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Renal Cell Carcinoma clinical trials
50 of 122 indexed Renal Cell Carcinoma trials are currently recruiting.
122 US clinical trials · 50 currently recruiting
Renal Cell Carcinoma is the subject of 122 registered US clinical trials on ClinicalTrials.gov, 50 of them currently open to new participants. 10 are in Phase 3-4 (later-stage) and 90 in Phase 1-2 (earlier-stage). The most active sponsor is M.D. Anderson Cancer Center, running 7 of these trials.
The research picture
Renal Cell Carcinoma has 122 registered US clinical trials, 50 of them open to new participants right now, about 41% of the total.
- 50
- recruiting participants now
- 41%
- of trials open to enrollment
- 10
- in Phase 3–4 (later-stage)
- 7
- top sponsor: M.D. Anderson Cancer Center
Active & Recent Trials
122 total, page 3 of 3
Study of Cabiralizumab in Combination With Nivolumab in Patients With Selected Advanced Cancers
Five Prime Therapeutics
NCT02526017
Nivolumab (BMS-936558; MDX-1106) in Combination With Sunitinib, Pazopanib, or Ipilimumab in Subjects With Metastatic Renal Cell Carcinoma (RCC) (CheckMate 016)
Bristol-Myers Squibb
NCT01472081
BNC105P in Combination With Everolimus/Following Everolimus For Progressive Metastatic Clear Cell Renal Cell Carcinoma
Hoosier Cancer Research Network
NCT01034631
A Study of XmAb®20717 in Subjects With Selected Advanced Solid Tumors
Xencor
NCT03517488
Renal Mass Registry
Mayo Clinic
NCT01887574
Phase I Biomarker Study (BMS-936558)
Bristol-Myers Squibb
NCT01358721
Study of IMO-2055 in Metastatic or Locally Recurrent Clear Cell Renal Carcinoma
Idera Pharmaceuticals
NCT00729053
Reproducibility of 18F Uptake by Solid Tumors Using PET Imaging Following Intravenous Administration of (18F) Injection
GE Healthcare
NCT00918281
Two and Three Dimensional Contrast-enhanced Ultrasound for Screening of Renal Cell Carcinoma Recurrence Following Cryoablation
Thomas Jefferson University
NCT02440334
TPST-1120 as Monotherapy and in Combination With Nivolumab in Subjects With Advanced Cancers
Tempest Therapeutics
NCT03829436
A Trial of Niraparib in BAP1 and Other DNA Damage Response (DDR) Deficient Neoplasms (UF-STO-ETI-001)
University of Florida
NCT03207347
Neoadjuvant MEDI 4736 +/- Tremelimumab in Locally Advanced Renal Cell Carcinoma
Moshe Ornstein
NCT02762006
A First in Man Study to Determine the Safety at Various Dose Levels of AGS-16M8F in Advanced Kidney Cancer
Astellas Pharma
NCT01114230
Erlotinib and Sirolimus for the Treatment of Metastatic Renal Cell Carcinoma
University of Colorado, Denver
NCT00353301
Study Testing the Biologic Activity and Safety of a Immunotherapeutic in Patients With Newly Diagnosed Advanced Stage Kidney Cancer in Combination With a Marketed Renal Cell Carcinoma Treatment
Argos Therapeutics
NCT00678119
Serial Ultrasound in Metastatic Renal Cell Carcinoma (mRCC)
Stanford University
NCT04508725
Study Testing the Biologic Activity and Safety of an Immunotherapeutic in Patients With Newly Diagnosed Stage IV Kidney Cancer
Argos Therapeutics
NCT00272649
Sorafenib and RAD001 Renal Cell Carcinoma
University of California, San Francisco
NCT00384969
Circulating Tumors Cells and Circulating Endothelial Cells in Renal Cell Carcinoma
University of Kansas
NCT01173445
Study of CP-461 in Patients With Advanced Renal Cell Cancer
Astellas Pharma
NCT00036036
IRX-2 Regimen Combined With Nivolumab in Recurrent/Metastatic Solid Tumors
H. Lee Moffitt Cancer Center and Research Institute
NCT03758781
A Phase Ib Study of Rad001 and Sutent to Treat Renal Cell Carcinoma
Daniel George, MD
NCT00788060
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 51 |
| Phase 2 | 39 |
| Phase 3 | 10 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Renal Cell Carcinoma Trial Landscape
122 indexed Renal Cell Carcinoma studies · 50 recruiting (41%).
Phase mix: 10 late (III/IV) vs 90 early (I/II).
Top sponsor: M.D. Anderson Cancer Center (7 trials), 9 others listed. 22 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Renal Cell Carcinoma?
PlainTrial tracks 122 US clinical trials for Renal Cell Carcinoma, of which 50 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Renal Cell Carcinoma?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.