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NCT00729053 · ClinicalTrials.gov registry record · Phase 2

Study of IMO-2055 in Metastatic or Locally Recurrent Clear Cell Renal Carcinoma

A Phase 2 study of Renal Cell Carcinoma, sponsored by Idera Pharmaceuticals.

Completed
Registry status
Phase 2
Development phase
92
Enrollment target
1
Study location

NCT00729053: Completed Phase 2 study of Renal Cell Carcinoma, sponsored by Idera Pharmaceuticals.

NCT00729053 is a Phase 2 study of Renal Cell Carcinoma that has completed, run by Idera Pharmaceuticals. The registered enrollment target is 92 participants, below the 242-participant average among 121 other Renal Cell Carcinoma trials with a reported enrollment target (62% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00729053, a Phase 2 study of Renal Cell Carcinoma, has completed, sponsored by Idera Pharmaceuticals.

COMPLETED
Registry status
Phase 2
Development phase
92 participants
Enrollment target
1
Study location

Study Summary

* Multi-Center * Randomized * Open-Label Study of single agent IMO-2055 * Patients who have Metastatic or Locally Recurrent Clear Cell Renal Carcinoma (RCC)

Primary Outcome

Best overall objective (i.e., radiological) response by RECIST v1.0 for target lesions: Complete Response (CR): Disappearance of all target lesions; Partial Response (PR): At least a 30% decrease in the sum of the longest diameter of target lesions; Overall Response (OR) = CR + PR in patients with clear cell metastatic or locally recurrent renal cell carcinoma treated with IMO-2055.

Conditions Studied

Interventions

  • DRUG IMO-2055

Study Locations (1)

District of Columbia

  • Georgetown University, Lombardi Cancer Center - Washington D.C.

Trial Details

FieldValue
Enrollment Target 92 participants
Start Date 2004-06
Est. Completion 2008-11
Phase Phase 2
Idera Pharmaceuticals

10 total trials

What the finished NCT00729053 record still lists

NCT00729053 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 92 participants, a relatively small participant target, below the 242-participant average among 121 other Renal Cell Carcinoma trials with a reported enrollment target (62% lower).

The record links to 1 condition, with Renal Cell Carcinoma appearing as the primary indexed condition, and to 1 intervention - of which IMO-2055 is the first listed.

NCT00729053 reports a single indexed study location in District of Columbia.

Frequently Asked Questions

What is clinical trial NCT00729053 about?

NCT00729053 is a clinical study titled "Study of IMO-2055 in Metastatic or Locally Recurrent Clear Cell Renal Carcinoma". * Multi-Center * Randomized * Open-Label Study of single agent IMO-2055 * Patients who have Metastatic or Locally Recurrent Clear Cell Renal Carcinoma (RCC)

What is the current status of trial NCT00729053?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 92 participants. The study started on 2004-06. Estimated completion is 2008-11.

What conditions does trial NCT00729053 study?

This clinical trial studies the following conditions: Renal Cell Carcinoma.

What interventions are being tested in trial NCT00729053?

The interventions under investigation include: IMO-2055 (DRUG).

Who is sponsoring clinical trial NCT00729053?

This trial is sponsored by Idera Pharmaceuticals, which has 10 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00729053 being conducted?

This trial has 1 study location across District of Columbia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Renal Cell Carcinoma

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT00729053's enrollment target sits among peer trials

92 56th of 121 higher than 66 of 121 other Renal Cell Carcinoma trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Renal Cell Carcinoma trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00729053, the US trial registry maintained by the National Library of Medicine. NCT00729053 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.