Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.

2026 data Public-data reference. official source

Ovarian Neoplasms

Open-data reference.

39 US clinical trials · 16 currently recruiting

Active & Recent Trials

RECRUITING Phase 3 1,080 participants

A Two-Part Phase 3 Study of Sofetabart Mipitecan (LY4170156) in Participants With Platinum-Resistant (Part A) and Platinum-Sensitive (Part B) Ovarian Cancer

Eli Lilly and Company

NCT07213804

RECRUITING Phase 1 1,006 participants

A Study of Sigvotatug Vedotin in Advanced Solid Tumors

Seagen, a wholly owned subsidiary of Pfizer

NCT04389632

RECRUITING 1,000 participants

A Diagnostic Test to Evaluate Cancer Risk Before Surgery in Women with an Ovarian Mass

Cleo Diagnostics

NCT06566716

RECRUITING Phase 1 949 participants

A Study of BMS-986340 as Monotherapy and in Combination With Nivolumab or Docetaxel in Participants With Advanced Solid Tumors

Bristol-Myers Squibb

NCT04895709

RECRUITING Phase 3 900 participants

A Clinical Trial of Sac-TMT in People With Non-HRD Positive Advanced Ovarian Cancer (MK-2870-021)

Merck Sharp & Dohme

NCT07318558

RECRUITING Phase 1 540 participants

Study of LY3537982 in Cancer Patients With a Specific Genetic Mutation (KRAS G12C)

Eli Lilly and Company

NCT04956640

RECRUITING Phase 1 495 participants

A Study of LY4170156 in Participants With Selected Advanced Solid Tumors

Eli Lilly and Company

NCT06400472

RECRUITING 250 participants

Developing a Test of Uterine Lavage for the Detection of Ovarian Cancer

Massachusetts General Hospital

NCT04794322

RECRUITING Phase 1 241 participants

A Study of LY4337713 in Participants With FAP-Positive Solid Tumors

Eli Lilly and Company

NCT07213791

RECRUITING 200 participants

Solid Tumor Analysis for HLA Loss of Heterozygosity (LOH) and Apheresis for CAR T- Cell Manufacturing

A2 Biotherapeutics

NCT04981119

RECRUITING Phase 1 160 participants

A Study of DM002 in Patients With Advanced Solid Tumors

Xadcera Biopharmaceutical (Suzhou) Co.

NCT06751329

RECRUITING Phase 1 150 participants

A Study With NKT3964 for Adults With Advanced/Metastatic Solid Tumors

NiKang Therapeutics

NCT06586957

RECRUITING NA 112 participants

Pilot Randomized Controlled Trial of a Collaborative Agenda-setting Intervention (CASI) for Patients With Ovarian Cancer

Dana-Farber Cancer Institute

NCT06543537

RECRUITING Phase 1 100 participants

Anti-Mesothelin TNaive/SCM hYP218 (TNhYP218) CAR T Cells in Participants With Mesothelin-Expressing Solid Tumors Including Mesothelioma

National Cancer Institute (NCI)

NCT06885697

RECRUITING NA 40 participants

Ultrasound Microvessel Imaging for the Evaluation of Ovarian and Adnexal Lesions

Mayo Clinic

NCT07280312

RECRUITING Phase 2 30 participants

A Long-term Treatment Extension Study of Niraparib in Participants Who Completed a Prior GlaxoSmithKline/TESARO-sponsored Niraparib Study

GlaxoSmithKline

NCT04641247

ACTIVE NOT RECRUITING Phase 3 1,400 participants

A Comparison of Platinum-based Therapy With TSR-042 and Niraparib Versus Standard of Care (SOC) Platinum-based Therapy as First-line Treatment of Stage III or IV Nonmucinous Epithelial Ovarian Cancer

Tesaro

NCT03602859

ACTIVE NOT RECRUITING 992 participants

Ascertainment of Peripheral Blood or Saliva Samples for Genetic Epidemiology Studies of Familial Cancers

Memorial Sloan Kettering Cancer Center

NCT00579163

ACTIVE NOT RECRUITING Phase 3 733 participants

A Study of Niraparib (GSK3985771) Maintenance Treatment in Participants With Advanced Ovarian Cancer Following Response on Front-Line Platinum-Based Chemotherapy

Tesaro

NCT02655016

ACTIVE NOT RECRUITING Phase 3 615 participants

Oregovomab Plus Chemo in Newly Diagnosed Patients With Advanced Epithelial Ovarian Cancer Following Optimal Debulking Surgery

CanariaBio

NCT04498117

ACTIVE NOT RECRUITING Phase 2 120 participants

A Study of Disitamab Vedotin in Previously Treated Solid Tumors That Express HER2

Seagen, a wholly owned subsidiary of Pfizer

NCT06003231

ACTIVE NOT RECRUITING Phase 2 92 participants

A Trial of Vigil for Participants With Ovarian Cancer

Gradalis

NCT02346747

ACTIVE NOT RECRUITING Phase 1 19 participants

A Study of SGN-MesoC2 in Advanced Solid Tumors

Seagen, a wholly owned subsidiary of Pfizer

NCT06466187

ACTIVE NOT RECRUITING Phase 2 19 participants

Study of Intravenous and Intraperitoneal Paclitaxel and Oral Nilotinib for Peritoneal Carcinomatosis From Colorectal, Appendiceal, Small Bowel, Gastric, Cholangiocarcinoma, Breast, Ovarian, or Other Gynecologic Primary Cancer

National Cancer Institute (NCI)

NCT05185947

ACTIVE NOT RECRUITING Phase 1 19 participants

AB-1015, an Integrated Circuit T (ICT) Cell Therapy in Patients With Platinum Resistant Epithelial Ovarian Cancer

Arsenal Biosciences

NCT05617755

COMPLETED 613 participants

Biobehavioral-Cytokine Interactions in Ovarian Cancer

Susan Lutgendorf

NCT01113112

COMPLETED Phase 3 581 participants

A Study Comparing the Combination of Trabectedin (YONDELIS) and DOXIL/CAELYX With DOXIL/CAELYX for the Treatment of Advanced-Relapsed Epithelial Ovarian, Primary Peritoneal, or Fallopian Tube Cancer

Janssen Research & Development

NCT01846611

COMPLETED Phase 2 463 participants

A Study of Niraparib in Patients With Ovarian Cancer Who Have Received Three or Four Previous Chemotherapy Regimens

Tesaro

NCT02354586

COMPLETED Phase 2 246 participants

Comparison of Nexavar/Placebo as Maintenance Therapy for Patients With Advanced Ovarian or Primary Peritoneal Cancer

Bayer

NCT00791778

COMPLETED Phase 3 162 participants

A Randomized Trial for Patients With Platinum Resistant Ovarian, Fallopian or Primary Peritoneal Cancer.

Eli Lilly and Company

NCT00191607

COMPLETED Phase 2 150 participants

Testing Drug Sensitivity of Ovarian, Fallopian and Primary Peritoneal Adenocarcinomas

Pierian Biosciences

NCT00443196

COMPLETED NA 130 participants

Guided Imagery in the Perioperative Period in Gynecologic Oncology Patients

University of Michigan

NCT02444195

COMPLETED 100 participants

Microvascular Ultrasonographic Imaging for the Detection of Early Stage Epithelial Ovarian Carcinoma

NYU Langone Health

NCT00531570

COMPLETED Phase 2 97 participants

A Controlled Study of the Effectiveness of Oregovomab (Antibody) Plus Chemotherapy in Advanced Ovarian Cancer

Quest PharmaTech

NCT01616303

COMPLETED Phase 2 61 participants

Study of AMG 479 as Second Line Therapy in Patients With Recurrent Platinum-sensitive Ovarian Cancer

Translational Research in Oncology

NCT00719212

COMPLETED Phase 2 54 participants

EPO906 Therapy in Patients With Advanced Ovarian, Primary Fallopian, or Primary Peritoneal Cancer

Novartis Pharmaceuticals

NCT00035100

COMPLETED Phase 1 25 participants

Study of Motexafin Gadolinium and Docetaxel for Advanced Cancer

Pharmacyclics

NCT00120939

COMPLETED Phase 2 20 participants

Pilot Study of Taxol, Carboplatin, and Bevacizumab in Advanced Stage Ovarian Carcinoma Patients

Gynecologic Oncology Associates

NCT00127920

COMPLETED Phase 2 16 participants

AVE0005 (VEGF Trap) in Patients With Recurrent Symptomatic Malignant Ascites

Sanofi

NCT00396591

Phase Distribution

PhaseTrial count
Early Phase 1 11
Phase 2 12
Phase 3 7

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Ovarian Neoplasms Trial Landscape

ClinicalTrials.gov lists 39 US studies indexed under Ovarian Neoplasms, and 16 of those are currently open to recruitment — roughly 41% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Ovarian Neoplasms shows 7 late-stage studies (Phase 3 and Phase 4 combined) alongside 23 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Ovarian Neoplasms is led by Eli Lilly and Company with 5 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 39 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Ovarian Neoplasms?

PlainTrial tracks 39 US clinical trials for Ovarian Neoplasms, of which 16 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Ovarian Neoplasms?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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