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ClinicalTrials.gov 50 recruiting now official registry

Renal Cell Carcinoma clinical trials

50 of 122 indexed Renal Cell Carcinoma trials are currently recruiting.

122 US clinical trials · 50 currently recruiting

Renal Cell Carcinoma is the subject of 122 registered US clinical trials on ClinicalTrials.gov, 50 of them currently open to new participants. 10 are in Phase 3-4 (later-stage) and 90 in Phase 1-2 (earlier-stage). The most active sponsor is M.D. Anderson Cancer Center, running 7 of these trials.

The research picture

Renal Cell Carcinoma has 122 registered US clinical trials, 50 of them open to new participants right now, about 41% of the total.

50
recruiting participants now
41%
of trials open to enrollment
10
in Phase 3–4 (later-stage)
7
top sponsor: M.D. Anderson Cancer Center
Phase 151Phase 239Phase 310

Active & Recent Trials

122 total, page 3 of 3

COMPLETED Phase 1 313 participants

Study of Cabiralizumab in Combination With Nivolumab in Patients With Selected Advanced Cancers

Five Prime Therapeutics

NCT02526017

COMPLETED Phase 1 194 participants

Nivolumab (BMS-936558; MDX-1106) in Combination With Sunitinib, Pazopanib, or Ipilimumab in Subjects With Metastatic Renal Cell Carcinoma (RCC) (CheckMate 016)

Bristol-Myers Squibb

NCT01472081

COMPLETED Phase 1 154 participants

BNC105P in Combination With Everolimus/Following Everolimus For Progressive Metastatic Clear Cell Renal Cell Carcinoma

Hoosier Cancer Research Network

NCT01034631

COMPLETED Phase 1 150 participants

A Study of XmAb®20717 in Subjects With Selected Advanced Solid Tumors

Xencor

NCT03517488

COMPLETED NA 141 participants

Renal Mass Registry

Mayo Clinic

NCT01887574

COMPLETED Phase 1 119 participants

Phase I Biomarker Study (BMS-936558)

Bristol-Myers Squibb

NCT01358721

COMPLETED Phase 2 92 participants

Study of IMO-2055 in Metastatic or Locally Recurrent Clear Cell Renal Carcinoma

Idera Pharmaceuticals

NCT00729053

COMPLETED Phase 2 70 participants

Reproducibility of 18F Uptake by Solid Tumors Using PET Imaging Following Intravenous Administration of (18F) Injection

GE Healthcare

NCT00918281

COMPLETED Phase 2 53 participants

Two and Three Dimensional Contrast-enhanced Ultrasound for Screening of Renal Cell Carcinoma Recurrence Following Cryoablation

Thomas Jefferson University

NCT02440334

COMPLETED Phase 1 38 participants

TPST-1120 as Monotherapy and in Combination With Nivolumab in Subjects With Advanced Cancers

Tempest Therapeutics

NCT03829436

COMPLETED Phase 2 37 participants

A Trial of Niraparib in BAP1 and Other DNA Damage Response (DDR) Deficient Neoplasms (UF-STO-ETI-001)

University of Florida

NCT03207347

COMPLETED Phase 1 29 participants

Neoadjuvant MEDI 4736 +/- Tremelimumab in Locally Advanced Renal Cell Carcinoma

Moshe Ornstein

NCT02762006

COMPLETED Phase 1 26 participants

A First in Man Study to Determine the Safety at Various Dose Levels of AGS-16M8F in Advanced Kidney Cancer

Astellas Pharma

NCT01114230

COMPLETED Phase 2 25 participants

Erlotinib and Sirolimus for the Treatment of Metastatic Renal Cell Carcinoma

University of Colorado, Denver

NCT00353301

COMPLETED Phase 2 25 participants

Study Testing the Biologic Activity and Safety of a Immunotherapeutic in Patients With Newly Diagnosed Advanced Stage Kidney Cancer in Combination With a Marketed Renal Cell Carcinoma Treatment

Argos Therapeutics

NCT00678119

COMPLETED NA 22 participants

Serial Ultrasound in Metastatic Renal Cell Carcinoma (mRCC)

Stanford University

NCT04508725

COMPLETED Phase 1 22 participants

Study Testing the Biologic Activity and Safety of an Immunotherapeutic in Patients With Newly Diagnosed Stage IV Kidney Cancer

Argos Therapeutics

NCT00272649

COMPLETED Phase 1 21 participants

Sorafenib and RAD001 Renal Cell Carcinoma

University of California, San Francisco

NCT00384969

COMPLETED 19 participants

Circulating Tumors Cells and Circulating Endothelial Cells in Renal Cell Carcinoma

University of Kansas

NCT01173445

COMPLETED Phase 2 14 participants

Study of CP-461 in Patients With Advanced Renal Cell Cancer

Astellas Pharma

NCT00036036

COMPLETED Phase 1 12 participants

IRX-2 Regimen Combined With Nivolumab in Recurrent/Metastatic Solid Tumors

H. Lee Moffitt Cancer Center and Research Institute

NCT03758781

COMPLETED Phase 1 5 participants

A Phase Ib Study of Rad001 and Sutent to Treat Renal Cell Carcinoma

Daniel George, MD

NCT00788060

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Phase Distribution

PhaseTrial count
Phase 1 51
Phase 2 39
Phase 3 10

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Renal Cell Carcinoma Trial Landscape

122 indexed Renal Cell Carcinoma studies · 50 recruiting (41%).

Phase mix: 10 late (III/IV) vs 90 early (I/II).

Top sponsor: M.D. Anderson Cancer Center (7 trials), 9 others listed. 22 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Renal Cell Carcinoma?

PlainTrial tracks 122 US clinical trials for Renal Cell Carcinoma, of which 50 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Renal Cell Carcinoma?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.