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NCT05105542 · ClinicalTrials.gov registry record · Phase 1
M1 Schizophrenia PET Study
A Phase 1 study of Healthy and Schizophrenia, sponsored by Yale University.
- Completed
- Registry status
- Phase 1
- Development phase
- 18
- Enrollment target
- 1
- Study location
NCT05105542: Completed Phase 1 study of Healthy and Schizophrenia, sponsored by Yale University.
NCT05105542 is a Phase 1 study of Healthy and Schizophrenia that has completed, run by Yale University. The registered enrollment target is 18 participants, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05105542, a Phase 1 study of Healthy and Schizophrenia, has completed, sponsored by Yale University.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 18 participants
- Enrollment target
- 1
- Study location
Study Summary
This exploratory study seeks to examine M1 receptor availability in SZ patients and to relate M1 receptor availability to proximal and distal measures of cognitive performance, namely evoked ɣ oscillations in the EEG and verbal memory. Furthermore, the relationship between hippocampal \[11C\]EMO availability (BPND), evoked ɣ oscillations, verbal memory, and measures of illness severity will be explored.
Primary Outcome
Measured by \[11C\]EMO availability (BPND)
Conditions Studied
Interventions
- DEVICE PET Scan
- DRUG 11C-EMO - A Novel PET Radiotracer for Muscarinic M1 Receptor
Study Locations (1)
Connecticut
- Connecticut Mental Health Center - New Haven
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 18 participants |
| Start Date | 2021-04-20 |
| Est. Completion | 2023-10-31 |
| Phase | Phase 1 |
What the finished NCT05105542 record still lists
NCT05105542 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 18 participants, a relatively small participant target, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (97% lower).
The record links to 3 conditions, with Healthy appearing as the primary indexed condition, and to 2 interventions - of which PET Scan is the first listed.
NCT05105542 reports a single indexed study location in Connecticut.
Frequently Asked Questions
What is clinical trial NCT05105542 about?
NCT05105542 is a clinical study titled "M1 Schizophrenia PET Study". This exploratory study seeks to examine M1 receptor availability in SZ patients and to relate M1 receptor availability to proximal and distal measures of cognitive performance, namely evoked ɣ oscillations in the EEG and verbal memory. Furthermore, the relationship between hippocampal \[11C\]EMO ava...
What is the current status of trial NCT05105542?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 18 participants. The study started on 2021-04-20. Estimated completion is 2023-10-31.
What conditions does trial NCT05105542 study?
This clinical trial studies the following conditions: Healthy, Schizophrenia, Schizoaffective Disorder.
What interventions are being tested in trial NCT05105542?
The interventions under investigation include: PET Scan (DEVICE), 11C-EMO - A Novel PET Radiotracer for Muscarinic M1 Receptor (DRUG).
Who is sponsoring clinical trial NCT05105542?
This trial is sponsored by Yale University, which has 1,492 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05105542 being conducted?
This trial has 1 study location across Connecticut. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Healthy
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05105542's enrollment target sits among peer trials
18 904th of 1090 higher than 163 of 1,090 other Healthy trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Healthy trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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