & Recent Trials

83 total, page 2 of 2

COMPLETED NA 69 participants

Cognitive Training for Patients With Schizophrenia

University of California, San Diego

NCT01521026

COMPLETED NA 67 participants

Improving Accessibility and Personalization of CR for Schizophrenia

New York State Psychiatric Institute

NCT03576976

COMPLETED NA 65 participants

Double-Blind Trial of a Probiotic Supplement to Reduce the Symptoms of Schizophrenia

Sheppard Pratt Health System

NCT01242371

COMPLETED Phase 4 64 participants

Determining the Effects of Risperdal Consta in Patients With Psychotic Disorders and Incomplete Adherence

Duke University

NCT00215579

COMPLETED Phase 2 62 participants

Memantine Augmentation of Targeted Cognitive Training in Schizophrenia

University of California, San Diego

NCT04857983

COMPLETED Phase 4 60 participants

The Effect of N-Acetyl Cysteine on Cortical Erosion in Early Stage Schizophrenia

Indiana University

NCT01339858

COMPLETED Phase 2 60 participants

High Dose of Quetiapine in Treating Subjects With Treatment Refractory Schizophrenia or Schizoaffective Disorder

Manhattan Psychiatric Center

NCT00297947

COMPLETED NA 51 participants

Development of a Mobile System for Self-management of Schizophrenia (SOS)

Dartmouth-Hitchcock Medical Center

NCT01969500

COMPLETED Phase 4 50 participants

Controlled Trial of Brexpiprazole For The Treatment of Co-occurring Schizophrenia and Substance Use Disorder

University of Massachusetts, Worcester

NCT03526354

COMPLETED NA 50 participants

Omega-3 Dietary Supplements in Schizophrenia

Delbert Robinson

NCT01786239

COMPLETED NA 49 participants

Effectiveness of a Mobile Texting Intervention for People With Serious Mental Illness

University of Washington

NCT03062267

COMPLETED NA 48 participants

Enhancing Cognitive Training Through Exercise After a First Schizophrenia Episode

University of California, Los Angeles

NCT02267070

COMPLETED Phase 1 48 participants

A Study to Determine Pharmacokinetic Characteristics of LY03010 Versus INVEGA SUSTENNA® in Schizophrenia Patients

Luye Pharma Group

NCT03751488

COMPLETED Phase 1 47 participants

A Study of Aripiprazole Lauroxil in Subjects With Schizophrenia or Schizoaffective Disorder

Alkermes

NCT02636842

COMPLETED NA 40 participants

Texting for Relapse Prevention

Center for Innovative Public Health Research

NCT02819349

COMPLETED NA 32 participants

A Comparison of Two Cognitive Batteries in People With Schizophrenia

North Suffolk Mental Health Association

NCT00499044

COMPLETED NA 31 participants

Motivation and Skills Support (MASS)

Boston University Charles River Campus

NCT03404219

COMPLETED NA 30 participants

A Concierge Model of CAE Plus LAI in Individuals With Schizophrenia at Risk for Treatment Non-adherence and Homelessness

University Hospitals Cleveland Medical Center

NCT02085447

COMPLETED Phase 4 26 participants

Prebiotic Treatment in People With Schizophrenia - Pilot Study

University of Maryland, Baltimore

NCT03617783

COMPLETED Phase 4 25 participants

Ramelteon as an Adjunct Therapy in Non-Diabetic Patients With Schizophrenia

Massachusetts General Hospital

NCT00595504

COMPLETED NA 24 participants

Pilot Trial of Naltrexone for Obesity in Women With Schizophrenia

Yale University

NCT00793780

COMPLETED NA 21 participants

Neuroendocrine and Immune Response to Stress in Schizophrenia

University of Maryland, Baltimore

NCT01975584

COMPLETED NA 20 participants

NST-SPARK: Preliminary Study of an Augmented Reality (AR) App Delivering Recovery-Oriented Cognitive Therapy for Negative Symptoms in Schizophrenia

North Shore Therapeutics

NCT06653829

COMPLETED Phase 4 20 participants

Galantamine for Cognition in People With Schizophrenia

North Suffolk Mental Health Association

NCT00320736

COMPLETED Phase 2 19 participants

Effects of Pentazocine Versus Lorazepam on Manic Symptoms

Mclean Hospital

NCT00431184

COMPLETED Phase 1 18 participants

M1 Schizophrenia PET Study

Yale University

NCT05105542

COMPLETED Phase 2 16 participants

Biomarkers in Schizophrenia

Nathan Kline Institute for Psychiatric Research

NCT00817336

COMPLETED Phase 1 16 participants

An Randomized Open-Label PK Study of LY03004 Compared to Risperdal® Consta® in Stable Patients With Schizophrenia or Schizoaffective Disorder

Luye Pharma Group

NCT02186769

COMPLETED 15 participants

Effects of Antipsychotic Medications on Energy Intake and Expenditure

Washington University School of Medicine

NCT00836251

COMPLETED NA 11 participants

Family-Directed Cognitive Adaptation Program for Individuals With Schizophrenia

Beth Israel Deaconess Medical Center

NCT00434980

COMPLETED NA 10 participants

eMove - Dance/Movement Therapy Study

Drexel University

NCT05712928

COMPLETED NA 9 participants

Improving Neurocognitive Deficits and Function in Schizophrenia With Transcranial Magnetic Stimulation

VA Office of Research and Development

NCT03037983

COMPLETED NA

Generalization of Training in Schizophrenia

US Department of Veterans Affairs

NCT00108199

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Phase Distribution

PhaseTrial count
Phase 1 6
Phase 2 8
Phase 3 4
Phase 4 14

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Schizoaffective Disorder Trial Landscape

83 indexed Schizoaffective Disorder studies · 19 recruiting (23%).

Phase mix: 18 late (III/IV) vs 14 early (I/II).

Top sponsor: University of Maryland, Baltimore (6 trials), 9 others listed. 33 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Schizoaffective Disorder?

PlainTrial tracks 83 US clinical trials for Schizoaffective Disorder, of which 19 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Schizoaffective Disorder?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.