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NCT01242371 · ClinicalTrials.gov registry record · NA

Double-Blind Trial of a Probiotic Supplement to Reduce the Symptoms of Schizophrenia

A NA study of Schizophrenia and Schizoaffective Disorder, sponsored by Sheppard Pratt Health System.

Completed
Registry status
NA
Development phase
65
Enrollment target
1
Study location

NCT01242371: Completed NA study of Schizophrenia and Schizoaffective Disorder, sponsored by Sheppard Pratt Health System.

NCT01242371 is a NA study of Schizophrenia and Schizoaffective Disorder that has completed, run by Sheppard Pratt Health System. The registered enrollment target is 65 participants, below the 219-participant average among 315 other Schizophrenia trials with a reported enrollment target (70% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01242371, a NA study of Schizophrenia and Schizoaffective Disorder, has completed, sponsored by Sheppard Pratt Health System.

COMPLETED
Registry status
NA
Development phase
65 participants
Enrollment target
1
Study location

Study Summary

The investigators intend to explore the hypothesis that symptoms of schizophrenia may be reduced by the administration of a probiotic supplement when used in addition to standard antipsychotic medications.

Primary Outcome

The Positive and Negative Syndrome Scale (PANSS) measures psychiatric symptomatology, especially related to psychosis. The complete PANSS contains ratings for 30 symptoms, including 7 positive symptoms, 7 negative symptoms, and 16 general psychiatric symptoms. The severity of each symptom is rated on a scale ranging from 1 (minimal) to 7 (extreme); higher scores indicate increased symptomatology. Total PANSS scores include scores from all categories and range from 30 to 210 units on a scale.

Interventions

  • DIETARY_SUPPLEMENT Probiotic Supplement
  • DIETARY_SUPPLEMENT Identical-appearing Placebo

Study Locations (1)

Maryland

  • Sheppart Pratt Health System - Towson

Trial Details

FieldValue
Enrollment Target 65 participants
Start Date 2010-08
Est. Completion 2012-08
Phase NA
Sheppard Pratt Health System

10 total trials

What the finished NCT01242371 record still lists

NCT01242371 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 65 participants, a relatively small participant target, below the 219-participant average among 315 other Schizophrenia trials with a reported enrollment target (70% lower).

The record links to 2 conditions, with Schizophrenia appearing as the primary indexed condition, and to 2 interventions - of which Probiotic Supplement is the first listed.

NCT01242371 reports a single indexed study location in Maryland.

Frequently Asked Questions

What is clinical trial NCT01242371 about?

NCT01242371 is a clinical study titled "Double-Blind Trial of a Probiotic Supplement to Reduce the Symptoms of Schizophrenia". The investigators intend to explore the hypothesis that symptoms of schizophrenia may be reduced by the administration of a probiotic supplement when used in addition to standard antipsychotic medications.

What is the current status of trial NCT01242371?

This trial is currently completed. It is a NA study. The enrollment target is 65 participants. The study started on 2010-08. Estimated completion is 2012-08.

What conditions does trial NCT01242371 study?

This clinical trial studies the following conditions: Schizophrenia, Schizoaffective Disorder.

What interventions are being tested in trial NCT01242371?

The interventions under investigation include: Probiotic Supplement (DIETARY_SUPPLEMENT), Identical-appearing Placebo (DIETARY_SUPPLEMENT).

Who is sponsoring clinical trial NCT01242371?

This trial is sponsored by Sheppard Pratt Health System, which has 10 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT01242371 being conducted?

This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Schizophrenia

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT01242371's enrollment target sits among peer trials

65 184th of 315 higher than 132 of 315 other Schizophrenia trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Schizophrenia trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01242371, the US trial registry maintained by the National Library of Medicine. NCT01242371 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.