Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Preterm Birth: early-phase trial registry
15 of 40 indexed Preterm Birth trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #368 of 28,707 conditions by registered trial count.
40 US clinical trials · 15 currently recruiting · #368 of 28,707 conditions by registered trial count
Preterm Birth: 40 US clinical trials tracked, 15 recruiting.
Preterm Birth is the subject of 40 registered US clinical trials on ClinicalTrials.gov, 15 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 4 in Phase 1-2 (earlier-stage). The most active sponsor is Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), running 3 of these trials.
Enrollment posture brief
Registry condition preterm-birth
OPEN 15 | RECR 38% | LATE 2 | EARLY 4 | RANK #368 | SPON 3
Volume-matched condition peers
Nearest open-share peer: Acute-graft-versus-host Disease (38% recruiting · 8 trials)
Preterm Birth lists 15 open slots (38% of 40 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Preterm Birth on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Preterm Birth is recruiting below its size-band peers.
15 of 40 indexed trials (37.5%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Preterm Birth trials is spread across many organizations.
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) accounts for 3 of 40 trials (7.5%). 35 distinct sponsors appear on at least one study for this condition label.
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Typical Preterm Birth enrolment sits around 221 participants.
Median target enrolment is 221 among the 40 trials that report a genuine target (sentinel values excluded). 14 of those (35%) plan for fewer than 100 participants.
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Preterm Birth research is mostly interventional.
28 interventional and 12 observational studies make up this index (70% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
40 total, page 1 of 1
Optimal Timing of Routine Cervical Length Measurements During Anatomy Survey
Henry Ford Health System
NCT06822647
Better Birth Outcomes Through Technology, Education, and Reporting
Ohio State University
NCT06261398
Effect of Support for Low-Income Mothers of Preterm Infants
University of Massachusetts, Worcester
NCT06362798
Daily Aspirin vs Split Dosing in High-risk Pregnancies (DASH)
Thomas Jefferson University
NCT06826859
Prospective Evaluation of Pathways for Preterm Birth
John O'Brien, MD
NCT05246579
Reducing Pregnancy Risks: The Mastery Lifestyle Intervention
Microgen
NCT05012072
Stress Phenotypes and Preterm Birth
Columbia University
NCT05229666
Blood Warming in Preterm Infants to Decrease Hypothermia
University of South Carolina
NCT05170633
Mitochondrial DNA Signatures of Poor Aerobic Exercise Trainability in Young Adults Born Preterm
Texas Tech University
NCT06334107
Improvement of PPROM Management With Prophylactic Antimicrobial Therapy (iPROMPT)
Ohio State University
NCT06396078
The Effect of Sulfasalazine on CRH Levels in Pregnant Women
Rutgers, The State University of New Jersey
NCT05703425
Bilateral Infant Stimulation Study
Oregon Health and Science University
NCT06353243
Sodium Awareness in Lactation Trial
The Hospital for Sick Children
NCT06563726
Latency Antibiotics in Previable PPROM, 18 0/7- 22 6/7 WGA
Woman's
NCT04047849
Transition From Donor Milk: a Feasibility Study
Augusta University
NCT06514014
MIRACLE of LIFE Study
Mirvie
NCT06074601
Prematurity Risk Assessment Combined With Clinical Interventions for Improving Neonatal outcoMEs
Sera Prognostics
NCT04301518
Nurse-Family Partnership Impact Evaluation in South Carolina
Harvard School of Public Health (HSPH)
NCT03360539
Positive End-Expiratory Pressure (PEEP) Levels During Resuscitation of Preterm Infants at Birth (The POLAR Trial).
Murdoch Childrens Research Institute
NCT04372953
Promoting Kangaroo Care for Preterm or Low Birthweight Infants in Rural India
University of Massachusetts, Worcester
NCT07231432
Targeting Human Milk Fortification to Improve Preterm Infant Growth and Brain Development
Brigham and Women's Hospital
NCT03977259
Glycemic Control After Antenatal Corticosteroids in Women With Pregestational and Gestational Diabetes
University of Alabama at Birmingham
NCT04542148
Comparative Effectiveness of Treatment Options for Genital Herpes Infection to Reduce Adverse Pregnancy Outcomes
Kaiser Permanente
NCT02986802
Establishment of a Perinatal Database and a Bank of Biological Materials
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NCT00339235
Assessing the Effectiveness and Efficacy of the MyHealthyPregnancy Application
Naima Health
NCT05502510
A Multicenter Assessment of a Spontaneous Preterm Birth Risk Predictor
Sera Prognostics
NCT02787213
Clinical, Biochemical, Histological and Biophysical Parameters in the Prediction of Cerebral Palsy in Patients With Preterm Labor and Premature Rupture of Membranes
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NCT00342667
The Australian Placental Transfusion Study (APTS): Should Very Pre Term Babies Receive a Placental Blood Transfusion at Birth Via Deferring Cord Clamping Versus Standard Cord Clamping Procedures?
University of Sydney
NCT02606058
Cervical Volume by Three-Dimensional Ultrasound as a Predictor of Preterm Delivery
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NCT00342550
Reducing Preterm Births in Underserved Pregnant Women
PHCC
NCT01344616
Tennessee Connections for Better Birth Outcomes
Vanderbilt University
NCT00502697
Mobile Strategy to Reduce the Risk of Recurrent Preterm Birth
Stanford University
NCT04663607
Cord Clamping Level Above or Below Mother's Perineum
The University of Texas Health Science Center, Houston
NCT02659605
The Impact of Vaginal and IM Progestins on the Cervix
University of Pittsburgh
NCT01954095
Enhanced Nutrition for Preterm Infants
University of Minnesota
NCT03238768
Biomarkers of Intra-amniotic Infection in Women With Preterm Premature Ruptured Amniotic Membranes
ProteoGenix
NCT00701350
Supporting Mothers of Preterm Infants
Tufts Medical Center
NCT03013660
Impact of Currently Recommended Postnatal Nutrition on Neonatal Body Composition
Vishal Pandey, M.D.
NCT02622373
Pilot Study to Evaluate a Prototype Electronic Uterine Inhibitor to Prevent Preterm Contractions
St. Luke's-Roosevelt Hospital Center
NCT00212446
Protein and Ultrasound Indicators of Preterm Birth
University of Colorado, Denver
NCT01412931
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 1 |
| Phase 2 | 3 |
| Phase 4 | 2 |
Top Sponsors
Named interventions
Most-linked intervention names on Preterm Birth records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Preterm Birth trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Preterm Birth page
40 registered trials, 15 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 15 Preterm Birth trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) sponsors the most Preterm Birth trials on record, review their full trial history before evaluating a specific study. See Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)'s trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Preterm Birth condition card totals 40 registered trials; most-linked intervention Use of PretermConnect App; top US site state Texas. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.