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NCT00817336 · ClinicalTrials.gov registry record · Phase 2
Biomarkers in Schizophrenia
A Phase 2 study of Schizophrenia and Schizoaffective Disorder, sponsored by Nathan Kline Institute for Psychiatric Research.
- Completed
- Registry status
- Phase 2
- Development phase
- 16
- Enrollment target
- 1
- Study location
NCT00817336: Completed Phase 2 study of Schizophrenia and Schizoaffective Disorder, sponsored by Nathan Kline Institute for Psychiatric Research.
NCT00817336 is a Phase 2 study of Schizophrenia and Schizoaffective Disorder that has completed, run by Nathan Kline Institute for Psychiatric Research. The registered enrollment target is 16 participants, below the 219-participant average among 315 other Schizophrenia trials with a reported enrollment target (93% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00817336, a Phase 2 study of Schizophrenia and Schizoaffective Disorder, has completed, sponsored by Nathan Kline Institute for Psychiatric Research.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 16 participants
- Enrollment target
- 1
- Study location
Study Summary
N-methyl-D-aspartate (NMDA)-type glutamate receptors are thought to play a pivotal role in neurocognitive dysfunction associated with schizophrenia. Further, several novel glutamate-based classes of compound are presently in development as potential novel treatments for persistent negative and cognitive symptoms. The study will assess effectiveness of a NMDA-based intervention on biomarkers related to schizophrenia as a mechanism for developing appropriate outcome batteries for future trials of novel compounds.
Primary Outcome
Positive and Negative Symptom Scale (PANSS) range 30-210
Conditions Studied
Interventions
- DRUG Placebo
- DRUG D Serine
Study Locations (1)
New York
- Nathan Kline Institute - Orangeburg
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 16 participants |
| Start Date | 2009-06 |
| Est. Completion | 2011-07 |
| Phase | Phase 2 |
What the finished NCT00817336 record still lists
NCT00817336 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 16 participants, a relatively small participant target, below the 219-participant average among 315 other Schizophrenia trials with a reported enrollment target (93% lower).
The record links to 2 conditions, with Schizophrenia appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT00817336 reports a single indexed study location in New York.
Frequently Asked Questions
What is clinical trial NCT00817336 about?
NCT00817336 is a clinical study titled "Biomarkers in Schizophrenia". N-methyl-D-aspartate (NMDA)-type glutamate receptors are thought to play a pivotal role in neurocognitive dysfunction associated with schizophrenia. Further, several novel glutamate-based classes of compound are presently in development as potential novel treatments for persistent negative and cogni...
What is the current status of trial NCT00817336?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 16 participants. The study started on 2009-06. Estimated completion is 2011-07.
What conditions does trial NCT00817336 study?
This clinical trial studies the following conditions: Schizophrenia, Schizoaffective Disorder.
What interventions are being tested in trial NCT00817336?
The interventions under investigation include: Placebo (DRUG), D Serine (DRUG).
Who is sponsoring clinical trial NCT00817336?
This trial is sponsored by Nathan Kline Institute for Psychiatric Research, which has 20 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00817336 being conducted?
This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Schizophrenia
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00817336's enrollment target sits among peer trials
16 297th of 315 higher than 16 of 315 other Schizophrenia trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Schizophrenia trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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